| Entry |
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| Name |
pyrithiamine deaminase;
1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium-bromide aminohydrolase
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| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In cyclic amidines
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| Sysname |
1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium aminohydrolase
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| Reaction(IUBMB) |
1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium + H2O = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium + NH3 [RN: R04641]
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| Reaction(KEGG) |
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| Substrate |
1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium [CPD: C21111];
H2O [CPD: C00001]
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| Product |
1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium [CPD: C21112];
NH3 [CPD: C00014]
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| History |
EC 3.5.4.20 created 1972, modified 2014
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| Reference |
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| Authors |
Sinha AK, Chatterjee GC. |
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| Title |
Metabolism of pyrithiamine by the pyrithiamine-requiring mutant of Staphylococcus aureus. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 3.5.4.20 |
| ExPASy - ENZYME nomenclature database: | 3.5.4.20 |
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| LinkDB |
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