KEGG   ENZYME: 3.6.2.2
Entry
EC 3.6.2.2                  Enzyme                                 
Name
phosphoadenylylsulfatase;
3-phosphoadenylyl sulfatase;
3-phosphoadenosine 5-phosphosulfate sulfatase;
PAPS sulfatase;
3'-phosphoadenylylsulfate sulfohydrolase
Class
Hydrolases;
Acting on acid anhydrides;
In sulfonyl-containing anhydrides
Sysname
3'-phosphoadenylyl-sulfate sulfohydrolase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + H2O = adenosine 3',5'-bisphosphate + sulfate [RN:R00507]
Reaction(KEGG)
R00507
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
H2O [CPD:C00001]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
sulfate [CPD:C00059]
Comment
Requires Mn2+.
History
EC 3.6.2.2 created 1972
Pathway
ec00230  Purine metabolism
ec00920  Sulfur metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:13864264]
  Authors
BALASUBRAMANIAN AS, BACHHAWAT BK.
  Title
Enzymic degradation of active sulphate.
  Journal
Biochim Biophys Acta 59:389-97 (1962)
DOI:10.1016/0006-3002(62)90188-9
Other DBs
ExplorEnz - The Enzyme Database: 3.6.2.2
IUBMB Enzyme Nomenclature: 3.6.2.2
ExPASy - ENZYME nomenclature database: 3.6.2.2
BRENDA, the Enzyme Database: 3.6.2.2
CAS: 37289-37-5
LinkDB

KEGG   REACTION: R00507
Entry
R00507                      Reaction                               
Name
3'-phosphoadenylyl-sulfate sulfohydrolase;
3'-phosphoadenylyl-sulfate nucleotidohydrolase
Definition
3'-Phosphoadenylyl sulfate + H2O <=> Sulfate + Adenosine 3',5'-bisphosphate
Equation
C00053 + C00001 <=> C00059 + C00054
Reaction class
RC00007  C00053_C00054
Enzyme
3.6.2.2
Pathway
rn00230  Purine metabolism
rn00920  Sulfur metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.6  Acting on acid anhydrides
   3.6.2  In sulfonyl-containing anhydrides
    3.6.2.2
     R00507  3'-Phosphoadenylyl sulfate + H2O <=> Sulfate + Adenosine 3',5'-bisphosphate
Other DBs
RHEA: 11235
LinkDB

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