KEGG   ENZYME: 3.6.1.20
Entry
EC 3.6.1.20                 Enzyme                                 
Name
5'-acylphosphoadenosine hydrolase;
5-phosphoadenosine hydrolase
Class
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
Sysname
5'-acylphosphoadenosine acylhydrolase
Reaction(IUBMB)
5'-acylphosphoadenosine + H2O = AMP + a carboxylate [RN:R00542]
Reaction(KEGG)
R00542 > R00322 R01423;
(other) R01690
Substrate
5'-acylphosphoadenosine [CPD:C03361];
H2O [CPD:C00001]
Product
AMP [CPD:C00020];
carboxylate [CPD:C00060]
Comment
Also acts on inosine and uridine compounds.
History
EC 3.6.1.20 created 1972
Pathway
ec00230  Purine metabolism
Reference
1  [PMID:13651188]
  Authors
KELLERMAN GM.
  Title
Isolation and characteristics of the enzyme acyl 5'-nucleotidase.
  Journal
Biochim Biophys Acta 33:101-5 (1959)
DOI:10.1016/0006-3002(59)90502-5
Other DBs
ExplorEnz - The Enzyme Database: 3.6.1.20
IUBMB Enzyme Nomenclature: 3.6.1.20
ExPASy - ENZYME nomenclature database: 3.6.1.20
BRENDA, the Enzyme Database: 3.6.1.20
CAS: 37289-31-9
LinkDB

KEGG   REACTION: R01423
Entry
R01423                      Reaction                               
Name
5'-benzoylphosphoadenosine benzoylhydrolase
Definition
5'-Benzoylphosphoadenosine + H2O <=> AMP + Benzoate
Equation
C06433 + C00001 <=> C00020 + C00180
Reaction class
RC00043  C00180_C06433
RC00070  C00020_C06433
Enzyme
3.6.1.20
Pathway
rn00230  Purine metabolism
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.20
     R01423  5'-Benzoylphosphoadenosine + H2O <=> AMP + Benzoate
IUBMB reaction hierarchy [BR:br08202]
 3. Hydrolase reactions
  3.6.1.20
   R00542  5'-Acylphosphoadenosine <=> Carboxylate
    R01423  5'-Benzoylphosphoadenosine <=> Benzoate
LinkDB

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