KEGG   ENZYME: 3.2.2.26
Entry
EC 3.2.2.26                 Enzyme                                 
Name
futalosine hydrolase;
futalosine nucleosidase;
MqnB (ambiguous)
Class
Hydrolases;
Glycosylases;
Hydrolysing N-glycosyl compounds
Sysname
futalosine ribohydrolase
Reaction(IUBMB)
futalosine + H2O = dehypoxanthine futalosine + hypoxanthine [RN:R08587]
Reaction(KEGG)
R08587
Substrate
futalosine [CPD:C16999];
H2O [CPD:C00001]
Product
dehypoxanthine futalosine [CPD:C17010];
hypoxanthine [CPD:C00262]
Comment
This enzyme, which is specific for futalosine, catalyses the second step of a novel menaquinone biosynthetic pathway that is found in some prokaryotes.
History
EC 3.2.2.26 created 2008
Pathway
ec00130  Ubiquinone and other terpenoid-quinone biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K11783  futalosine hydrolase
Genes
LHKLHK_00108
PSENH8B_0057
AQLBXU06_16280
CHIZHQ393_12950
CFONHZU75_09255
VOGLCH97_11735
UPVEJN92_04145
UPIEJG51_007845
GSUGSU0453(mqnB)
GSKKN400_0426(mqnB)
GMEGmet_3381(mqnB)
GPIGPICK_15470
GAOA2G06_02095
GBZJZM60_06610(mqnB)
GEMGM21_0612
GEBGM18_3755
GEFFO488_01470(mqnB)
GURGura_0685
GEOGeob_0898(mqnB)
GLOGlov_0458
GBMGbem_0598(mqnB)
GBNGEOBRER4_06040(mqnB)
GERKP004_02270(mqnB)
GSUBKP001_13220(mqnB)
GNTKP003_01910(mqnB)
GPLM1B72_18695(mqnB)
PCAPcar_3117(mqnB)
PACEA6070_00960
PEFA7E78_09160
PPDPpro_3274
DESDSOUD_0020(mqnB)
DEUDBW_3613
DVEDESUT3_01260(mqnB)
DEPAOP6_2912(mqnB)
DVUDVU_3178
DVLDvul_0209
DVMDvMF_2491
DVGDeval_2935
DDSDdes_1911
DFIAXF13_00485
DPGDESPIGER_1540
DEFCNY67_02625(mqnB)
DTRRSDT_0457(mqnB)
DFLDFE_2958
DSDGD606_08870(mqnB)
DMADMR_35800
DCBC3Y92_04075(mqnB)
DGGDGI_2626
DDEDde_3188
DMSE8L03_10275(mqnB)
DSADesal_0762
DHYDESAM_20138
DAFDesaf_1765
DASDaes_0800
DPIBN4_11672
DEJAWY79_05195
PPRFDPRO_2568(mqnB)
PSELGM415_07560(mqnB)
DDNDND132_1764
DSXGD604_14550(mqnB)
PBIZLWC08_10920(mqnB)
PSYFN1030_12900(mqnB)
DBADbac_3009
DOAAXF15_03675
DRTDret_2414
DSFUWK_02144
DAKDaAHT2_0723
DPRDespr_2780
DEOCAY53_08025
DOGHP555_06720(mqnB)
DBKDGMP_06000(mqnB)
DOLDole_1278
DMLDmul_05540
DATHRM2_27040
DTOTOL2_C37140
DLIdnl_58580(mqnB)
DEKDSLASN_15570
ACPA2cp1_1429
AFWAnae109_1740
ANKAnaeK_1331
VINAKJ08_0247
LLUAKJ09_04863
SFUSfum_1814
DAXFDQ92_05880
DBRDeba_2375
DHRLGS26_03770(mqnB)
RIIFFM53_001600
BSHILGQ02_02045
BCOBcell_0852
BHABH2690
BCLABC0988
BLEBleG1_0976
BKWBkAM31D_01800(mqnB)
BPFBpOF4_09540
ASEDIRT44_08840
FPNABE65_001850
FARABE41_001800
RUEDT065_15475
SALEEPH95_15390
SCIBHUG20_03820
SCIAHUG15_04970
AIAAWH56_010255
BBEVBBEV_2867
BSEBsel_0478
PSUAFLK61_25365
SLMSMM221_11635
BBEBBR47_09530
BLRBRLA_c006120
BFMBP422_30110
BAGRBA6348_24020
BRWGOP56_18965
BCHSJNE38_04590
BCOPJD108_18565
PJDPjdr2_0345
GYMGYMC10_1380
PPYPPE_03890
PPMPPSC2_20425
PPOPPM_4092(M1_4500)
PPOLX809_36560
PPQPPSQR21_041300
PPOYRE92_16780
PMSKNP414_07865
PMQPM3016_7383
PMWB2K_40540
PTAHPL003_01395
PLVERIC2_c17880
PSABPSAB_23170
PDUPDUR_26390
PBDPBOR_34495
PGMPGRAT_30845
PODPODO_29285
PAENP40081_35815
PAEFR50345_29395
PAEQR50912_32460
PSTEPSTEL_25845
PAEAR70723_31260
PAEER70331_30025
PAEHH70357_33555
PAEJH70737_29040
PBJVN24_21955
PIHUB51_10820
PRIPRIO_6458
PSONJI735_07000
PPEOABE82_20475
PNPIJ22_04090
POWIJ21_28570
PBVAR543_07275
PXLBS614_09385
PYGAWM70_01080
PSWUSY83_01250
PDHB9T62_30180
PIBBBD41_07895
PCXLPB68_20820
PKBB4V02_04885
PAIHASL14_17440
PVOPVOR_08980
PLWD5F53_22705
PLENEIM92_16975
PPSCEHS13_34510
PLUTEI981_16050
PALBEJC50_02700
PCHIPC41400_26725
PBKBack11_20860(mqnB)
PPRTET464_10180
PBACHUB98_22370
PRZGZH47_17370
PLYCGXP70_29120
PSOPKP014_01785
PTRIKDC22_31390
PALOE6C60_1147
PCELHUB94_22220
PTJJRJ22_27735
PALRHGI30_02290
TCOTheco_3963
ANXACH33_15920
ASOCCB4_02170(mqnB)
ATHEK3F53_02965
COHEAV92_18065
COHNKCTCHS21_47820(mqnB)
CCHLFPL14_08290
CHEBHH215_15730
SACAFFV09_15535
TUMCBW65_09890
TABCIG75_17910
LFBC1X05_05630
TVUAB849_006265
SGYSgly_3170
DORDesor_0800
DMIDesmer_0821
DRMDred_3235
DAEDtox_4200
DAUDaud_0261
TJRTherJR_0139
DGIDesgi_0052
SCOSCO4327(SCD12A.10c)
SALBXNR_2324
SMASAVERM_3905(mqnB)
SGRSGR_3174
SGBWQO_19855
SCBSCAB_50841
SSXSACTE_3764
SVLStrvi_8732
SHYSHJG_4799
SHOSHJGH_4562
SRCM271_28000
SMALSMALA_3437
SSOII1A49_20940(mqnB)
SFASfla_2741
SBHSBI_04915
SVESVEN_4139
SDVBN159_4910
SALSSLNWT_0701 SLNWT_4242
STRPF750_4057
SFISFUL_4158
SCIB446_17345
SALUDC74_4819
SALLSAZ_25775
SLVSLIV_16760(mqnB)
SGUSGLAU_15280
SVTSVTN_21500
STREGZL_04008
SCWTU94_18475
SLDT261_3374
SLCSL103_32125
SXISXIM_32090
STRMM444_16080
STRCAA958_13265
SAMBSAM23877_3378(mqnB)
SPRISPRI_4149
SCZABE83_15455
SCXAS200_25570
SRWTUE45_04208(mqnB)
STRFASR50_18675
SLEsle_39460(sle_39460)
SRNA4G23_02416(mqnB)
SPAVSpa2297_14655
STRTA8713_13720
SCLFBB341_12075
SGSAVL59_44750
STSIA4E84_17895
SKYD0C37_13410
SALWCP975_15595
SGMGCM10017557_37400(mqnB)
SCADDN051_21835
SPHWNFX46_37730
SLSSLINC_3823
SNRSNOUR_17860
SPLULK06_018400
STRDNI25_21950
SNWBBN63_19240
SAUOBV401_20650
SSIAA7J05_19820
SVUB1H20_14260
SPUNBFF78_23560
SGVB1H19_24645
SLAUSLA_4259
SALFSMD44_03818
SALJSMD11_2817
SLXSLAV_17350(mqnB)
STROSTRMOE7_23260
SFKKY5_3626
SNZDC008_15315
SGEDWG14_04696(mqnB)
SRJSRO_4101
SLKSLUN_17775
SDXC4B68_22355
SGDELQ87_21535
SQZFQU76_13905
SCYAEJ357_20480
SASTCD934_13150
SNQCP978_15525
STIRDDW44_13610
SKACP970_24160
SGZC0216_28645
SVNCP980_18860
SNKCP967_14690
SHAWCEB94_18325
SRKFGW37_19525
SFICEIZ62_18225
SGALCP966_16255
SSPODDQ41_13610
SVRCP971_14395
SPADDVK44_19475
SFYGFH48_22685
SAQUEJC51_22700
SGFHEP81_04274
SCAVCVT27_19065
SSEOD0Z67_12785
SBYH7H31_20185(mqnB)
SRIMCP984_15960
SSUBCP968_18845
SPHVF9278_21185
SCINCP977_19545
SFUGCNQ36_15455
SPACB1H29_20830
STSUB7R87_13440
SCHACP983_23700
SGXH4W23_22895
SCOECP976_19865
SBATG4Z16_19405
SSPBCP982_19680
SNFJYK04_03964(mqnB)
SPLACP981_23285
SBROGQF42_20790
STUIGCM10017668_30880(mqnB)
SATAC5746_23215
SCHFIPT68_16375
SHUNDWB77_03527(mqnB)
SHARHUT13_16570
SCYGS1361_18070(mqnB)
SFEUIM697_03695
SLIAHA039_19535
SDWK7C20_22145
SVDCP969_17995
SCALI6J39_14495
SAUHSU9_020260
SFBCP974_13260
SMOBJ7W19_19155
SPRACP972_16155
SPEUCGZ69_16005
SROIIAG44_22945
SXNIAG42_15750
SGJIAG43_13715
SHKJ2N69_15985
SANUK7396_14765
SDDD9753_19725
SACTDMT42_17515
SMAOCAG99_15800
SGOBtest1122_10290
SINEKI385_27245
SLFJEQ17_20990
SDECL3078_20345
SAOVG3H79_20475
SDURM4V62_23735
SYANNRK68_15095
SRUGF0345_16650
SCTSCAT_2423
SCYSCATT_24070
KSKKSE_44340
KABB7C62_20040
KAUB6264_09440
KITCFP65_4403
STRIC7M71_012745 C7M71_025715
YIALO772_15240
STRHGXP74_03910
ABRYNYE86_03785
FRAFrancci3_4421
FREFranean1_0152
FRIFraEuI1c_0099
FALFRAAL6734
FSYFsymDg_0158
ACEAcel_0106
STPStrop_0412
SAQSare_0500
MAUMicau_0503
MILML5_0694
MICBMicB006_0517
MTUACSH63_22710
MICHFJK98_02780
MTEMGCE86_28125
MCABHXZ27_02670
MSAGGCM10017556_30740
VMAVAB18032_06575
MCRAID554_10585
ASEACPL_536
AMSAMIS_3780
ACTNL083_0510
AFSAFR_02110
ACTSACWT_0421
AIHAiant_46230
ACTRAsp14428_42490
PLKCIK06_02690
PLABC6361_19520
PLATC6W10_29125
PFLAPflav_075420
PSUUPsuf_037850
VERHUT12_03010
ATLAthai_03370(mqnB)
ASERAsera_03960(mqnB)
PRYPrubr_20360
CATICS0771_17020(mqnB)
DVCDvina_31125 Dvina_50640
DFUDfulv_28925
DROSDrose_22090
DAURDaura_29740 Daura_49170
CCAZCOUCH_37460
CAICaci_8090
SNASnas_5857
NAVJQS30_00550(mqnB)
GLYK3N28_16420(mqnB)
JTLM6D93_03735
ERZER308_16375
DRADR_1664
DGEDgeo_0447
DDRDeide_07551
DMRDeima_0691
DPTDeipr_0614
DGODGo_CA1229
DPDDeipe_0942
DSWQR90_12330
DCHSY84_12885
DABAUC44_11995
DPUSU48_04135
DEZDKM44_00105(mqnB)
DWUDVJ83_05855(mqnB)
DFCDFI_06205
DEINDAAJ005_06390(mqnB)
DGADEGR_07670(mqnB)
DPHEHF33_08980(mqnB)
DRDLMT64_02460(mqnB)
DRBN0D28_00805(mqnB)
TRATrad_1280
TTHTT_C0188
TTJTTHA0556(TTHA0556)
TTSThthe16_0556
TTLTtJL18_1519
TSCTSC_c08340
THCTCCBUS3UF1_9240
TOSTheos_0782
TAQTO73_1348
TPARAV541_07910
TBCA0O31_01992(mqnB)
TANTKNN15_09120(mqnB)
MRBMrub_0986
MREK649_04570
MSVMesil_1255
MTAIMtai_v1c19560
OPROcepr_2008
MHDMarky_0101
RBARB1081
PIRVN12_00835(mqnB)
RULUC8_17830(mqnB)
MFFMFFC18_08390(mqnB)
ROLCA51_17570(mqnB)
AHELQ31a_62190(pfs)
LCREPla8534_45380(mqnB)
RLCK227x_44820(mqnB)
FMRFuma_02702
BROCIPI25_08950(mqnB)
BPITBPIT_22640
JETL3J17_15785(mqnB)
CTMCabther_A0064
CVLJ8C06_00310(mqnB)
CHLOJ8C02_00300(mqnB)
ABACLuPra_05981
THYDTTHT_2100(mtn)
SCORJ3U87_18095(mqnB)
FSUFisuc_1888
FSCFSU_2393
GAUGAU_3531
GPHGEMMAAP_16935
GGRHKW67_17260
ALDGFH31_00390
AOKA3BBH6_14840
ACOUA5CBH24_11490
AITAI2BBH_19930
RBCBN938_0240
TTZFHG85_03570
BLQL21SP5_03128
BACCBRDCF_p520
DORIFH5T_01435
DRCG0Q07_07290(mqnB)
MCOSGM418_04875(mqnB)
MBASALGA_1067
CPICpin_6958
CBAECOR50_09000(mqnB)
CHITFW415_23880(mqnB)
CHIHGWR21_14115(mqnB)
COYHF329_30005(mqnB)
CFILMYF79_30500(mqnB)
NKONiako_5078
NSONIASO_19250
NIAA8C56_01805
FLASY85_08220
FGGFSB75_07940(mqnB)
ARBA9P82_12565
ARKD6B99_16710(mqnB)
AGIFSB73_08605(mqnB)
ARACE0W69_017700(mqnB)
ATEEK9M52_09010(mqnB)
PSEGD3H65_29210(mqnB)
PGINFRZ67_04480(mqnB)
PGOFSB84_01780(mqnB)
FLSGLV81_15180(mqnB)
LACSH4075_04065(mqnB)
FEIK9M53_09025(mqnB)
FLPLK994_09895
FLCKJS93_01580(mqnB)
FLVKJS94_00915(mqnB)
HHYHalhy_0301
SGNSGRA_1216(mtnN)
PHEPhep_4151
PEPAQ505_01225
PCMAY601_4379
PSTYBFS30_06115
PGSCPT03_17650(mqnB)
PEJFYC62_13115(mqnB)
PEKFFJ24_022600(mqnB)
PROEH9L23_22875(mqnB)
PEXIZT61_12785(mqnB)
PSNPedsa_2886
SHGSph21_1320
SHTKO02_00760
SPHNBV902_01150
SMIZ4412673_04064
SPSCE2P86_17945(mqnB)
SPHZE3D81_00195(mqnB)
SPHEGFH32_18015(mqnB)
SPDRG6053_30415(mqnB)
SDJNCTC13534_05579
STHANCTC11429_01601
SSPII6J01_08020(mqnB)
SMUII6J00_16790(mqnB)
SSIYJVX97_03220(mqnB)
SCNSolca_4157
MUPA0256_04250
MUCMuYL_0222
MUHHYN43_026490(mqnB)
MGINFRZ54_01410(mqnB)
MGKFSB76_13665(mqnB)
MRUBDEO27_028790(mqnB)
MGOSDIU38_024785(mqnB)
MMABHQ865_23210(mqnB)
MGIKGO620_015405(mqnB)
MDJLLH06_00745(mqnB)
AGDFRZ59_03595(mqnB)
OLIFKG96_03550(mqnB)
SBXCA265_21880
HRSHER32_15325
TTKTST_1334(mtnN)
DINSelin_1732
DDFDEFDS_1229
DAPDacet_1934
GTLEP073_09485
CNICalni_1363
FSIFlexsi_1429
MSCHN508_002024(mqnB)
TYETHEYE_A0852
DTPJZK55_03000
TIDThein_1289
TOPTOPB45_0116
TCMHL41_06220
THETF1847_00690
CTHITHC_1277
TAVG4V39_08435(mqnB)
TMAIFVE67_06625(mqnB)
NLIG3M70_06995
 » show all
Reference
1  [PMID:18801996]
  Authors
Hiratsuka T, Furihata K, Ishikawa J, Yamashita H, Itoh N, Seto H, Dairi T
  Title
An alternative menaquinone biosynthetic pathway operating in microorganisms.
  Journal
Science 321:1670-3 (2008)
DOI:10.1126/science.1160446
  Sequence
[sco:SCO4327] [ttj:TTHA0556]
Other DBs
ExplorEnz - The Enzyme Database: 3.2.2.26
IUBMB Enzyme Nomenclature: 3.2.2.26
ExPASy - ENZYME nomenclature database: 3.2.2.26
BRENDA, the Enzyme Database: 3.2.2.26
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