Entry
Name
2-lysophosphatidate phosphatase;
1-acyl-sn-glycerol 3-phosphatase;
CPC3 (gene name);
PHM8 (gene name)
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
1-acyl-sn-glycerol 3-phosphate phosphohydrolase
Reaction(IUBMB)
a 1-acyl-sn-glycerol 3-phosphate + H2O = a 1-acyl-sn-glycerol + phosphate [RN:
R11527 ]
Reaction(KEGG)
Substrate
1-acyl-sn-glycerol 3-phosphate [CPD:
C00681 ];
H2O [CPD:
C00001 ]
Product
1-acyl-sn-glycerol;
phosphate [CPD:
C00009 ]
Comment
The enzyme has been studied from the plants Arachis hypogaea (peanut) and Arabidopsis thaliana (thale cress) and from the yeast Saccharomyces cerevisiae. The enzyme from yeast, but not from the plants, requires Mg2+.
History
EC 3.1.3.106 created 2019
Pathway
Orthology
K23736 2-lysophosphatidate phosphatase
K23737 2-lysophosphatidate phosphatase
Genes
CSAT : 104744444 104763975 104787501
» show all
Taxonomy
Reference
Authors
Shekar S, Tumaney AW, Rao TJ, Rajasekharan R
Title
Isolation of lysophosphatidic acid phosphatase from developing peanut cotyledons.
Journal
Reference
Authors
Reddy VS, Singh AK, Rajasekharan R
Title
The Saccharomyces cerevisiae PHM8 gene encodes a soluble magnesium-dependent lysophosphatidic acid phosphatase.
Journal
Sequence
Reference
Authors
Reddy VS, Rao DK, Rajasekharan R
Title
Functional characterization of lysophosphatidic acid phosphatase from Arabidopsis thaliana.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 3.1.3.106
LinkDB
All DBs