KEGG   ENZYME: 3.4.24.35
Entry
EC 3.4.24.35                Enzyme                                 
Name
gelatinase B;
92-kDa gelatinase;
matrix metalloproteinase 9;
type V collagenase;
92-kDa type IV collagenase;
macrophage gelatinase;
95 kDa type IV collagenase/gelatinase;
collagenase IV (ambiguous);
collagenase type IV (ambiguous);
gelatinase MMP 9;
MMP 9;
type IV collagen metalloproteinase (ambiguous)
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
Reaction(IUBMB)
Cleavage of gelatin types I and V and collagen types IV and V
Comment
Similar to gelatinase A, but possesses a further domain . In peptidase family M10 (interstitial collagenase family)
History
EC 3.4.24.35 created 1992
Orthology
K01403  matrix metalloproteinase-9 (gelatinase B)
Genes
HSA4318(MMP9)
PTR458294(MMP9)
PPS100974722(MMP9)
GGO101138361(MMP9)
PON100455867(MMP9)
NLE100587873(MMP9)
MCC708084(MMP9)
MCF102117693(MMP9)
CSAB103245064(MMP9)
CATY105588504(MMP9)
PANU101003884(MMP9)
TGE112632530(MMP9)
RBB108533326(MMP9)
TFN117068860(MMP9)
PTEH111530012(MMP9)
CJC100415095(MMP9)
SBQ101036569(MMP9)
CSYR103260266(MMP9)
MMUR105859286(MMP9)
OGA100942813(MMP9)
MMU17395(Mmp9)
MCAL110290048(Mmp9)
MPAH110318332(Mmp9)
RNO81687(Mmp9)
MCOC116092533(Mmp9)
MUN110549307(Mmp9)
CGE100770707(Mmp9)
PLEU114692635(Mmp9)
NGI103751232(Mmp9)
HGL101717243(Mmp9)
CPOC100728510(Mmp9)
CCAN109689278(Mmp9)
DORD105981538(Mmp9)
DSP122120286(Mmp9)
NCAR124977457
OCU100008993(MMP9)
OPI101532937(MMP9)
TUP102487885(MMP9)
CFA403885(MMP9)
VVP112931929(MMP9)
VLG121478135(MMP9)
AML100475429(MMP9)
UMR103669705(MMP9)
UAH113258671(MMP9)
UAR123797065(MMP9)
ELK111141396
LLV125109962
MPUF101677351(MMP9)
ORO101380511(MMP9)
EJU114223146(MMP9)
ZCA113937554(MMP9)
MLX118011551(MMP9)
FCA101084185(MMP9)
PYU121012098(MMP9)
PBG122467326(MMP9)
PTG102959269(MMP9)
PPAD109272345(MMP9)
AJU106969010(MMP9)
HHV120243271(MMP9)
BTA282871(MMP9)
BOM102273141(MMP9)
BIU109567506(MMP9)
BBUB102414528(MMP9)
CHX102168469(MMP9)
OAS100192422(MMP9)
ODA120869126(MMP9)
CCAD122448603(MMP9)
SSC654325(MMP9)
CFR102509767(MMP9)
CBAI105071885(MMP9)
CDK105087845(MMP9)
VPC102528343(MMP9)
BACU103016628(MMP9)
LVE103086240(MMP9)
OOR101277919(MMP9)
DLE111170142(MMP9)
PCAD102977941(MMP9)
PSIU116740660(MMP9)
ECB100056599(MMP9)
EPZ103551921(MMP9)
EAI106843045(MMP9)
MYB102260281(MMP9)
MYD102765342(MMP9)
MMYO118663534(MMP9)
MLF102417294(MMP9)
MNA107530893(MMP9)
PKL118707740(MMP9)
HAI109379910(MMP9)
DRO112304108(MMP9)
SHON118985553(MMP9)
AJM119063184(MMP9)
PDIC114506744(MMP9)
PHAS123815340(MMP9)
MMF118618723(MMP9)
RFQ117015819(MMP9)
PALE102889517(MMP9)
PGIG120603391(MMP9)
PVP105298192(MMP9)
RAY107514536(MMP9)
MJV108392902(MMP9)
TOD119237691 119254508(MMP9)
SARA101545527(MMP9)
LAV100664260(MMP9)
TMU101347888
DNM101438233(MMP9)
MDO100022144(MMP9)
GAS123235271(MMP9)
SHR100934566(MMP9)
PCW110193756(MMP9)
GGA395387(MMP9)
PCOC116225560(MMP9)
MGP100540313(MMP9)
CJO107323128(MMP9)
NMEL110408379(MMP9)
APLA101793782(MMP9)
ACYG106047143(MMP9)
AFUL116495864(MMP9)
TGU100227728(MMP9)
LSR110476147 110479789
SCAN103818645
PMOA120497831(MMP9)
OTC121343784(MMP9)
PRUF121359703(MMP9)
GFR102042403(MMP9)
FAB101813444(MMP9)
PHI102112681(MMP9)
PMAJ107213224(MMP9)
CCAE111938166(MMP9)
CCW104687728(MMP9)
ETL114063050(MMP9)
ZAB102071782(MMP9)
FPG101912755(MMP9)
FCH102053895(MMP9)
CLV102094215(MMP9)
EGZ104127957(MMP9)
NNI104018301(MMP9)
TALA116965374(MMP9)
ACHC115339854(MMP9)
AAM106497585(MMP9)
AROW112972708(MMP9)
NPD112949634(MMP9)
DNE112995216(MMP9)
ASN102368987(MMP9)
AMJ106736975(MMP9)
CPOO109313124(MMP9)
GGN109292470(MMP9)
CMY102942105(MMP9)
CPIC101933485 101936391(MMP9) 101945434 101945994
TST117886137(MMP9)
CABI116831183(MMP9)
MRV120379789(MMP9)
PVT110086226(MMP9) 110089938
SUND121928069(MMP9) 121933666
PBI103064710(MMP9)
PMUR107298160
TSR106556466(MMP9)
PGUT117668957 117669601(MMP9) 117669616
VKO123018871(MMP9)
PMUA114599897(MMP9)
ZVI118089286(MMP9)
GJA107114899(MMP9)
STOW125432346(MMP9)
XLA100037129(mmp9.2.L) 108702732(mmp9.2.S) 379663(mmp9.S)
XTR100494738(mmp9.2) 448591(mmp9.1)
NPR108789114(MMP9)
RTEM120918563(MMP9) 120945126(ELSPBP1)
BBUF121004276(MMP9)
BGAR122940235(MMP9)
DRE406397(mmp9)
SRX107712005(mmp9) 107731127
SANH107668111 107678941
SGH107550477 107591829
CCAR109094610 109103880
CAUA113077664 113093908 113107624
PPRM120469206(mmp9)
MAMB125279809(mmp9)
IPU100304980(mmp9) 108265954
PHYP113527001
SMEO124399997 124400510
TFD113656210(mmp9) 113656211
AMEX103023931
EEE113567502(mmp9)
TRU653023(mmp9)
TNGGSTEN00028167G001
LCO104926671(mmp9)
NCC104964418(mmp9)
CGOB115011368(mmp9)
ELY117257887(mmp9)
PLEP121947015(mmp9)
SLUC116040707(mmp9)
ECRA117947572(mmp9)
PFLV114558244(mmp9)
GAT120829481(mmp9)
PPUG119199474 119222598(mmp9)
MSAM119905578(mmp9)
CUD121518119(mmp9)
MZE101483885(mmp9)
ONL100701193(mmp9)
OAU116309707(mmp9)
OLA100125420(mmp9)
OML112159032(mmp9)
XMA102229854(mmp9)
XCO114145245(mmp9)
XHE116726464(mmp9)
PRET103467157 103467158 103467281
PFOR103129676 103129678 103132306 103132307 103132308 103132731 103132870 103151091(mmp9)
PLAI106942044 106942810 106942812 106944060 106956283
PMEI106912111 106912139 106912965 106913043 106913372 106928272 106928273 106928275(mmp9) 106928276
GAF122837222(mmp9)
CVG107087470(mmp9)
CTUL119782156(mmp9)
GMU124877667(mmp9)
NFU107390812(mmp9)
KMR108236720(mmp9)
ALIM106525577(mmp9)
NWH119417004(mmp9)
AOCE111583419(mmp9)
CSEM103384600(mmp9)
POV109630977(mmp9)
SSEN122777084(mmp9)
HHIP117764810(mmp9)
LCF108876510(mmp9)
SDU111219019(mmp9)
SLAL111670614(mmp9)
XGL120804338(mmp9)
HCQ109510353 109510355
BPEC110164611(mmp9)
MALB109972052(mmp9)
SASA100195428(mmp9) 106566399
OTW112216391 112222403
OMY100136060(mmp9) 110492670
OGO124032362 124045492
ONE115101934(mmp9) 115132546
SALP112073798 112073904
SNH120059041 120061527
ELS105023758(mmp9)
SFM108931255(mmp9)
PKI111855870(mmp9)
AANG118208714(mmp9)
LOC102692037(mmp9) 107076748
PSPA121298131 121319439
ARUT117394324 117404302 117428207
LCM102358076(MMP9)
CMK103191321(mmp9)
RTP109913301
SCLV120333348
PJA122266828
PTRU123515097
LSM121122943 121126324 121128006 121128090 121128529
ATEN116292923
 » show all
Reference
1  [PMID:3680518]
  Authors
Hibbs MS, Hoidal JR, Kang AH.
  Title
Expression of a metalloproteinase that degrades native type V collagen and denatured collagens by cultured human alveolar macrophages.
  Journal
J Clin Invest 80:1644-50 (1987)
DOI:10.1172/JCI113253
Reference
2  [PMID:2551898]
  Authors
Wilhelm SM, Collier IE, Marmer BL, Eisen AZ, Grant GA, Goldberg GI
  Title
SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages.
  Journal
J Biol Chem 264:17213-21 (1989)
  Sequence
[hsa:4318]
Reference
3  [PMID:2165210]
  Authors
Mainardi CL, Hasty KA.
  Title
Secretion and glycosylation of rabbit macrophage type V collagenase.
  Journal
Matrix 10:84-90 (1990)
DOI:10.1016/s0934-8832(11)80174-5
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.35
IUBMB Enzyme Nomenclature: 3.4.24.35
ExPASy - ENZYME nomenclature database: 3.4.24.35
BRENDA, the Enzyme Database: 3.4.24.35
CAS: 146480-36-6
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