KEGG   ENZYME: 3.5.1.125
Entry
EC 3.5.1.125                Enzyme                                 
Name
N2-acetyl-L-2,4-diaminobutanoate deacetylase;
doeB (gene name)
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
Sysname
(2S)-2-acetamido-4-aminobutanoate amidohydrolase
Reaction(IUBMB)
(2S)-2-acetamido-4-aminobutanoate + H2O = L-2,4-diaminobutanoate + acetate [RN:R09801]
Reaction(KEGG)
R09801
Substrate
(2S)-2-acetamido-4-aminobutanoate [CPD:C19929];
H2O [CPD:C00001]
Product
L-2,4-diaminobutanoate [CPD:C03283];
acetate [CPD:C00033]
Comment
The enzyme, found in bacteria, has no activity with (2S)-4-acetamido-2-aminobutanoate (cf. EC 3.5.4.44, ectoine hydrolase).
History
EC 3.5.1.125 created 2017
Pathway
ec00260  Glycine, serine and threonine metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K15784  N2-acetyl-L-2,4-diaminobutanoate deacetylase
Genes
CAMAF384_12940
IZHFEM41_17290(doeB)
SMAFD781_2282
SRZAXX16_2865
SERMCLM71_11805(doeB)
SRHZFO014_21985(doeB)
VAGN646_3800
VEXVEA_000633
VDBAL552_04810(doeB)
VNAPN96_17660
VEJVEJY3_17221
VNLD3H41_20750(doeB)
VKABTD91_20445(doeB)
GHOAL542_02295(doeB)
SALYE8E00_14715(doeB)
SKSFCN78_14015(doeB)
SCOTHBA18_14655(doeB)
PAPPSPA7_4379(eutE)
PMKMDS_0057
PFUWKF707C_22190
PCQPcP3B5_00240
PMUIG4G71_02700(doeB)
PPUPP_4423
PPTPPS_0720
PPIYSA_00597
PPUHB479_04045
PPUDDW66_0727 DW66_1176
PFVPsefu_0030
PMONX969_02020
PMOTX970_02010
PPJRK21_04288
PFEPSF113_4815
PMANOU5_4502(eutE)
PCGAXG94_20240
PSTTCH92_00110
PBAPSEBR_a4652
PBCCD58_05100
PDRH681_00260
PALLUYA_00165
PUMHGP31_27395(doeB)
PLALFXN65_00115(doeB)
PSEJHNQ25_01230(doeB)
PKHJLK41_00145(doeB)
PTYJWV26_10525(doeB)
PMAOPMYSY11_0799(doeB)
PANHHU763_003785(doeB)
PALVKSS97_05935(doeB)
PZAHU749_024490(doeB)
PTAENCTC10697_00681
APRSBI364_02915
GAIIMCC3135_09910(doeB_2) IMCC3135_32270(doeB_4)
CSACsal_2731
HELHELO_3664(doeB)
HCSFF32_01825
HAKKO116_01204
HAMHALO1224
HHUAR456_15080
HCOLOKO_00472
HSIBOX17_04120
HALOBWR19_14480
HHHCLM76_01775(doeB)
HBEBEI_2958(doeB)
HAGBB497_00060
HAFC8233_14550(doeB)
HALKCUU95_10310(doeB)
HVNEI420_15840(doeB)
HOLHORIV_52440
HSRHSBAA_50400
HMDCTT34_14380(doeB)
HAXIHAALTHF_21770n
HTTHZS52_10960(doeB)
HCAMI4484_15855(doeB)
HPIZGYM47_13610(doeB)
HSXHNO51_15780(doeB)
HSVHNO53_16350(doeB)
HTXEKK97_17865(doeB)
HAAA5892_06420
CAMHLCW13_14025(doeB)
KUSB9G99_10905
KMAB9H00_03895
KUYFY550_04110(doeB)
PAURFGL86_17270(doeB)
ABOABO_0179
ADIB5T_00168
ALNAS19_01850
AXEP40_00825
OCEGU3_08060
ZDFAN401_02315
TSNW908_05910
THINCRN91_04520(doeB)
CBWRR42_s1931
BVIBcep1808_5461
BCNBcen_5802
BCHBcen2424_6166
BCMBcenmc03_6647
BCJBCAS0028
BCENDM39_6670(eutE)
BCEWDM40_5478(eutE)
BCEOI35_7027
BAMBamb_6021
BACBamMC406_5777
BMJBMULJ_05388
BMUBmul_6142
BMKDM80_6598(eutE)
BMULNP80_5359(eutE)
BCEDDM42_6399(eutE)
BDLAK34_5361(eutE)
BDFWI26_29880
BLATWK25_18055
BTEIWS51_29685
BPSLWS57_18490
BUGBC1001_4310
BGFBC1003_5086
BYIBYI23_B003720(eute)
BUEBRPE67_BCDS06290(eute)
BUQAC233_27925
BGPBGL_1c21000
BPLAbpln_1g19430
BXEBxe_C0058
BXBDR64_8367(eutE)
BPHBphy_3861
BGEBC1002_4847
BPXBUPH_00895
BFNOI25_3931(eutE)
BCAIK788_0000261
PSPWBJG93_22455(doeB)
PARABTO02_27260
PTERC2L65_27870(doeB)
PGPCUJ91_28290(doeB)
PTSCUJ90_21840(doeB)
PEWKZJ38_29860(doeB)
PPKU875_08125
PPNODA70_00835
PPNMLV28_05480
PRBX636_01500
PSPUNA29_09675
PVEUC34_18660
CABASBC2_38080(doeB)
BUOBRPE64_BCDS09540
BTRMSAMEA390648703342
ADYHLG70_08560
PARKLSG25_19950
VEIVeis_2148
JASFJQ89_08810
MTIMDIR46_02700
MFLAGO485_28205
APETToN1_21110(doeB)
ACOMCEW83_01830(doeB)
MLOmlr6093 mlr7142
MLNA9174_29920 A9174_31390 A9174_31775
MCIMesci_2508 Mesci_5716
MOPMesop_5920 Mesop_6295
MAMMesau_05392 Mesau_05768
MAMOA6B35_24250
MESWA9K65_013115 A9K65_030885 A9K65_031155
MESMEJ066_28920(doeB)
MESPC1M53_04390(doeB)
MHUAMCHK_0653(doeB)
MJREB229_30505(doeB) EB229_32015(doeB) EB229_32460
MERDEB233_26605(doeB)
MESRFGU64_08285(doeB)
HOEIMCC20628_03271
RPODE0E05_14120(doeB) E0E05_16220
ORMHTY61_13215(doeB)
KMNHW532_08410 HW532_10925(doeB)
SMESM_b20435(eutE)
SMKSinme_3745
SMQSinmeB_4241
SMXSM11_pD1187(eutE)
SMIBN406_06239
SMEGC770_GR4pD1176
SMELSM2011_b20435(eutE)
SMERDU99_31135
SMDSmed_3692
RHINGR_b23240
SFHSFHH103_04918
SFDUSDA257_c31400
SIXBSY16_5543(eutE)
SAMESAMCFNEI73_pC1834
SINOSS05631_b62070
EADOV14_b1417
EAHFA04_31175
ESJSJ05684_b43250
EAKEKH55_4171
EMXFKV68_31035(doeB) FKV68_31710(doeB)
ATUAtu4756
ATAAWN88_05990
AGRAGROH133_09406
ATFAch5_44880(doeB)
AROB0909_16550(doeB)
AGTEYD00_19135(doeB)
RETRHE_PF00179
RECRHECIAT_PC0000373
RELREMIM1_PF00737(eutE)
REPIE4803_PC00198(eutE)
REIIE4771_PD00199(eutE)
RLEpRL120055
RLTRleg2_5522
RLGRleg_5243
RLBRLEG3_09345
RLURLEG12_04780
RTRRTCIAT899_PC08135(eutE)
RIRBN877_II1095
RPUSCFBP5875_19345(doeB)
RHLLPU83_pLPU83d1325(eutE)
RGARGR602_PC02174(eutE)
RHNAMJ98_PE00273(eutE)
RPHAAMC79_PD00406(eutE)
RHXAMK02_PD00139(eutE)
RHVBA939_21240
RHKKim5_PC00183(eutE)
REZAMJ99_PD00273(eutE)
RJGCCGE525_32195(doeB)
RHRCKA34_29660(doeB)
RADCO657_26060(doeB)
ROYG3A56_16945(doeB)
RHIDFFM81_023125(doeB)
RBQJ2J99_22095(doeB)
RLNJ0663_22885(doeB)
RBANJ2J98_21080(doeB)
RRGJ3P73_24740(doeB)
NGLRG1141_PA13030(eutE)
NGGRG540_PA14010(eutE)
NEOCYG48_20835(doeB)
RHTNT26_3905
RFVRFYW14_03939
SHZshn_23135
SOJK6301_18980(doeB)
KAIK32_40600
BRJBKD03_11985
OINIAR37_18910(doeB)
BIOBR141012304_10757
OANOant_3466
OAHDR92_3020(eutE)
OPSA8A54_16020
OCHCES85_4624(eutE)
OCRHGK82_19820(doeB)
OCLGTN27_18045(doeB)
BOPAXW83_21155 AXW83_23735
BOSBSY19_1299
BVVBHK69_00420 BHK69_14640
BOIBLM15_05200 BLM15_23235
BOFFQV39_12920 FQV39_16740 FQV39_31510
LNEFZC33_33980(doeB)
APOLK9D25_11760(doeB)
MOCBB934_24605
MIVC4E04_03555 C4E04_10100(doeB)
CHELAL346_21855
CDQBOQ54_17550
DEQXM25_03290
YTIFNA67_07120
AALAIGS74_01710(doeB)
AALMLUX29_03030(doeB)
NOHG5V57_02545 G5V57_19980 G5V57_20165 G5V57_24780
LABPFJ695_10255(doeB)
PSTGE8M01_28135
ACUTMRB58_12635(doeB)
SILSPO1139(doeB)
SITTM1040_2694
JANJann_0849
RDERD1_3475
RLIRLO149_c026720
RPONG3256_07565(doeB)
OAROA238_c23680(eutE) OA238_c32660
LMDMETH_14370
LEJETW24_15265(doeB)
LAQUR2C4_20345(doeB)
CONTQ29_09650
SUAMBOO69_15090
SULDB5M07_16370
SPOTG6548_05615(doeB)
SMEDJNX03_02430(doeB)
SINLDSM14862_03216(doeB_2)
HATRC74_18040
RSQRsph17025_3178
CAZTLV780_15615(doeB)
PDEPden_0288
PYEA6J80_21900(doeB)
PZHCX676_02850(doeB)
PAROCUV01_01760(doeB)
PARSDRW48_07120(doeB)
PARREOJ32_08980(doeB)
PKDF8A10_17630(doeB)
PLIAE4191_06425(doeB)
PSANHGN31_00600(doeB)
PMAUCP157_01849(doeB)
RMBK529_013150
DAAAKL17_0185
DONBSK21_09535
LVSLOKVESSMR4R_00539(doeB)
SEDIEBB79_11110(doeB)
HMLHmaOT1_18510(doeB)
LITFPZ52_11030(doeB)
PAEDG5B38_20865
MONG8E03_07585(doeB)
HDHG5B40_08310(doeB) G5B40_08680
GCEKYE46_04385
HBAHbal_0924
PALGHFP57_02015
ATIAL072_17690
HTQFRZ44_47060
TXITH3_02585
THACCSC3H3_02840(doeB)
TIIDY252_18735(doeB)
ELIOKO353_13105
SNEANBZ79_05530(doeB)
PARHI5S86_22795(doeB)
PBKBack11_62870
PFAAMM59RIKEN_04930
LASAL9O85_11420
ETMCE91St48_29650
BPRSCK3_07620
AREAL755_13110
ARHAHiyo8_41630
RMLFF011L_02920
AAGGETAA8_28000 ETAA8_68890
PLSVT03_13335
PLHVT85_21860
FMRFuma_03204
GMRGmarT_14770
GIMF1728_07575
GPNPan110_14140
PLONPla110_12290
GESVT84_20975
GMSSOIL9_12590
TIMGMBLW1_22480
ULIETAA1_22410
SACISinac_6138
PBORBSF38_00443(doeB)
AGVOJF2_70140
PFERIRI77_06400
NSONIASO_04230
CAMUCA2015_2382
ECHIFKX85_16955
MARMYQ22_07400
AQDD1816_23735
FLGLV716_16405
HAADMW046_05110
NAYHYG81_00800
MEAMMU439_04650
 » show all
Reference
1  [PMID:20849449]
  Authors
Schwibbert K, Marin-Sanguino A, Bagyan I, Heidrich G, Lentzen G, Seitz H, Rampp M, Schuster SC, Klenk HP, Pfeiffer F, Oesterhelt D, Kunte HJ
  Title
A blueprint of ectoine metabolism from the genome of the industrial producer Halomonas elongata DSM 2581 T.
  Journal
Environ Microbiol 13:1973-94 (2011)
DOI:10.1111/j.1462-2920.2010.02336.x
  Sequence
[hel:HELO_3664]
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.125
IUBMB Enzyme Nomenclature: 3.5.1.125
ExPASy - ENZYME nomenclature database: 3.5.1.125
BRENDA, the Enzyme Database: 3.5.1.125
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