KEGG ENZYME: 3.13.1.3

ENZYME: 3.13.1.3

Entry

EC 3.13.1.3                 Enzyme

Name

2'-hydroxybiphenyl-2-sulfinate desulfinase;
gene dszB-encoded hydrolase;
2-(2-hydroxyphenyl) benzenesulfinate:H2O hydrolase;
DszB;
HBPSi desulfinase;
2-(2-hydroxyphenyl) benzenesulfinate sulfohydrolase;
HPBS desulfinase;
2-(2-hydroxyphenyl)benzenesulfinate hydrolase;
2-(2'-hydroxyphenyl)benzenesulfinate desulfinase;
2-(2-hydroxyphenyl)benzenesulfinate desulfinase

Class

Hydrolases;
Acting on carbon-sulfur bonds;
Acting on carbon-sulfur bonds

Sysname

2'-hydroxybiphenyl-2-sulfinate sulfohydrolase

Reaction(IUBMB)

2'-hydroxybiphenyl-2-sulfinate + H2O = 2-hydroxybiphenyl + sulfite [RN:R07311]

Reaction(KEGG)

R07311

Substrate

2'-hydroxybiphenyl-2-sulfinate [CPD:C06742];
H2O [CPD:C00001]

Product

2-hydroxybiphenyl [CPD:C02499];
sulfite [CPD:C00094]

Comment

The enzyme from Rhodococcus sp. strain IGTS8 is encoded by the plasmid-encoded dibenzothiophene-desulfurization (dsz) operon. The enzyme has a narrow substrate specificity with biphenyl-2-sulfinate being the only other substrate known to date [2].

History

EC 3.13.1.3 created 2000 as EC 3.1.2.24, transferred 2005 to EC 3.13.1.3

Orthology

K05977

2'-hydroxybiphenyl-2-sulfinate desulfinase

Genes

MAV:

MAV_3808

MYO:	OEM_10430 OEM_p100030

MBRD:

MBRA_09610

MKY:	IWGMT90018_59570

MWU:	PT015_13395

MBOK:

MBOE_20030

MFG:	K6L26_01625 K6L26_21995

MGO:	AFA91_16300

MABL:

MMASJCM_2558

MHER:

K3U94_11715

GTA:	BCM27_00645

GOS:	QAD21_00560

GOJ:	GR168_00650

GHN:	MVF96_00625

» show all

Reference

1 [PMID:9308179]

Authors

Oldfield C, Pogrebinsky O, Simmonds J, Olson ES, Kulpa CF.

Title

Elucidation of the metabolic pathway for dibenzothiophene desulphurization by Rhodococcus sp. strain IGTS8 (ATCC 53968).

Journal

Microbiology 143 ( Pt 9):2961-73 (1997)
DOI:10.1099/00221287-143-9-2961

Reference

2 [PMID:12147352]

Authors

Nakayama N, Matsubara T, Ohshiro T, Moroto Y, Kawata Y, Koizumi K, Hirakawa Y, Suzuki M, Maruhashi K, Izumi Y, Kurane R.

Title

A novel enzyme, 2'-hydroxybiphenyl-2-sulfinate desulfinase (DszB), from a dibenzothiophene-desulfurizing bacterium Rhodococcus erythropolis KA2-5-1: gene overexpression and enzyme characterization.

Journal

Biochim Biophys Acta 1598:122-30 (2002)
DOI:10.1016/S0167-4838(02)00365-5

Reference

3 [PMID:12801508]

Authors

Watkins LM, Rodriguez R, Schneider D, Broderick R, Cruz M, Chambers R, Ruckman E, Cody M, Mrachko GT.

Title

Purification and characterization of the aromatic desulfinase, 2-(2'-hydroxyphenyl)benzenesulfinate desulfinase.

Journal

Arch Biochem Biophys 415:14-23 (2003)
DOI:10.1016/S0003-9861(03)00230-3

Other DBs

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