| Entry |
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| Name |
ADP-dependent short-chain-acyl-CoA hydrolase;
short-chain acyl coenzyme A hydrolase;
propionyl coenzyme A hydrolase;
propionyl-CoA hydrolase;
propionyl-CoA thioesterase;
short-chain acyl-CoA hydrolase;
short-chain acyl-CoA thioesterase
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| Class |
Hydrolases;
Acting on ester bonds;
Thioester hydrolases
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| Sysname |
ADP-dependent-short-chain-acyl-CoA hydrolase
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| Reaction(IUBMB) |
acyl-CoA + H2O = CoA + a carboxylate [RN: R00383]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Requires ADP; inhibited by NADH. Maximum activity is shown with propanoyl-CoA.
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| History |
EC 3.1.2.18 created 1992
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| Reference |
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| Authors |
Alexson SE, Nedergaard J. |
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| Title |
A novel type of short- and medium-chain acyl-CoA hydrolases in brown adipose tissue mitochondria. |
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| Journal |
J Biol Chem 263:13564-71 (1988) |
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| Reference |
|
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| Authors |
Alexson SE, Svensson LT, Nedergaard J. |
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| Title |
NADH-sensitive propionyl-CoA hydrolase in brown-adipose-tissue mitochondria of the rat. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.1.2.18 |
| ExPASy - ENZYME nomenclature database: | 3.1.2.18 |
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| LinkDB |
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