Entry
Name
(S)-ureidoglycine aminohydrolase;
UGlyAH;
UGHY;
ylbA (gene name)
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amidines
BRITE hierarchy
Sysname
(S)-ureidoglycine aminohydrolase
Reaction(IUBMB)
(S)-2-ureidoglycine + H2O = (S)-ureidoglycolate + NH3 [RN:
R05554 ]
Reaction(KEGG)
Substrate
(S)-2-ureidoglycine;
H2O [CPD:
C00001 ]
Product
Comment
Binds Mn2+. This enzyme, found in plants and bacteria, is part of the ureide pathway, which enables the recycling of the nitrogen in purine compounds. In plants it is localized in the endoplasmic reticulum.
History
EC 3.5.3.26 created 2013
Pathway
ec01120 Microbial metabolism in diverse environments
Orthology
K14977 (S)-ureidoglycine aminohydrolase
Genes
CSAT : 104718647 104723399 104731876
BNA : 106425359 106440141 106440260
HSYR : 120114237 120120380
MSYL : 126620035 126625674
SSPL : 121753531 121758529
PSOM : 113321920 113329962 113330063 113345874
TAES : 123039206 123052732 123188573
MFLO : 136542344 136552385
PVIR : 120661412 120688669
MIS : MICPUN_71152 MICPUN_97304
MAW : 19248669(J3458_005498)
CCAC : CcaHIS019_0105360(CcaverHIS019_0105360)
ECOO : ECRM13514_0321(ylbA)
ECOH : ECRM13516_0504(ylbA)
EDJ : ECDH1ME8569_0499(ylbA)
ECOI : ECOPMV1_00503(ylbA)
PAEB : NCGM1900_1455(ylbA)
CBER : B5D82_17180 B5D82_18870
GAI : IMCC3135_20530(allE)
NANI : NCTC12227_00791(ylbA)
REH : H16_B2457(h16_B2457)
BUO : BRPE64_CCDS02760(ylbA)
SFD : USDA257_c15150(ylbA)
NEN : NCHU2750_47550(ylbA)
OIN : IAR37_04935 IAR37_15780
METI : DK427_02955 DK427_04315
MMES : MMSR116_04175 MMSR116_06975
LAP : ACP90_16905 ACP90_23580
LABT : FIU93_01335 FIU93_23530
LAGG : B0E33_00320 B0E33_07040
YPAC : CEW88_14510 CEW88_19980
YAN : AYJ57_05480 AYJ57_16065
TPRO : Ga0080559_TMP2310 Ga0080559_TMP764
SINL : DSM14862_01470(allE)
SFAV : PL335_07570 PL335_16900
SPSE : SULPSESMR1_02899(allE) SULPSESMR1_04888(allE)
RMM : ROSMUCSMR3_02728(allE)
AHT : ANTHELSMS3_04160(allE)
PALX : GQA70_00130 GQA70_09810
PPAN : ESD82_02180 ESD82_15825
PDIM : PAF18_06865 PAF18_14555
DON : BSK21_02200 BSK21_09065
RBZ : B9057_04290 B9057_11350
LVS : LOKVESSMR4R_02829(allE)
RBG : BG454_00640 BG454_07875
PSEL : GM415_09130 GM415_17870
PTHE : LF599_03015(allE) LF599_04175(allE)
BSON : S101395_03701(ylbA)
SSIM : SAMEA4384339_0260(ylbA)
SSTE : SAMEA4384403_0161(ylbA)
WHJ : H9Q79_07435 H9Q79_07440
AMAU : DSM26151_07320(allE)
ASOI : MTP13_00105(allE) MTP13_00160 MTP13_07575(allE)
BALA : DSM104299_03327(allE)
» show all
Taxonomy
Reference
Authors
Serventi F, Ramazzina I, Lamberto I, Puggioni V, Gatti R, Percudani R
Title
Chemical basis of nitrogen recovery through the ureide pathway: formation and hydrolysis of S-ureidoglycine in plants and bacteria.
Journal
Sequence
Reference
Authors
Werner AK, Romeis T, Witte CP
Title
Ureide catabolism in Arabidopsis thaliana and Escherichia coli.
Journal
Sequence
Reference
Authors
Shin I, Percudani R, Rhee S
Title
Structural and functional insights into (S)-ureidoglycine aminohydrolase, key enzyme of purine catabolism in Arabidopsis thaliana.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.5.3.26
ExPASy - ENZYME nomenclature database: 3.5.3.26
LinkDB
All DBs