KEGG   ENZYME: 3.5.1.8
Entry
EC 3.5.1.8                  Enzyme                                 
Name
formylaspartate deformylase;
formylaspartic formylase (formylase I, formylase II)
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
Sysname
N-formyl-L-aspartate amidohydrolase
Reaction(IUBMB)
N-formyl-L-aspartate + H2O = formate + L-aspartate [RN:R00526]
Reaction(KEGG)
R00526
Substrate
N-formyl-L-aspartate [CPD:C01044];
H2O [CPD:C00001]
Product
formate [CPD:C00058];
L-aspartate [CPD:C00049]
History
EC 3.5.1.8 created 1961
Pathway
ec00340  Histidine metabolism
ec00630  Glyoxylate and dicarboxylate metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:13449063]
  Authors
OHMURA E, HAYAISHI O.
  Title
Enzymatic conversion of formylaspartic acid to aspartic acid.
  Journal
J Biol Chem 227:181-90 (1957)
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.8
IUBMB Enzyme Nomenclature: 3.5.1.8
ExPASy - ENZYME nomenclature database: 3.5.1.8
BRENDA, the Enzyme Database: 3.5.1.8
CAS: 9025-09-6
LinkDB

KEGG   REACTION: R00526
Entry
R00526                      Reaction                               
Name
N-formyl-L-aspartate amidohydrolase
Definition
N-Formyl-L-aspartate + H2O <=> Formate + L-Aspartate
Equation
C01044 + C00001 <=> C00058 + C00049
Reaction class
RC00165  C00049_C01044
RC00323  C00058_C01044
Enzyme
3.5.1.8         3.5.1.15
Pathway
rn00340  Histidine metabolism
rn00630  Glyoxylate and dicarboxylate metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.8
     R00526  N-Formyl-L-aspartate + H2O <=> Formate + L-Aspartate
    3.5.1.15
     R00526  N-Formyl-L-aspartate + H2O <=> Formate + L-Aspartate
IUBMB reaction hierarchy [BR:br08202]
 3. Hydrolase reactions
  3.5.1.15
   R00546  N-Acyl-L-aspartate <=> Carboxylate
    R00526  N-Formyl-L-aspartate <=> Formate
Orthology
K01437  aspartoacylase [EC:3.5.1.15]
Other DBs
RHEA: 22043
LinkDB

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