KEGG   ENZYME: 3.6.1.5
Entry
EC 3.6.1.5                  Enzyme                                 
Name
apyrase;
ATP-diphosphatase (ambiguous);
adenosine diphosphatase;
ADPase;
ATP diphosphohydrolase [ambiguous]
Class
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
Sysname
nucleoside triphosphate phosphohydrolase (nucleoside monophosphoate-forming)
Reaction(IUBMB)
a nucleoside 5'-triphosphate + 2 H2O = a nucleoside 5'-phosphate + 2 phosphate (overall reaction) [RN:R10443];
(1a) a nucleoside 5'-triphosphate + H2O = a nucleoside 5'-diphosphate + phosphate [RN:R02319];
(1b) a nucleoside 5'-diphosphate + H2O = a nucleoside 5'-phosphate + phosphate [RN:R10442]
Reaction(KEGG)
Substrate
nucleoside 5'-triphosphate [CPD:C00201];
H2O [CPD:C00001];
nucleoside 5'-diphosphate [CPD:C00454]
Product
nucleoside 5'-phosphate [CPD:C01117];
phosphate [CPD:C00009];
nucleoside 5'-diphosphate [CPD:C00454]
Comment
Apyrases are active against both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyse NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates. They differ from ATPases, which specifically hydrolyse ATP, by hydrolysing both ATP and ADP. The eukaryotic enzymes requires Ca2+, but Mg2+ can substitute. Most of the ecto-ATPases that occur on the cell surface and hydrolyse extracellular nucleotides belong to this enzyme family.
History
EC 3.6.1.5 created 1961, modified 1976, modified 2000, modified 2013
Pathway
ec00230  Purine metabolism
ec00240  Pyrimidine metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K01510  apyrase
K14641  apyrase
K14642  golgi apyrase
Genes
HSA377841(ENTPD8) 953(ENTPD1) 956(ENTPD3)
PTR100614135(ENTPD1) 460286(ENTPD3) 736974(ENTPD8)
PPS100971059(ENTPD1) 100983594(ENTPD3) 100995976(ENTPD8)
GGO101132716(ENTPD1) 101132747(ENTPD3) 109025377(ENTPD8)
PON100442938(ENTPD8) 100447406(ENTPD3) 100453241(ENTPD1)
NLE100579317(ENTPD3) 100598542(ENTPD8) 100605921(ENTPD1)
MCC704424(ENTPD8) 718311(ENTPD3)
MCF102132860(ENTPD1) 102134382(ENTPD8) 102138702(ENTPD3)
CSAB103216314(ENTPD1) 103227435(ENTPD3) 103239556(ENTPD8)
CATY105573869(ENTPD3) 105580636(ENTPD8) 105581766(ENTPD1)
PANU100998575(ENTPD8) 101002734(ENTPD1) 101020862(ENTPD3)
TGE112608133(ENTPD8) 112619016(ENTPD3) 112631446(ENTPD1)
RRO104659869(ENTPD3) 104664681(ENTPD1) 104669616(ENTPD8) 115900420
RBB108513116(ENTPD3) 108542831(ENTPD8) 108543811(ENTPD1)
TFN117069433(ENTPD1) 117083924(ENTPD3) 117099086(ENTPD8)
PTEH111538733(ENTPD1) 111553095(ENTPD8) 111555533(ENTPD3)
CJC100386711(ENTPD8) 100399270(ENTPD3)
SBQ101027723(ENTPD8) 101037434(ENTPD1) 101044080(ENTPD3)
CSYR103255971(ENTPD3) 103256299(ENTPD1) 103275022(ENTPD8)
MMUR105872734(ENTPD1) 105874405(ENTPD3) 105882244(ENTPD8)
LCAT123623415(ENTPD3) 123646125(ENTPD8) 123649686(ENTPD1)
OGA100942682(ENTPD1) 100959453(ENTPD8) 100965533(ENTPD3)
MMU12495(Entpd1) 215446(Entpd3) 72090(Entpd8)
MCAL110285484(Entpd1) 110302145(Entpd3) 110308986(Entpd8)
MPAH110319482(Entpd8) 110326188(Entpd1) 110328569(Entpd3)
RNO316077(Entpd3) 613267(Entpd8) 64519(Entpd1)
MCOC116072632(Entpd3) 116091880(Entpd8) 116103818(Entpd1)
MUN110546327(Entpd1) 110557023(Entpd8) 110566250(Entpd3)
CGE100755122(Entpd8) 100762593(Entpd1) 100772668(Entpd3)
MAUA101823414(Entpd3) 101833096(Entpd8) 101840694(Entpd1)
PLEU114681272(Entpd3) 114692762(Entpd8) 114706867(Entpd1)
MORG121454626(Entpd1) 121463045(Entpd8) 121464318(Entpd3)
AAMP119810736(Entpd3) 119815710(Entpd1) 119818500(Entpd8)
NGI103732585(Entpd8) 103733240(Entpd1) 103747123(Entpd3)
HGL101696417(Entpd3) 101708535(Entpd8) 101715301(Entpd1)
CPOC100717436(Entpd1) 100727694(Entpd8) 100733912(Entpd3)
CCAN109687369(Entpd8) 109693654(Entpd1) 109695130(Entpd3)
DORD105986747(Entpd1) 105995640(Entpd8) 105996228(Entpd3)
DSP122102137(Entpd8) 122115847(Entpd1) 122124881(Entpd3)
NCAR124964693 124969384 124984952 124985782
OCU100339644(ENTPD3) 100349881(ENTPD8) 100354213(ENTPD1)
OPI101523344(ENTPD1) 101524654(ENTPD8) 101528455(ENTPD3)
TUP102469337(ENTPD3) 102473460(ENTPD1) 102475046(ENTPD8)
CFA100688937(ENTPD8) 485604(ENTPD3) 486810(ENTPD1)
VVP112911431(ENTPD8) 112914147(ENTPD1) 112921630(ENTPD3)
VLG121472821(ENTPD8) 121479037(ENTPD3) 121484601(ENTPD1)
AML100468369(ENTPD8) 100473727(ENTPD3) 100474255(ENTPD1)
UMR103671702(ENTPD1) 103675256(ENTPD8) 103680467(ENTPD3)
UAH113248403 113248440 113251758(ENTPD1) 113253806(ENTPD3)
UAR123783982(ENTPD1) 123792811(ENTPD3) 123796298(ENTPD8)
ELK111145332 111146334 111159131
LLV125083779 125084557 125106160
MPUF101681262(ENTPD3) 101685170(ENTPD1) 101692262(ENTPD8)
ORO101362305(ENTPD1) 101366828(ENTPD3) 101377757(ENTPD8)
EJU114201758(ENTPD8) 114205283(ENTPD1) 114212359(ENTPD3)
ZCA113918801(ENTPD3) 113922513(ENTPD1) 113934599(ENTPD8)
MLX118002195(ENTPD3) 118017477(ENTPD8) 118024204(ENTPD1)
FCA101085582(ENTPD8) 101096356(ENTPD1) 101098083(ENTPD3)
PYU121020275(ENTPD8) 121033497(ENTPD3) 121037037(ENTPD1)
PBG122475464(ENTPD8) 122492125(ENTPD3) 122493064(ENTPD1)
PTG102953346(ENTPD8) 102960243(ENTPD1) 102962344(ENTPD3)
PPAD109248791(ENTPD3) 109260259(ENTPD8) 109264696(ENTPD1)
AJU106966707(ENTPD3) 106984805(ENTPD1) 106989063(ENTPD8)
HHV120222785(ENTPD8) 120230583(ENTPD1) 120235101(ENTPD3)
BTA282223(ENTPD1) 506087(ENTPD3) 515532(ENTPD8)
BOM102269229(ENTPD8) 102270483(ENTPD1) 102273587(ENTPD3)
BIU109553131(ENTPD1) 109576488(ENTPD3)
BBUB102391349(ENTPD3) 102408673(ENTPD8) 102415301(ENTPD1)
CHX102189182(ENTPD1) 102190080(ENTPD3) 108637182(ENTPD8)
OAS101107489(CC2D2B) 101114471(ENTPD3) 105612430(ENTPD8)
ODA120852232(ENTPD8) 120867789(ENTPD3) 120873735(ENTPD1)
CCAD122425069(ENTPD3) 122442431(ENTPD8) 122446091(ENTPD1)
SSC100516719(ENTPD8) 100623360(ENTPD3) 397298(ENTPD1)
CFR102503442(ENTPD1) 102509620(ENTPD3) 102520072(ENTPD8)
CBAI105061756(ENTPD3) 105073387(ENTPD8) 105081802(ENTPD1)
CDK105084264(ENTPD1) 105084627(ENTPD3) 105105103(ENTPD8)
VPC102534322(ENTPD8) 102534825(ENTPD1) 102543774(ENTPD3)
BACU103006116(ENTPD8) 103014786(ENTPD1) 103018820(ENTPD3)
LVE103069223(ENTPD3) 103078660(ENTPD1) 103080594(ENTPD8)
OOR101274730(ENTPD8) 101284487(ENTPD1) 101288931(ENTPD3)
DLE111169456(ENTPD3) 111172459(ENTPD1) 111176972(ENTPD8)
PCAD102974148(ENTPD1) 102981071(ENTPD8) 102996960(ENTPD3)
PSIU116741213(ENTPD1) 116756002(ENTPD8) 116761890(ENTPD3)
ECB100058558(ENTPD8) 100068004(ENTPD3) 100070956(ENTPD1)
EPZ103552666(ENTPD3) 103554172(ENTPD8) 103565822(ENTPD1)
EAI106822790(ENTPD8) 106842107(ENTPD1) 106842877(ENTPD3)
MYB102243699(ENTPD8) 102255350(ENTPD3) 102256383(ENTPD1)
MYD102752806(ENTPD1) 102755153(ENTPD8) 102774497(ENTPD3)
MMYO118655283(ENTPD8) 118668367(ENTPD3) 118669925(ENTPD1)
MLF102437086(ENTPD1) 102442174(ENTPD3)
MNA107524290(ENTPD3) 107536184(ENTPD8) 107542634(ENTPD1)
PKL118707030(ENTPD8) 118715516(ENTPD3) 118719330(ENTPD1)
HAI109380953(ENTPD1) 109381956(ENTPD8) 109393475(ENTPD3)
DRO112306209(ENTPD8) 112307065(ENTPD1) 112309626(ENTPD3)
SHON118976189(ENTPD3) 118980251(ENTPD8) 118990299(ENTPD1)
AJM119036079(ENTPD8) 119044506(ENTPD1) 119051522(ENTPD3)
PDIC114497534(ENTPD1) 114501680(ENTPD3) 114506946(ENTPD8)
PHAS123823442(ENTPD8) 123828879(ENTPD1) 123830567(ENTPD3)
MMF118629536(ENTPD8) 118632449(ENTPD1) 118633202(ENTPD3)
RFQ117031929(ENTPD8) 117035962(ENTPD1) 117037302(ENTPD3)
PALE102879249(ENTPD3) 102890548(ENTPD1) 102897950(ENTPD8)
PGIG120582192(ENTPD3) 120599738(ENTPD8) 120609269(ENTPD1)
PVP105290332(ENTPD3) 105298553(ENTPD8) 105301362(ENTPD1)
RAY107499639(ENTPD3) 107503102(ENTPD8) 107520403(ENTPD1)
MJV108394920(ENTPD1) 108396615(ENTPD8)
TOD119232986(ENTPD8) 119234573(ENTPD1) 119258357(ENTPD3)
SARA101539271(ENTPD3) 101545787(ENTPD1) 101554590(ENTPD8)
LAV100660160(ENTPD8) 100668440(ENTPD3) 100671741(ENTPD1)
TMU101351024 101351112 101352957
DNM101412553(ENTPD3) 101437959(ENTPD1) 101440603(ENTPD8)
MDO100022843(ENTPD8) 100022899(ENTPD1) 100023686 100025436(ENTPD3)
GAS123235132 123236337(ENTPD1) 123237191(ENTPD8) 123249738(ENTPD3)
SHR100914154(ENTPD1) 100919726(ENTPD8) 100926510(ENTPD3) 100932670
PCW110205253 110205289(ENTPD8) 110213157(ENTPD3) 110215401(ENTPD1)
OAA100078824(ENTPD3) 100086706(ENTPD1) 103168734 114807825
GGA374095(ENTPD8) 417281(ENTPD8L) 423826(ENTPD1) 427778 428447(ENTPD3)
PCOC116227146(ENTPD3) 116231740(ENTPD1) 116234124(ENTPD8) 116234125 116234420
MGP100543984(ENTPD1) 100546469 100547435 100547592 100550087(ENTPD3)
CJO107309259(ENTPD3) 107309321 107316066(ENTPD1) 107321667 107321669 107321671
NMEL110393876(ENTPD3) 110399890(ENTPD1) 110406879 110406881 110406882
APLA101795263 101795762 101796222 101801191(ENTPD1) 101804288(ENTPD3)
ACYG106037034 106037126(ENTPD8) 106037128 106037395(ENTPD1) 106046665(ENTPD3)
AFUL116486172(ENTPD3) 116491223(ENTPD1) 116496933(ENTPD8) 116497037 116497038
TGU100221575(ENTPD3) 100226299(ENTPD1) 100229162 105760940 115497587(ENTPD8)
LSR110468218(ENTPD3) 110472229 110472231 110472232 110473693(ENTPD1)
SCAN103812958(ENTPD3) 103813899(ENTPD1) 103819192 108962491 108962522(ENTPD8)
PMOA120502089(ENTPD1) 120504352(ENTPD3) 120507357 120507529 120507530
OTC121336903(ENTPD8) 121336905 121336971 121337629(ENTPD3) 121341855(ENTPD1)
PRUF121350169(ENTPD1) 121352991(ENTPD3) 121357544(ENTPD8) 121357545
GFR102034288(ENTPD3) 102040449(ENTPD8) 102040618 102040786 102043720(ENTPD1)
FAB101806865(ENTPD3) 101809481(ENTPD8) 101809685 101817605(ENTPD1) 101818198
PHI102099317(ENTPD3) 102105445 102107727(ENTPD8) 102110072(ENTPD1)
PMAJ107200959(ENTPD3) 107206906(ENTPD1) 107212208(ENTPD8) 107212235
CCAE111923529(ENTPD3) 111931219(ENTPD1) 111936903(ENTPD8)
CCW104688209 104688210 104688423 104689029(ENTPD3) 104696030(ENTPD1)
ETL114064140(ENTPD8) 114064394(ENTPD3) 114071077(ENTPD1)
ZAB102065192(ENTPD1) 102066915(ENTPD8) 102072513(ENTPD3) 106629640
FPG101912881(ENTPD3) 101915751(ENTPD1) 101918081 101918258 101918437(ENTPD8)
FCH102048208 102048554 102054936(ENTPD3) 106630880(ENTPD1) 114016622
CLV102083509 102083693 102095399(ENTPD1) 102096210(ENTPD8) 102097422(ENTPD3)
EGZ104123993 104123994 104124023(ENTPD8) 104127496(ENTPD3) 104129173(ENTPD1)
NNI104012854(ENTPD1) 104018481(ENTPD3) 104022425(ENTPD8) 104022754 104022765
PLET104615281(ENTPD1) 104618692 104620684(ENTPD3) 104625144 104625145
ACUN113477293(ENTPD3) 113481653(ENTPD1) 113486479 113486485 113486507
TALA104358206 104360844(ENTPD1) 104363868 104365752(ENTPD3) 116964210
PADL103916285(ENTPD1) 103917060(ENTPD3) 103921135 103921141
ACHC115335102 115335138 115335274(ENTPD8) 115339765(ENTPD3) 115348075(ENTPD1)
AAM106491248(ENTPD3) 106494220 106494222(ENTPD8) 106494269 106494711(ENTPD1)
AROW112964189(ENTPD1) 112965252 112965261 112967153(ENTPD3) 112969743(ENTPD8)
NPD112952665(ENTPD3) 112955911 112956104 112957029(ENTPD1)
DNE112982424(ENTPD3) 112986757(ENTPD8) 112986795 112986796 112989792(ENTPD1)
ASN102373368(ENTPD1) 102373540(ENTPD3) 102380815 102381055(ENTPD8) 102381801
AMJ102563980(ENTPD8) 102564208 102567238(ENTPD1) 102567497(ENTPD3) 106737136
CPOO109311123(ENTPD3) 109313792 109313796 109313797
GGN109291727(ENTPD3) 109292817 109292818 109292819
PSS102445405 102445643 102452816(ENTPD1) 102455639(ENTPD3) 102461628(ENTPD8)
CMY102934720(ENTPD3) 102946038(ENTPD8) 102946260 102946489 102947751(ENTPD1)
CPIC101944035 101946123 101946406(ENTPD8) 101948660(ENTPD1) 101952167(ENTPD3)
TST117867219(ENTPD8) 117867263 117872435(ENTPD3) 117880167(ENTPD1) 117889439
CABI116817690(ENTPD1) 116827004(ENTPD3) 116838103 116838107 116838108(ENTPD8)
MRV120369439(ENTPD1) 120386571 120386589 120386878 120398094(ENTPD3)
ACS100553564(entpd1) 100561052(entpd3) 103281931(entpd8)
PVT110082161(ENTPD3) 110082944(ENTPD8) 110084053(ENTPD1)
SUND121926680(ENTPD1) 121935261(ENTPD3) 121936619(ENTPD8)
PBI103052703(ENTPD3) 103053833(ENTPD1) 103066259(ENTPD8)
PMUR107287727(ENTPD1) 107294053(ENTPD3) 107296781(ENTPD8)
TSR106537856(ENTPD1) 106545487(ENTPD3) 106550196
PGUT117656100(ENTPD3) 117678569(ENTPD1)
VKO123016611(ENTPD3) 123026472(ENTPD1) 123035190(ENTPD8)
PMUA114589333(ENTPD8) 114597619(ENTPD1) 114607601(ENTPD3)
ZVI118084325(ENTPD8) 118092237(ENTPD3) 118093796(ENTPD1)
GJA107111486(ENTPD3) 107120421(ENTPD8) 107121141(ENTPD1)
STOW125437817(ENTPD1) 125441124(ENTPD3) 125441632(ENTPD8)
XLA108697462(entpd1.S) 108698845(entpd8.L) 108699877(entpd8.S) 443675(entpd3.L) 444164(entpd1.L)
XTR100125010(entpd3) 448501(entpd1) 733458(entpd8)
NPR108787246 108787250 108788349(ENTPD1) 108792068(ENTPD3)
RTEM120914061 120914062 120940285(ENTPD3) 120946766(ENTPD1)
BBUF120977389 120977413(ENTPD8) 121001222(ENTPD3) 121004358(ENTPD1)
BGAR122922116 122938712(ENTPD3) 122940173(ENTPD1) 122946420(ENTPD8) 122946629
DRE100005551(entpd3) 436652(entpd8) 445151(entpd1)
SRX107707825 107712074 107721165 107732432 107751912 107755533
SANH107657573 107667330 107673470 107684037 107702455 107704086
SGH107551200 107566185 107567076 107581561 107584429 107601661(entpd3)
CCAR109052575 109056122 109056659 109058905 109091317 109105721
CAUA113050429 113060097 113076924(entpd1) 113095378 113111587 113116178
PPRM120474605(entpd1) 120491267(entpd8) 120495099(entpd3)
MAMB125244153(entpd3) 125249132 125255114(entpd1) 125273805(entpd8)
IPU108268748(entpd3) 108271729(entpd8) 108274253(entpd1)
PHYP113527410(entpd1) 113527692 113533761(entpd3)
SMEO124383803(entpd8) 124384538(entpd3) 124388922(entpd1)
TFD113639005(entpd1) 113642807(entpd8) 113644187(entpd3)
AMEX103029336(entpd1) 103030351(entpd3) 103047612
EEE113575948 113577669(entpd1) 113581230(entpd3)
TRU101070429(entpd3)
TNGGSTEN00004166G001 GSTEN00035403G001
LCO104924305(entpd1) 104934031(entpd3)
NCC104941388(entpd1) 104952129(entpd3)
CGOB115021522 115024819(entpd1)
ELY117247163(entpd1) 117265750(entpd3)
PLEP121946172(entpd3) 121958628(entpd1)
SLUC116035307(entpd3) 116061094(entpd1)
ECRA117936832(entpd1) 117946626(entpd3)
PFLV114547886(entpd1) 114557293(entpd3)
GAT120811216(entpd3) 120819180(entpd1)
PPUG119197407(entpd3) 119212964(entpd1)
MSAM119897906(entpd3) 119915802(entpd1)
CUD121514258(entpd3) 121528024(entpd1)
ALAT119006496 119006497 119010113(entpd1)
MZE101473382 101487105(entpd1)
ONL100704242(entpd3) 100710562(entpd1)
OAU116322571(entpd3) 116328777(entpd1)
OLA101166588(entpd1)
OML112144083(entpd3) 112154116(entpd1)
XMA102217482(entpd1) 102226175(entpd3)
XCO114141799(entpd3) 114151957(entpd1)
XHE116717169(entpd3) 116726650(entpd1)
PRET103478359 103481559(entpd1)
PFOR103133663(entpd3) 103145114(entpd1)
PLAI106945013(entpd1) 106949550(entpd3)
PMEI106915170(entpd1) 106926238(entpd3)
GAF122823799(entpd1) 122831626(entpd3)
CVG107085557(entpd1) 107094107(entpd3)
CTUL119777117(entpd3) 119781925(entpd1)
GMU124866395(entpd3) 124875038(entpd1)
NFU107378765(entpd3) 107387774(entpd1)
KMR108232313(entpd3) 108249829(entpd1)
ALIM106514236(entpd3) 106516616(entpd1)
NWH119409514(entpd3) 119424042
AOCE111568276(entpd1) 111589170(entpd3)
CSEM103381648 103388765(entpd3)
POV109626952(entpd1) 109632099
SSEN122758898(entpd1) 122774223(entpd3)
HHIP117752556(entpd1) 117776652(entpd3)
HSP118100263(entpd1) 118113819(entpd3)
LCF108888779(entpd3) 108899023(entpd1)
SDU111220166(entpd1) 111227750(entpd3)
SLAL111655211(entpd1) 111655923(entpd3)
XGL120783689(entpd3) 120794669(entpd1)
HCQ109513373(entpd1) 109531055(entpd3)
BPEC110171693 110174579(entpd1)
MALB109958277 109962955
BSPL114842695(entpd3) 114845457(entpd1)
SASA106565347 106577463(entpd1) 106579923 106583547 106592522 106605417
OTW112215123 112222813 112228382 112239483(entpd1) 112254809(entpd8)
OMY110485980 110494099 110512886 110514391 110518781 110528323(entpd8)
OGO123996322 124003949 124004671 124020949(entpd1) 124029701
ONE115102836 115140957 115142115 115142972
SALP111959204 111964004 111964973 111970301 112076342
SNH120031668 120047188 120062834 120065313(entpd8)
ELS105016904(entpd8) 105025925(entpd3) 105026290(entpd1)
SFM108920199 108940459(entpd1) 108940642(entpd3)
PKI111836045(entpd1) 111840879(entpd3) 111848539
AANG118212342(entpd3) 118221372(entpd1) 118237352(entpd8)
LOC102687593(entpd2) 102688572(entpd1) 102693306(entpd3)
PSPA121306722(entpd8) 121308576 121313858 121321535 121325967(entpd1)
ARUT117394970 117396691 117400003 117415221 117417929(entpd1) 117964668
LCM102348651(ENTPD3) 102360392(ENTPD8) 102367063
CMK103181555 103181556 103181557 103182999 103183097 103183098 103189973(entpd1)
RTP109910493(entpd3) 109912690(entpd1)
BFO118413866
BBEL109478425
APLC110973950 110973952 110983083
SKO100368830
FOC113209845
TPAL117641665
FCD110845793
DMK116927395
PVM113817837
PJA122267704
PCHN125025655
HAME121862735
PTRU123518763
EAF111706209
LSM121122174
VDE111251791
VJA111267866
TUT107360652 107364935
DPTE113798542
DFR124489968
PTEP107453634
LGILOTGIDRAFT_114621
PCAN112565406
BGT106068536
GAE121384607
HRF124116889
HRJ124258299
CRG105337763
MYI110450013
PMAX117338745
MMER123547562
OBI106876002
OSN115229858
LAK106179978
SMMSmp_042020.1
SHXMS3_0012886
OVIT265_06976
EGLEGR_01343
NVE116619730
EPA110242461 110243230
ATEN116307007 116307079 116307083
ADF107336049 107336082
AMIL114969897 114969898 114976634
PDAM113665383 113667559 113671186 113686998
SPIS111331175 111337623 111341262
DGT114516040
XEN124444543
HMG100199550 105848299
AQU100640703 105313493
ATHAT1G14230 AT1G14240 AT1G14250 AT2G02970 AT3G04080(APY1) AT5G18280(APY2)
ALY110224709 9309949 9312922 9320493 9326107 9328859
CRB17882206 17885133 17887118 17891258 17898743 17899049
CSAT104706133 104710209 104712018 104735885 104740087 104743299 104744513 104755718 104755720 104755763 104764043 104770154 104779628 104780263 104790066 104793537
EUSEUTSA_v10003943mg EUTSA_v10007159mg EUTSA_v10007501mg EUTSA_v10007616mg EUTSA_v10007743mg EUTSA_v10009320mg EUTSA_v10013440mg EUTSA_v10020649mg
BRP103845846 103850057 103855214 103856882 103872117 103872118 103875454
BNA106346487 106346488 106369327 106383468 106387780 106391350 106401494 106402102 106411097 106430981 106430984 106435316 106441526 106445292
BOE106295085 106295086 106295939 106306759 106309614 106313338 106329707 106343588
RSZ108809982 108809984 108812996 108814597 108814863 108843009 108843219 108843931 108852144 108856226
THJ104802855 104805162 104824081 104827259
CPAP110809128 110810648 110818461
CIT102616215 102627845
CICCICLE_v10019963mg CICLE_v10031190mg
PVY116106057 116120713 116132828
MINC123209152 123209565 123217128 123221277
TCC18599959 18610398
GRA105764513 105782617 105783326 105804542
GHI107892437 107893168 107902190 107919991 107920112 107937027 107940657 107961896
GAB108464588 108464610 108474077 108479512
DZI111277090 111287650 111294171 111295974 111318343
EGR104433930 104442563 104453949
GMX100780748 100781628(GS52) 100784833 100786073 100787491 100804818 100806446 100807287 100811625 102665764
GSJ114382629 114383371 114386524 114390753 114390755 114391110 114391111 114400472 114403474 114411246
PVUPHAVU_001G096900g PHAVU_001G099900g PHAVU_001G100100g PHAVU_002G084900g PHAVU_006G017300g
VRA106753764 106753765 106753922 106773463 106774709 106777759
VAR108327837 108328030 108329048 108335803 108345811
VUN114173369 114173451 114182279 114188020 114190025
CCAJ109792790 109802056 109802912 109810473 109810487 109812807 109817023
APRC113857165 113861190 113861191 113861192 113866914 113868415
MTRMTR_5g040710 MTR_6g033000 MTR_7g085090 MTR_7g085120 MTR_7g085150 MTR_7g085180 MTR_7g085200
CAM101494121 101497346 101498578 101499461
LJALj0g3v0157119.1(Lj0g3v0157119.1) Lj0g3v0157119.2(Lj0g3v0157119.2) Lj1g3v3945990.1(Lj1g3v3945990.1) Lj1g3v3948060.1(Lj1g3v3948060.1) Lj2g3v1277850.1(Lj2g3v1277850.1)
ADU107470257 107470258 107471930 107489500 107494537
AIP107604923 107604924 107604925 107623054 107640592
AHF112697026 112697027 112716873 112750372 112754913 112754914 112754915 112784188 112801619
LANG109337182 109347590 109354843 109357095 109357816 109358598 109360758
FVE101293262 101304566
RCN112168464 112192862 112197346
PPER18770215 18789084
PMUM103321577 103330264 103338956
PAVI110751321 110766037 110770308
PDUL117613040 117632593 117634425
MDM103417106 103428652 103431911 103448163 103451818
PXB103950822 103956192
ZJU107404044 107410383 107434338
MNT21385727 21396851
CSV101203551 101220305
CMO103485786 103485970
BHJ120073155 120079810 120085487
MCHA111014161 111021140 111021142 111023164
CMAX111466003 111471351 111476496 111478226 111493176
CMOS111432518 111443276 111450763 111452272 111453301
CPEP111781513 111787584 111804389 111805724 111806048
RCU8260949 8268694 8281804
JCU105629332 105630441 105650422
HBR110638764 110642720 110652666 110655726 110657555 110657556
MESC110603485 110616353 110621087 110623614 110626848
POP18098053 18109412 7469858 7469860 7478588 7481587 7489644 7498171
PEU105107288 105107291 105112297 105117493 105120548 105132557 105139102
PALZ118032402 118036522 118038979 118043048 118054906 118054911 118062451
JRE108988782 109010565 109014015
QSU111988646 111995316 112016114 112029485 112033090 112038136
QLO115953594 115982692 115982805
TWL119993852 119997726 120001959 120002713 120008883
VVI100244785 100256492 100267968
VRI117914816 117916314 117916678
SLY101249402 101250072 101252471 101258050 101262543 101268182 109119465
SPEN107007410 107008956 107010762 107020755 107028796 107030775
SOT102577614(RROP1) 102577836(APY2) 102579107 102582098 102590497 102590620 102601329 102605146
CANN107846688 107847332 107849793 107850302 107851131 107851132
NTA107764352 107769955 107771380 107771917(APY1) 107774476 107783879 107786853 107798219 107815554 107817214
NSY104210731 104221379 104223629 104240806
NTO104108290 104109227 104110726 104114034 104116308
NAU109213050 109219199 109219741 109233140 109239449
INI109166353 109170022 109175203 109175205 109175206 109189763
ITR115996439 116015171 116015328 116017226 116017280 116025300 116030988
SIND105159965 105170629 105175913
OEU111366166 111366769 111372549 111396196 111403339
EGT105954018 105958239 105967630
SSPL121744475 121775216 121775276 121776092 121777520 121790147 121794828 121798092
HAN110895797 110898129 110899354 110921995 110926311 110926323 110939986
ECAD122582871 122585189 122585190 122595158
LSV111879065 111880034 111905368
CCAV112519278 112521063 112523319 112528677
DCR108193037 108209727 108219335
CSIN114258276 114270951 114270952 114275523 114279892 114314782
BVG104886770 104897915 104899915
SOE110782987 110783954 110798615
CQI110683512 110683796 110690376 110710331 110712568
NNU104589665 104589842 104597560 104598126
MING122063590 122068820 122081959 122086959
TSS122642973 122643901 122655790 122660161
PSOM113272711 113281677 113289759 113320151 113330582 113357165
NCOL116248661 116259942 116260295
OSA4332721 4332967 4344315 4345665 4349645 4349647 4350420 4351367
DOSAOs03t0378000-01(Os03g0378000) Os07t0682800-01(Os07g0682800) Os08t0436100-01(Os08g0436100) Os11t0125900-00(Os11g0125900) Os11t0126400-00(Os11g0126400) Os11t0439600-01(Os11g0439600) Os12t0123500-01(Os12g0123500)
OBR102699633 102708017 102710425 102711794 102716237 102718637
BDI100822906 100825383 100833921 100834806 100834835 100838315
ATS109733038 109734741 109734997 109735821 109746380 109752413 109754172 109756907 109762626
TDC119285580 119292160 119294307 119296272 119298558 119304250 119304351 119315112 119323185 119328027 119333632 119335237 119336348 119338413 119352725 119353246 119361740 119362367 119366809
TAES123039956 123039970 123043656 123048210 123051528 123076049 123085755 123089740 123089741 123092247 123093873 123097584 123099094 123099191 123106054 123106157 123132149 123136181 123143692 123152142 123159880 123161121 123161973 123162531 123166681 123184231 123187448
TUA125506520 125506521 125511510 125513180 125525001 125528082 125530403 125532056 125535039 125535614 125551531
SBI8067142 8067632 8071608 8074461 8075671 8076917 8080757 8083035 8084559
ZMA100272244 100273224 100273583 100281594 100381419 103634608 103647945 103647994 103654305
SITA101757382 101764324 101769705 101770111 101772875 101775667 101786001
SVS117833785 117833786 117836692 117840082 117845404 117861250 117865831
PVIR120640972 120643891 120643954 120643955 120643957 120652209 120652492 120662197 120677730 120686063 120688382 120689802 120694878 120712452
PHAI112873171 112874135 112880023 112897031 112902787 112902788
PDA103702194 103709080 103709110 103709688 103716401 103718805
EGU105041734 105044896 105046067 105046068 105046103 105057256 105058311
MUS103973994 103982847 103984193 103989659 103992480 103996977 103997392
DCT110098759 110107178 110108621 110110514
PEQ110019482 110025448 110028934 110032940
AOF109832566 109848171 109849711
ATR18422232 18425173 18433580
SMOSELMODRAFT_183978(APY-2) SELMODRAFT_233281(APY-1) SELMODRAFT_63506 SELMODRAFT_94922
PPP112273447 112273613 112276037 112276123 112286663
CRECHLRE_03g184800v5 CHLRE_06g273500v5 CHLRE_07g330600v5
VCNVOLCADRAFT_120373 VOLCADRAFT_78871 VOLCADRAFT_91259
MNGMNEG_9783
CSLCOCSUDRAFT_28740
APROF751_5931
OLUOSTLU_36812
OTAOT_ostta04g01140
BPGBathy03g01520 Bathy12g03540
MISMICPUN_84198 MICPUN_87507
MPPMICPUCDRAFT_32900
SCEYER005W(YND1)
SEUBDI49_1399
SPAOSPAR_E00740
AGOAGOS_ADR006W
ERCEcym_4478
KLAKLLA0_D13662g
KMXKLMA_50381(YND1)
LTHKLTH0F13178g
VPOKpol_312p10
ZROZYRO0D09570g
CGRCAGL0H09746g
NCSNCAS_0I00760(NCAS0I00760)
NDINDAI_0A08280(NDAI0A08280)
TPFTPHA_0L00770(TPHA0L00770)
TBLTBLA_0A01060(TBLA0A01060)
TDLTDEL_0H03120(TDEL0H03120)
TGBHG536_0F03230
KAFKAFR_0L00600(KAFR0L00600)
KNGKNAG_0L00790(KNAG0L00790)
ZMKHG535_0F02590
PPAPAS_chr1-1_0063 PAS_chr2-2_0017
DHADEHA2A10098g DEHA2D16764g
PICPICST_75213(YND1) PICST_85565(YND2)
PGUPGUG_00627 PGUG_01992
SPAASPAPADRAFT_61967 SPAPADRAFT_69800
LELLELG_02860 LELG_04414
CALCAALFM_C406230CA(CaO19.2915)
CTPCTRG_04045
COTCORT_0C04840 CORT_0E01960
CDUCD36_45750
CTENCANTEDRAFT_111440 CANTEDRAFT_126815
YLIYALI0A00913g YALI0C19712g
CLUCLUG_01050 CLUG_04769
CLUSA9F13_09g00968 A9F13_11g00242
CAURCJI97_000930 CJI97_002281
SLBAWJ20_3098(YND1) AWJ20_650(YND1)
PKZC5L36_0C02780
BNNFOA43_001646 FOA43_002248
BBRXBRETT_004858 BRETT_005021
OPAHPODL_01487 HPODL_02355
SLUDSCDLUD_005183
NCRNCU08027
NTENEUTE1DRAFT79731(NEUTE1DRAFT_79731)
SMPSMAC_03806
PANPODANSg7327
TTTTHITE_66668
MTMMYCTH_2314148
CTHRCTHT_0033950
MGRMGG_07077
PPEIPpBr36_01707
TMNUCRPA7_547
SSCKSPSK_07107
FGRFGSG_04270
FPUFPSE_10473
FVRFVEG_10460
FOXFOXG_11355
NHENECHADRAFT_81390
TRETRIREDRAFT_55114(trre33435)
TRRM419DRAFT_126703
MAWMAC_09286
MAJMAA_02713
CMTCCM_00441
PLJVFPFJ_08897
VALVDBG_08237
VDAVDAG_10433
CFJCFIO01_00504
CHIGCH63R_07703
SAPOSAPIO_CDS0867
ELAUCREL1_4078
PFYPFICI_05697
SSLSS1G_08469
BFUBCIN_12g02700
MBEMBM_06708
PSCOLY89DRAFT_399990
GLZGLAREA_10643
ANIAN0210.2
AFMAFUA_5G11010
ACTACLA_014050
NFINFIA_076250
AORAO090026000750
ANGANI_1_362124(An14g02370)
AFVAFLA_005534
ALUCAKAW2_40922A(YND1)
ACHEACHE_41091A(YND1)
APUUAPUU_11932A(YND1)
PCSPc21g11060
PDPPDIP_57120
TMFPMAA_033270
TRGTRUGW13939_05557
CIMCIMG_00679
CPWCPC735_055920
UREUREG_00676
PBLPAAG_02328
PBNPADG_05467
ABEARB_03010
TVETRV_01726
AJEHCAG_00911
BGHBDBG_01088
PNOSNOG_08875
PTEPTT_04005
BZECOCCADRAFT_8703
BSCCOCSADRAFT_214433
BORCOCMIDRAFT_558
AALTCC77DRAFT_1020560
ZTRMYCGRDRAFT_101192
PFJMYCFIDRAFT_157197
FFUCLAFUR5_11570
BCOMBAUCODRAFT_311656
NPAUCRNP2_6519
TMLGSTUM_00004360001
SPOSPCC11E10.05c(ynd1)
CNECNF00290
CNBCNBF4410
CNGCNAG_07692
CGICGB_F6320W
TMSTREMEDRAFT_35565
TASAA1Q1_04439
PPLPOSPLDRAFT_106702
TVSTRAVEDRAFT_145439
DSQDICSQDRAFT_78440
PCOPHACADRAFT_255752
SHSSTEHIDRAFT_42442
HIRHETIRDRAFT_60065
PSQPUNSTDRAFT_71457
ADLAURDEDRAFT_180697
FMEFOMMEDRAFT_46305
GTRGLOTRDRAFT_114425
LBCLACBIDRAFT_238748
MRRMoror_2733
MOREE1B28_009222
CCICC1G_01031
SCMSCHCODRAFT_43885
ABPAGABI1DRAFT117868(AGABI1DRAFT_117868)
ABVAGABI2DRAFT182942(AGABI2DRAFT_182942)
CPUTCONPUDRAFT_162097
SLASERLADRAFT_417574
WSEWALSEDRAFT_66984
WICJ056_004335
UMAUMAG_00987
PFPPFL1_01049
MGLMGL_2670
MRTMRET_2664
MSYMMSY001_0177
PGRPGTG_08877
MLRMELLADRAFT_48465
MBRMONBRDRAFT_28117
SREPTSG_00014
TETTTHERM_00129300 TTHERM_00684480 TTHERM_01256510
PTMGSPATT00024160001 GSPATT00031501001 GSPATT00035597001 GSPATT00037111001
SMINv1.2.033068.t1(symbB.v1.2.033068.t1) v1.2.033768.t1(symbB.v1.2.033768.t1)
AAFAURANDRAFT_52656
EHXEMIHUDRAFT_208241 EMIHUDRAFT_52732 EMIHUDRAFT_52751
TVATVAG_095420 TVAG_167570 TVAG_275500 TVAG_456510
 » show all
Reference
1  [PMID:14953432]
  Authors
KRISHNAN PS.
  Title
Apyrase, pyrophosphatase and metaphosphatase of Penicillium chrysogenum.
  Journal
Arch Biochem 37:224-34 (1952)
DOI:10.1016/0003-9861(52)90180-X
Reference
2  [PMID:13930517]
  Authors
LIEBECQ C, LALLEMAND A, DEGUELDRE-GUILLAUME MJ
  Title
[Partial purification and properties of potato apyrase.]
  Journal
Bull Soc Chim Biol (Paris) 45:573-94 (1963)
Reference
3  [PMID:3038893]
  Authors
Chen YR, Datta N, Roux SJ
  Title
Purification and partial characterization of a calmodulin-stimulated nucleoside triphosphatase from pea nuclei.
  Journal
J Biol Chem 262:10689-94 (1987)
Reference
4  [PMID:8529670]
  Authors
Christoforidis S, Papamarcaki T, Galaris D, Kellner R, Tsolas O
  Title
Purification and properties of human placental ATP diphosphohydrolase.
  Journal
Eur J Biochem 234:66-74 (1995)
DOI:10.1111/j.1432-1033.1995.066_c.x
  Sequence
[hsa:953]
Reference
5  [PMID:8626624]
  Authors
Wang TF, Guidotti G
  Title
CD39 is an ecto-(Ca2+,Mg2+)-apyrase.
  Journal
J Biol Chem 271:9898-901 (1996)
DOI:10.1074/jbc.271.17.9898
  Sequence
[hsa:953]
Reference
6  [PMID:10409709]
  Authors
Gao XD, Kaigorodov V, Jigami Y
  Title
YND1, a homologue of GDA1, encodes membrane-bound apyrase required for Golgi N- and O-glycosylation in Saccharomyces cerevisiae.
  Journal
J Biol Chem 274:21450-6 (1999)
DOI:10.1074/jbc.274.30.21450
  Sequence
[sce:YER005W]
Reference
7  [PMID:15576788]
  Authors
Xu W, Jones CR, Dunn CA, Bessman MJ
  Title
Gene ytkD of Bacillus subtilis encodes an atypical nucleoside triphosphatase member of the Nudix hydrolase superfamily.
  Journal
J Bacteriol 186:8380-4 (2004)
DOI:10.1128/JB.186.24.8380-8384.2004
  Sequence
[bsu:BSU30630]
Other DBs
ExplorEnz - The Enzyme Database: 3.6.1.5
IUBMB Enzyme Nomenclature: 3.6.1.5
ExPASy - ENZYME nomenclature database: 3.6.1.5
BRENDA, the Enzyme Database: 3.6.1.5
CAS: 9000-95-7
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