| Entry |
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| Name |
acetoacetate decarboxylase;
acetoacetic acid decarboxylase;
acetoacetate carboxy-lyase
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| Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
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| Sysname |
acetoacetate carboxy-lyase (acetone-forming)
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| Reaction(IUBMB) |
acetoacetate + H+ = acetone + CO2 [RN: R01366]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| History |
EC 4.1.1.4 created 1961
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| Pathway |
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| Orthology |
| K01574 | acetoacetate decarboxylase |
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| Genes |
| OSG: | BST96_08300 BST96_14785 |
| HJA: | BST95_04415 BST95_09935 |
| HALC: | EY643_12670 EY643_18075 |
| LSH: | CAB17_07330 CAB17_13380 |
| LJR: | NCTC11533_02131(adc) |
| LCJ: | NCTC11976_01373(adc) |
| LWA: | SAMEA4504053_0998(adc) |
| LSS: | NCTC12082_00433(adc) |
| LADL: | NCTC12735_00965(adc) |
| LANT: | TUM19329_28970(adc) |
| FTD: | AS84_1732 AS84_221(adc) |
| BVI: | Bcep1808_3777 Bcep1808_4583 |
| BUR: | Bcep18194_B1397 Bcep18194_B3166 |
| BAC: | BamMC406_3126 BamMC406_5563 |
| BCEP: | APZ15_24935 APZ15_36175 |
| BPYR: | ABD05_21330 ABD05_30610 |
| BLAT: | WK25_15965 WK25_19575 |
| BSTG: | WT74_20460 WT74_24130 |
| BURK: | DM992_22035 DM992_26110 DM992_34560 |
| BPY: | Bphyt_1567 Bphyt_2412 |
| BUZ: | AYM40_23020 AYM40_28035 |
| BCAI: | K788_0000336 K788_0005690 |
| PHS: | C2L64_26230 C2L64_27150 |
| PTER: | C2L65_22200 C2L65_28160 |
| PACP: | FAZ97_23835 FAZ97_28595 |
| PEW: | KZJ38_25620 KZJ38_33460 |
| PDIO: | PDMSB3_0240.1 PDMSB3_1576 |
| BTRM: | SAMEA390648701655(adc) |
| MLO: | mll5917 mlr2399 mlr3634 |
| MLN: | A9174_07425 A9174_32420 |
| MESP: | C1M53_17115 C1M53_17410 |
| MJR: | EB229_07635 EB229_33140 |
| MERD: | EB233_07550 EB233_30785 |
| SFD: | USDA257_c17320 USDA257_c17360 |
| RII: | FFM53_006555 FFM53_034345 |
| BJA: | bll7763(bll7763) blr3945(blr3945) blr7028(blr7028) |
| BJU: | BJ6T_16150 BJ6T_58910 BJ6T_62570 |
| BJP: | RN69_07975 RN69_30325 |
| BRAD: | BF49_0522 BF49_1107 |
| BRK: | CWS35_01220 CWS35_27820 |
| BOT: | CIT37_17685 CIT37_22400 CIT37_34260 CIT37_35815 |
| BEL: | BE61_63130 BE61_85850 BE61_87570 |
| BSEP: | HAP48_0021020 HAP48_0022790 HAP48_0034650 |
| BQB: | J4P68_0003745 J4P68_0013070 J4P68_0017465 |
| VGO: | GJW-30_1_03383(adc_1) GJW-30_1_03970(adc_2) |
| TRB: | HB776_20345 HB776_20960 |
| BOF: | FQV39_15580 FQV39_29260 |
| XDI: | EZH22_06805 EZH22_22120 |
| MAQU: | Maq22A_2p40725 Maq22A_c24380(adc) |
| MOC: | BB934_02595 BB934_11530 BB934_31395 BB934_36525 |
| MTUN: | MTUNDRAET4_2027(adc) |
| RHZ: | RHPLAN_16330 RHPLAN_31430 |
| PSTG: | E8M01_28145 E8M01_28150 |
| BLAS: | BSY18_3376 BSY18_3377 |
| BFW: | B5J99_07755 B5J99_07760 |
| HTQ: | FRZ44_16710(adc2) FRZ44_20890 |
| VNE: | CFK40_04275 CFK40_04285 |
| PPM: | PPSC2_06055(adc1) PPSC2_12620(adc3) |
| PPO: | PPM_1145(adc1) PPM_2419(adc3) |
| PPOY: | RE92_05830 RE92_24155 |
| PRI: | PRIO_0485(adc) PRIO_1671 |
| MBAI: | MB901379_04218(adc) |
| MHEK: | JMUB5695_04669(adc) |
| SCT: | SCAT_p0752(adc) SCAT_p1328(adc) |
| SCY: | SCATT_p03950 SCATT_p09870 |
| STRE: | GZL_06678 GZL_08372 |
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| Reference |
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| Authors |
Davies R. |
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| Title |
Studies on the acetone-butanol fermentation: 4. Acetoacetic acid decarboxylase of Cl. acetobutylicum (BY). |
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| Journal |
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| Reference |
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| Authors |
Zerner B, Coutts SM, Lederer F, Waters HH, Westheimer FH. |
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| Title |
Acetoacetate decarboxylase. Preparation of the enzyme. |
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| Journal |
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| Reference |
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| Authors |
Ho MC, Menetret JF, Tsuruta H, Allen KN |
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| Title |
The origin of the electrostatic perturbation in acetoacetate decarboxylase. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.1.1.4 |
| ExPASy - ENZYME nomenclature database: | 4.1.1.4 |
| BRENDA, the Enzyme Database: | 4.1.1.4 |
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| LinkDB |
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