KEGG   ENZYME: 4.2.1.134
Entry
EC 4.2.1.134                Enzyme                                 
Name
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase;
PHS1 (gene name);
PAS2 (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
very-long-chain (3R)-3-hydroxyacyl-CoA hydro-lyase
Reaction(IUBMB)
a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain trans-2,3-dehydroacyl-CoA + H2O [RN:R10827]
Reaction(KEGG)
R10827;
(other) R07760
Substrate
very-long-chain (3R)-3-hydroxyacyl-CoA [CPD:C20878]
Product
very-long-chain trans-2,3-dehydroacyl-CoA [CPD:C20879];
H2O [CPD:C00001]
Comment
This is the third component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long chain acyl CoAs. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase.
History
EC 4.2.1.134 created 2012, modified 2014
Pathway
ec00062  Fatty acid elongation
ec01040  Biosynthesis of unsaturated fatty acids
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K10703  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
Genes
HSA201562(HACD2) 401494(HACD4) 51495(HACD3) 9200(HACD1)
PTR450331(HACD1) 744160(HACD4) 746499(HACD2) 747950(HACD3)
PPS100970660(HACD1) 100979084(HACD2) 100986064(HACD3) 100995506(HACD4)
GGO101127709(HACD3) 101136535(HACD4) 101151156(HACD2) 109028458(HACD1)
PON100172398(HACD2) 100174644(HACD3) 100442069(HACD4) 100446614(HACD1)
NLE100590465(HACD2) 100599328(HACD4) 100604226(HACD3) 100606599(HACD1)
MCC700635(HACD1) 709590(HACD3) 711051(HACD4) 715374(HACD2)
MCF101865117(HACD3) 102117284(HACD4) 102127341(HACD1) 102134779(HACD2)
CSAB103219384(HACD4) 103228165(HACD2) 103237958(HACD1) 103245466(HACD3)
CATY105583829(HACD1) 105584003(HACD4) 105589788(HACD2) 105600999(HACD3)
PANU101005265(HACD3) 101012739(HACD1) 101015194(HACD2) 101024877(HACD4)
TGE112608746(HACD4) 112619076(HACD2) 112627753(HACD3) 112631000(HACD1)
RRO104655329(HACD1) 104655408(HACD2) 104655951(HACD3) 104670296(HACD4)
RBB108514704(HACD3) 108517427(HACD2) 108527749(HACD1) 108538566(HACD4)
TFN117070488(HACD3) 117082344(HACD1) 117083397(HACD2) 117098636(HACD4)
PTEH111526144(HACD4) 111544357(HACD2) 111548364(HACD3) 111550018(HACD1)
CJC100387676(HACD4) 100408770(HACD1) 100412428(HACD2) 100413343(HACD3)
SBQ101033969(PTPLAD1) 101036309(PTPLAD2) 101046641 101050076(PTPLB)
CSYR103255144(HACD3) 103258681(HACD1) 103260913(HACD4)
MMUR105862394(HACD1) 105868108(HACD3) 105869754 105874187(HACD4) 105879867(HACD2)
LCAT123625679(HACD1) 123630470(HACD2) 123631477(HACD3) 123646237(HACD4)
OGA100949870(HACD1) 100955721(HACD3) 100955886(HACD2) 100959701(HACD4)
MMU30963(Hacd1) 57874(Hacd3) 66775(Hacd4) 70757(Hacd2)
MCAL110289622(Hacd1) 110293501(Hacd4) 110302041(Hacd3) 110311618(Hacd2)
MPAH110318642(Hacd1) 110323573(Hacd4) 110327686(Hacd3) 110329705(Hacd2)
RNO300783(Hacd3) 362540(Hacd4) 680115(Hacd1)
MCOC116073382(Hacd3) 116085854(Hacd2) 116090877(Hacd1) 116096217(Hacd4)
MUN110547241(Hacd2) 110556033 110556034 110561772(Hacd1) 110563421(Hacd4)
CGE100752449(Hacd3) 100765668(Hacd2) 100772448(Hacd1) 100774830(Hacd4)
MAUA101824264(Hacd4) 101827492(Hacd2) 101828198(Hacd3) 101833869(Hacd1)
PLEU114685159(Hacd4) 114691426(Hacd3) 114693936(Hacd1) 114704842(Hacd2)
MORG121432642(Hacd1) 121448039(Hacd4) 121461820(Hacd2) 121466063(Hacd3)
AAMP119809027(Hacd3) 119816780(Hacd1) 119817072(Hacd4) 119824791(Hacd2)
NGI103734827(Hacd1) 103736789(Hacd3) 103741991(Hacd2) 103743953(Hacd4)
HGL101698416(Hacd4) 101703393(Hacd2) 101718268(Hacd1) 101719524(Hacd3)
CPOC100713755(Hacd4) 100714453(Hacd2) 100714636(Hacd3) 100723879(Hacd1)
CCAN109692334(Hacd3) 109697197(Hacd4) 109697405(Hacd1) 109701080(Hacd2)
DORD105980923(Hacd3) 105984460(Hacd1) 105987991(Hacd2) 105988991(Hacd4)
DSP122097313(Hacd2) 122113176(Hacd1) 122114496(Hacd3) 122118939(Hacd4)
NCAR124962181 124964321 124976065 124993148
OCU100339262(HACD3) 100343182(HACD4) 100346386(HACD1) 100352022(HACD2)
OPI101523165(HACD2) 101523576(HACD1) 101528384(HACD4) 101536305(HACD3)
TUP102477817(HACD1) 102479872(HACD3) 102490208(HACD2) 102497590(HACD4)
CFA478345(HACD3) 574011(HACD1) 608764(HACD2) 611337(HACD4)
VVP112913505(HACD2) 112922016(HACD4) 112927718(HACD3) 112932948(HACD1)
VLG121484235(HACD3) 121494346(HACD4) 121498003(HACD1) 121500674(HACD2)
AML100464409(HACD1) 100476116(HACD3) 100476304(HACD4) 100482012(HACD2)
UMR103662151(HACD4) 103664207(HACD1) 103678825(HACD2) 103679073(HACD3)
UAH113240874(HACD3) 113241365(HACD1) 113252377(HACD2) 113260582(HACD4)
UAR123781087(HACD4) 123785709(HACD1) 123800777(HACD3) 123802200(HACD2)
ELK111153279 111155146 111155584 111156576
LLV125083788 125103278 125104081 125106448
MPUF101672443(HACD1) 101678207(HACD2) 101679392(HACD4) 101686296(HACD3)
ORO101365326(HACD3) 101375190(HACD4) 101380540(HACD2) 101382579(HACD1)
EJU114199419(HACD2) 114206410(HACD3) 114212403(HACD4) 114217315(HACD1)
ZCA113909520(HACD3) 113916855(HACD2) 113922773(HACD1) 113934418(HACD4)
MLX117999021(HACD4) 118003594(HACD3) 118007015(HACD2) 118021528(HACD1)
FCA101084111(HACD3) 101088195(HACD4) 101092752(HACD1) 101100993(HACD2)
PYU121014756(HACD1) 121034516(HACD4) 121036342(HACD2) 121041854(HACD3)
PBG122468499(HACD3) 122473990(HACD1) 122474496(HACD4) 122491525(HACD2)
PTG102949189(HACD2) 102960714(HACD4) 102962823(HACD3) 102968266(HACD1)
PPAD109247052(HACD4) 109262830(HACD3) 109266497(HACD2) 109273678(HACD1)
AJU106971054(HACD4) 106979880(HACD1) 106980190(HACD3) 106984070(HACD2)
HHV120221617(HACD3) 120237363(HACD2) 120239876(HACD4) 120240982(HACD1)
BTA100125237(HACD3) 613886(HACD2) 615191(HACD1) 618814(HACD4)
BOM102266008(HACD3) 102269541(HACD2) 102280214(HACD4) 102283288(HACD1)
BIU109555850(HACD2) 109562856(HACD4) 109564690(HACD3) 109567983(HACD1)
BBUB102391829(HACD3) 102403025(HACD4) 102405071(HACD2) 102415760(HACD1)
CHX102170231(HACD4) 102183078(HACD1) 102186599(HACD3) 102190073(HACD2)
OAS101102210(HACD4) 101120135(HACD2) 101120835(HACD3) 114117470 443484(HACD1)
ODA120852539(HACD3) 120862269(HACD4) 120869041(HACD1) 120870695(HACD2)
CCAD122443049(HACD3) 122444645(HACD2) 122448495(HACD1) 122453233(HACD4)
SSC100154613(HACD3) 100523084(HACD1) 100523711(HACD4) 102158186(HACD2)
CFR102503531(HACD2) 102513006(HACD3) 102517774(HACD4) 102522520(HACD1)
CBAI105061882(PTPLAD2) 105069291(PTPLAD1) 105078409(PTPLA) 105081636(PTPLB)
CDK105090283(HACD2) 105095934(HACD4) 105100050(HACD1) 105100543(HACD3)
VPC102527236(HACD3) 102528377(HACD4) 102530852(HACD1) 102531667(HACD2)
BACU103007060(HACD4) 103007654(HACD2) 103010311(HACD3) 103016241(HACD1)
LVE103070282(HACD4) 103080072(HACD3) 103080415(HACD1) 103090885(HACD2)
OOR101280036 101282926(HACD2) 101283167(HACD3) 101284606(HACD1) 101287616(HACD4)
DLE111171655(HACD2) 111174707(HACD4) 111177733(HACD3) 111178111(HACD1)
PCAD102976395(HACD3) 102980866(HACD4) 102983044(HACD2) 102991229(HACD1)
PSIU116749464(HACD3) 116749857(HACD1) 116753047(HACD2) 116756071(HACD4)
ECB100053192(HACD3) 100064435(HACD4) 100068422(HACD1) 100070489(HACD2)
EPZ103541543(HACD3) 103547472(HACD2) 103563149(HACD4) 103563829 103564772(HACD1)
EAI106823720(HACD2) 106833939(HACD4) 106834423(HACD1) 106840593(HACD3)
MYB102239522(HACD2) 102243865(HACD1) 102250072(HACD4) 102260168(HACD3)
MYD102761248(HACD2) 102765145(HACD3) 102765511(HACD4) 102767778(HACD1)
MMYO118653989(HACD3) 118667582(HACD4) 118674274(HACD1) 118675394(HACD2)
MLF102416899(HACD4) 102417732(HACD1) 102424520(HACD3) 102424622(HACD2)
MNA107527243(HACD2) 107531444(HACD4) 107533796(HACD3) 107540621(HACD1)
PKL118716623(HACD4) 118719393(HACD3) 118724364(HACD2) 118730883(HACD1)
HAI109385238(HACD3) 109388107(HACD2) 109393552(HACD1) 109396414(HACD4)
DRO112302802(HACD4) 112311450(HACD3) 112318835(HACD1) 112320510(HACD2)
SHON118990735(HACD2) 118992325(HACD3) 118997144(HACD1) 118997998(HACD4)
AJM119039515(HACD2) 119045200(HACD1) 119055663(HACD4) 119057054(HACD3)
PDIC114490898(HACD2) 114493082(HACD3) 114493281(HACD1) 114503141(HACD4)
PHAS123808370(HACD3) 123819714(HACD4) 123827166(HACD2) 123831181(HACD1)
MMF118617375(HACD2) 118629574(HACD4) 118637851(HACD1) 118643233(HACD3)
RFQ117019229(HACD1) 117023515(HACD3) 117031491(HACD4) 117034318(HACD2)
PALE102878765(HACD3) 102881141(HACD4) 102890540(HACD2) 102896669(HACD1)
PGIG120586715(HACD2) 120604505(HACD3) 120607235(HACD4) 120614644(HACD1)
PVP105294224(HACD3) 105294912(HACD1) 105295610(HACD4) 105298141(HACD2)
RAY107508953(HACD3) 107513672(HACD1) 107518043(HACD2) 107518595(HACD4)
MJV108396724(HACD2) 108402530 108405522 108407866(HACD3) 108410057(HACD1)
TOD119231298(HACD4) 119238754(HACD3) 119244177(HACD1) 119257455(HACD2)
SARA101538040(HACD4) 101540254(HACD3) 101551553(HACD2) 101552703(HACD1)
LAV100663966(HACD4) 100666774(HACD3) 100673955(HACD1) 100677465(HACD2)
TMU101341391 101349356 101350820 101351753
DNM101411362(HACD4) 101437512(HACD3) 101441338(HACD1) 101443541(HACD2)
MDO100019614(HACD2) 100021176(HACD4) 100024526(HACD3)
GAS123231256(HACD4) 123236139(HACD3) 123240226 123242353(HACD2) 123249209(HACD1)
SHR100917310(HACD4) 100919102(HACD3) 100932461(HACD1)
PCW110194511(HACD1) 110199237(HACD4) 110206092(HACD3) 110208125(HACD2)
OAA100082970(HACD4) 100088741(HACD3) 100090771(HACD2) 100681153(HACD1)
GGA415539(HACD3) 420518(HACD1) 424251(HACD2) 427232(HACD4)
PCOC116225463(HACD3) 116227381(HACD2) 116239787(HACD4) 116243251(HACD1)
MGP100542802(HACD3) 100547269(HACD1) 100548753(HACD2) 104915048(HACD4)
CJO107306178(HACD4) 107309029(HACD1) 107316814(HACD2) 107318903(HACD3)
NMEL110390053(HACD4) 110394384(HACD1) 110400605(HACD2) 110404032(HACD3)
APLA101790464(HACD3) 101799288(HACD4) 101800675(HACD1) 101801258(HACD2)
ACYG106029896(HACD2) 106030350(HACD1) 106043672(HACD3) 106044147(HACD4)
AFUL116485776(HACD1) 116490532(HACD2) 116493330(HACD3) 116500760(HACD4)
TGU100222541(HACD3) 100223714(HACD2) 100225517(HACD4) 100226789(HACD1)
LSR110468291(HACD2) 110470689(HACD4) 110482430(HACD1) 110483016(HACD3)
SCAN103812789(HACD1) 103814311(HACD2) 103816239(HACD3) 103819442(HACD4)
PMOA120499126(HACD2) 120501492(HACD1) 120509219(HACD3) 120512075(HACD4)
OTC121333054(HACD4) 121337987(HACD1) 121337996(HACD2) 121343439(HACD3)
PRUF121354388(HACD3) 121356540(HACD2) 121363353(HACD4) 121364055(HACD1)
GFR102038446(HACD1) 102042345(HACD4) 102045004(HACD2) 102045414(HACD3)
FAB101806852(HACD4) 101810478(HACD2) 101817288(HACD3) 101817785(HACD1)
PHI102104879(HACD4) 102107099(HACD2) 102107704(HACD1) 102108630(HACD3)
PMAJ107200738(HACD1) 107207646(HACD2) 107209216(HACD3) 107216251(HACD4)
CCAE111924168(HACD1) 111932250(HACD2) 111933862(HACD3) 111940631(HACD4)
CCW104683887(HACD3) 104685211(HACD4) 104689351(HACD1) 109145688(HACD2)
ETL114055277(HACD3) 114056566(HACD4) 114058105(HACD2) 114066705(HACD1)
ZAB102061253(HACD1) 102068794(HACD3) 102071001(HACD2) 102073592(HACD4)
FPG101913688(HACD4) 101913832(HACD3) 101917611(HACD1) 101924533(HACD2)
FCH102051229(HACD1) 102052347(HACD2) 102057117(HACD3) 102058226(HACD4)
CLV102086789(HACD1) 102087259(HACD3) 102089080(HACD2) 102092183(HACD4)
EGZ104128106(PTPLB) 104128150(PTPLAD2) 104133674(PTPLAD1) 104135606(PTPLA)
NNI104013313(PTPLA) 104017928(PTPLAD2) 104020301(PTPLB)
PLET104614033(PTPLAD2) 104619313(PTPLAD1) 104620345(PTPLA) 104622919(PTPLB)
ACUN113476743(HACD1) 113481992(HACD2) 113483772(HACD3) 113490156(HACD4)
TALA104357427(HACD1) 104361033(HACD2) 104367460(HACD4) 104369130(HACD3)
PADL103914815(PTPLAD1) 103919637(PTPLB) 103920370(PTPLAD2) 103922410(PTPLA)
ACHC115336474(HACD4) 115339647(HACD1) 115341025(HACD3) 115342648(HACD2)
AAM106484416(HACD4) 106487656(HACD3) 106489953(HACD1) 106499043(HACD2)
AROW112969091(HACD1) 112969759(HACD3) 112969842(HACD4) 112973821(HACD2)
NPD112947343(HACD1) 112948261(HACD3) 112951313(HACD4) 112960128(HACD2)
DNE112981892(HACD4) 112982404(HACD1) 112994222(HACD2) 112996300(HACD3)
ASN102372217(HACD3) 102376647(HACD4) 102381766(HACD1) 102383472(HACD2)
AMJ102561980(HACD2) 102563025(HACD4) 102564740(HACD1) 102568329(HACD3)
CPOO109308184(HACD1) 109308788(HACD3) 109322647(HACD2) 109323363(HACD4)
GGN109288435(HACD3) 109291352(HACD1) 109301416(HACD2)
PSS102444601(HACD1) 102445253(HACD3) 102445343(HACD4) 102452110(HACD2)
CMY102932870(HACD1) 102935203(HACD2) 102940963(HACD4) 102942131(HACD3)
CPIC101944120(HACD4) 101948528(HACD1) 101950627(HACD2) 101952448(HACD3)
TST117872161(HACD1) 117879345(HACD4) 117883566(HACD3) 117884738(HACD2)
CABI116816644(HACD3) 116832870(HACD1) 116834735(HACD2) 116835085(HACD4)
MRV120373723(HACD3) 120374712(HACD2) 120397933(HACD1) 120408183(HACD4)
ACS100554600(hacd2) 100555369(hacd3) 100559315(hacd4) 100562288(hacd1)
PVT110077379(HACD4) 110083009(HACD2) 110085464(HACD3) 110085999(HACD1)
SUND121923150(HACD4) 121931162(HACD2) 121933191(HACD3) 121934969(HACD1)
PBI103049929(HACD3) 103057408(HACD4) 103061643(HACD2) 103067518(HACD1)
PMUR107283329(HACD1) 107288930(HACD2) 107290593(HACD3) 107293821(HACD4)
TSR106542103(HACD4) 106543610(HACD1) 106547910(HACD3) 106553088(HACD2)
PGUT117654919(HACD1) 117661539(HACD4) 117668895(HACD2) 117676159(HACD3)
VKO123020747(HACD1) 123022144(HACD4) 123027350(HACD2) 123030805(HACD3)
PMUA114583977(HACD3) 114588060(HACD4) 114603918(HACD2) 114607771(HACD1)
ZVI118091767(HACD2) 118091956(HACD1) 118092537(HACD3) 118097785(HACD4)
GJA107108159(HACD4) 107113909(HACD2) 107120973(HACD1) 107123789(HACD3)
STOW125424686(HACD3) 125427210(HACD2) 125436102(HACD4) 125441021(HACD1)
XLA108711496(hacd3.L) 108712807(hacd3.S) 108713839 108719872(hacd1.S) 446806(hacd2.S) 447050(hacd2.L) 494792(hacd1.L)
XTR100145048(hacd1) 100216187(hacd2) 100379797(hacd3) 100490902(hacd4)
NPR108784091(HACD3) 108793268(HACD1) 108794436(HACD4) 108803722(HACD2)
RTEM120931120(HACD3) 120939980(HACD1) 120944317(HACD2) 120945395(HACD4)
BBUF120986011(HACD3) 120989243(HACD4) 121001826(HACD1) 121008422(HACD2)
BGAR122923647(HACD2) 122927497(HACD3) 122938663(HACD1) 122943329(HACD4)
DRE334121(hacd2) 393441(hacd3) 553326(hacd1) 561303(hacd4)
SRX107714306 107730169(hacd1) 107731874 107738726 107741899 107742880
SANH107660639 107661144 107672296 107679243 107686290 107691470 107702201
SGH107555901 107558397 107568855 107571282 107580446 107583769 107596067(hacd2) 107596982
CCAR109052329 109064873 109076034 109076037 109093677 109095338 109097704
CAUA113052266 113053058 113061459 113069058 113074277(hacd1) 113108403 113118355
PPRM120461586(hacd2) 120465335(hacd4) 120465336 120480173(hacd1) 120493841(hacd3)
MAMB125254196(hacd3) 125265475(hacd4) 125265862(hacd1) 125270202(hacd2)
IPU108264727 108266254(hacd2) 108267784(hacd4) 108268178(hacd1) 108270680 124626851
PHYP113523935 113525983(hacd2) 113534457(hacd3) 113540181(hacd4) 113540213(hacd1)
SMEO124380173(hacd2) 124387430(hacd1) 124388137(hacd4) 124391044 124395560(hacd3)
TFD113646179 113652515(hacd3) 113654298(hacd2) 113657410(hacd4) 113657502(hacd1)
AMEX103025300(hacd1) 103030275(hacd4) 103030449(hacd2) 103030450(hacd3) 103034430
EEE113567483(hacd2) 113569789 113581815(hacd4) 113588583(hacd3) 113591647(hacd1)
TRU101065304 101067691(hacd4) 101070268(hacd2) 101071733 101071736(hacd1)
TNGGSTEN00016014G001
LCO104918229(hacd2) 104922314(hacd3) 104927197(hacd4) 104929560(hacd1) 104929620
NCC104949190 104950795(ptpla) 104966220(ptplad2) 104966911(ptplad1)
CGOB115006368 115009552(hacd3) 115023460(hacd4) 115025516(hacd1) 115026596(hacd2)
ELY117246049(hacd4) 117251579(hacd2) 117258695 117262276 117262287 117264892(hacd1)
PLEP121946343 121949013(hacd2) 121949811(hacd3) 121961017(hacd1) 121961988(hacd4)
SLUC116038735(hacd3) 116045309(hacd1) 116049816(hacd4) 116066942(hacd2) 116067208
ECRA117934571(hacd4) 117937886(hacd1) 117940705 117948420(hacd3) 117952807(hacd2)
PFLV114545480(hacd4) 114549653(hacd1) 114552624 114559570 114563807(hacd2)
GAT120809165(hacd3) 120811006 120811603(hacd1) 120821491(hacd4) 120833975(hacd2)
PPUG119196178(hacd3) 119198825(hacd1) 119222448(hacd4) 119224913 119229127(hacd2)
MSAM119884173 119890603 119893183(hacd3) 119904438(hacd2) 119911125(hacd1) 119912063(hacd4)
CUD121504566(hacd4) 121512546 121515619(hacd3) 121522168(hacd2) 121527157(hacd1)
ALAT119008363(hacd1) 119018787 119025170(hacd3) 119025476(hacd2) 119027314(hacd4)
MZE101467683 101468089 101472136 101479872(hacd1) 101481030(hacd2) 112430987
ONL100693501(hacd3) 100698433(hacd2) 100702753 100709129(hacd1) 100712248(hacd4)
OAU116309248(hacd4) 116314773(hacd2) 116321190 116326165(hacd3) 116329254(hacd1)
OLA101155409 101162008(hacd1) 101163569(hacd3) 101172608(hacd4) 101174470(hacd2)
OML112151174(hacd1) 112152159(hacd3) 112155307(hacd2) 112155875(hacd4) 112160247
XMA102221140 102222666(hacd4) 102227054(hacd2) 102229999(hacd1) 102234597(hacd3)
XCO114136771(hacd1) 114143381 114147919(hacd2) 114157528(hacd4) 114159466(hacd3)
XHE116711716(hacd1) 116719063 116722847(hacd2) 116732786(hacd4) 116734006(hacd3)
PRET103456872(hacd1) 103462920 103466552(hacd3) 103478473(hacd2) 103480097(hacd4)
PFOR103131725 103132680 103134830 103140483(hacd1) 103141261(hacd3) 103142639
PLAI106934815(hacd2) 106940002 106940228 106953204 106959493 106962037(hacd1)
PMEI106904082 106915375(hacd1) 106924060 106925849 106927160
GAF122820410(hacd4) 122824534(hacd1) 122835033(hacd3) 122840443(hacd2) 122845396
CVG107083857 107086488(hacd1) 107092065(hacd2) 107101687(hacd3) 107102688(hacd4)
CTUL119772222(hacd2) 119772409(hacd3) 119773658 119791670(hacd1) 119792638(hacd4)
GMU124858487(hacd1) 124866441 124871486(hacd2) 124880450(hacd4) 124883187(hacd3)
NFU107381835 107382509(hacd1) 107384754(hacd4) 107388728(hacd3) 107389654(hacd2)
KMR108229839(hacd3) 108230429(hacd1) 108238871(hacd2) 108242096 108242276(hacd4)
ALIM106514402 106520970(hacd1) 106524716 106526456(hacd4) 106534812(hacd2)
NWH119414505(hacd4) 119415766(hacd3) 119419478(hacd2) 119426765(hacd1) 119430265
AOCE111564268(hacd4) 111573706(hacd2) 111575115 111575705 111584876(hacd1)
CSEM103377442(hacd1) 103385367(hacd4) 103391652(hacd2) 103398371(hacd3)
POV109624511(hacd3) 109629732(hacd1) 109637297 109637658(hacd4) 109637959(hacd2)
SSEN122765320(hacd2) 122766861(hacd4) 122772320 122775646(hacd3) 122781287(hacd1)
HHIP117752111 117753897(hacd1) 117755032(hacd2) 117763819(hacd3) 117779196(hacd4)
HSP118098316(hacd1) 118102228(hacd4) 118109325(hacd3) 118115037 118119819(hacd2)
LCF108877170 108886346 108887771 108894997(hacd1) 108895191(hacd4) 108897096 108897097(hacd2)
SDU111218454(hacd2) 111223573(hacd4) 111223732 111228459 111237858(hacd1)
SLAL111655050 111657539(hacd2) 111665138(hacd1) 111666949 111667967(hacd4)
XGL120790044(hacd1) 120791224 120793133(hacd3) 120797219(hacd4) 120801766(hacd2)
HCQ109508471 109514439 109519408(hacd3) 109521945(hacd2) 109529828(hacd1)
BPEC110156632(hacd2) 110163817 110170077(hacd1) 110170715(hacd4) 110172190
MALB109951754(hacd1) 109957257(hacd4) 109971234(hacd3) 109974036(hacd2) 109974792
BSPL114845305(hacd4) 114846820(hacd2) 114852199 114853651(hacd1) 114856790(hacd3)
SASA100196500(phs1) 100286513(hacd3) 106562668 106577593(hacd4) 106578705 106582347(hacd2) 106587973 106590135
OTW112215652 112225594(hacd2) 112227975 112237672 112237936(hacd3) 112238538 112260000(hacd4)
OMY110489947 110501810(hacd2) 110506999 110520266 110521149(hacd3) 110531773(hacd4) 110535618 118964981
OGO123991085 124007829(hacd4) 124019745 124019746 124037434 124039792 124043988 124047869
ONE115105162 115110758 115130125 115130382(hacd1) 115138119(hacd4)
SALP111953574(hacd1) 111959456 111960455(hacd4) 111977141 111977268
SNH120028088 120030382(hacd4) 120037726 120048369 120051155 120058332 120064254(hacd2)
ELS105007668 105016954(hacd2) 105019343(hacd1) 105026498 105029497(hacd4)
SFM108928894 108936301 108937043(hacd1) 108938766(hacd4) 108941236(hacd3)
PKI111834292(hacd1) 111847353(hacd3) 111848712(hacd4) 111851746(hacd2)
AANG118214157 118215369(hacd3) 118223734(hacd2) 118224813(hacd1) 118231186(hacd4)
LOC102690616(hacd1) 102690689(hacd2) 102690929(hacd3) 102691334(hacd4)
PSPA121294953 121296264(hacd4) 121298566 121312696 121314150 121321485 121322601
ARUT117394187 117399327 117403104 117408626(hacd4) 117426464 117427772 117429184
LCM102350254 102357175(HACD1) 102361655(HACD3) 102362801(HACD4)
CMK103171834(hacd2) 103181578(hacd1) 103182850(hacd4) 103186443(hacd3)
RTP109911757 109915845(hacd3) 109917061(hacd2) 109930012(hacd1)
BFO118405161 118410363 118417843
BBEL109469406 109471876 109473478
CIN100175762 100184399
SCLV120329207 120341962
SPU592170 592581
APLC110979520 110987860
SKO100370601 100376136
DMEDmel_CG6746(Hacd1) Dmel_CG9267(Hacd2)
DER6542114 6543322
DSE6617692 6617873
DSIDsimw501_GD22057(Dsim_GD22057) Dsimw501_GD22144(Dsim_GD22144)
DYADyak_GE11580 Dyak_GE12555
DAN6498308 6504311
DSR110184945 110185080
DPODpse_GA19829 Dpse_GA21658
DPE6593824 6595437
DMN108162726 108163439
DWI6641577 6641845
DGR6562491 6566942
DMODmoj_GI17184 Dmoj_GI18216
DAZ108610209 108611759
DNV115562361 115563940
DHE111594788 111595409
DVI6628927 6634143
CCAT101452332 101456497
BOD106623405 106627658
MDE101900017 101900652
SCAC106084885 106092949
LCQ111679652 111681078
LSQ119603986 119608822
HIS119658717 119660987
AGAAgaP_AGAP003814 AgaP_AGAP003815
ACOZ120949211 120949213
AARA120894731 120894734
ASTE118502603 118502604
AAG5566155 5566159
AALB109415338 109415340 109423651
CQUCpipJ_CPIJ011113 CpipJ_CPIJ011114
CPII120419716 120419718 120424007 120424008
CNS116342436 116344453
BCOO119074643 119076485
AME100577192 413078
ACER107993088 107997390
ALAB122711965 122714580
BIM100744206 100744962
BBIF117205208 117208870
BVK117230285 117230396
BVAN117160514 117161596
BTER100642777 100645881
BPYO122572139 122575989
CCAL108630662 108632109
OBB114873054 114880368
MGEN117220578 117223346
NMEA116431214 116433661
CGIG122403693 122404319
SOC105197427 105200204
MPHA105830349 105834438
AEC105148293 105153349
ACEP105621482 105624468
PBAR105425289 105429232
VEM105561184 105564302
HST105183312 105188575
DQU106750335 106751032
CFO105251955 105255797
FEX115242088 115242970
LHU105671527 105671856
PGC109853799 109855778
OBO105278848 105282861
PCF106791659 106793815
PFUC122518981 122519407
VPS122631637 122634508
NVI100115280 100119292
CSOL105368253
TPRE106648553
MDL103577177 103577877
CGLO123258576 123261136
FAS105272374 105273018
DAM107037834 107039262
AGIF122847549 122847550 122859603
CCIN107263280 107270713
TCA656186 657574
DPA109534755
SOY115879443 115889474
ATD109598470 109598524
CSET123310827 123316105
AGB108910983 108916395
LDC111509080 111512170
NVL108561128 108563860
APLN108735665 108735770
PPYR116162971 116170379
OTU111413754 111424939
BMOR101746115 732939
BMAN114239773 114249382
MSEX115440876 115445744
DPLKGM_205389 KGM_216086
BANY112043306 112049507
PMAC106710023 106712344
PPOT106104854 106108164
PXU106115539 106117495 106119391
PRAP111002301 111003202
ZCE119830588 119839683
HAW110369837 110384237
TNL113492670 113492676 113493843
SLIU111353814 111355089
OFU114350964 114354320 114354624
PXY105382787 105388332 105394763
API100144797
DNX107169083
AGS114121523
RMD113561338
BTAB109032301
DCI103505728 103505730
CLEC106663747 106667710
HHAL106678049 106686090
NLU111055939 111060208
PHUPhum_PHUM075720 Phum_PHUM307650
FOC113201719 113216772
TPAL117640111 117644320
ZNE110832233 110832923
CSEC111863850 111867840
FCD110851849 110852950
DPXDAPPUDRAFT_219048 DAPPUDRAFT_305850
DMK116931931 116936297
PVM113800269 113819729
PJA122253633 122258704
PCHN125039613 125043606
HAME121861518 121871436
PCLA123750506 123754047
PTRU123504654 123504731
HAZT108671106 108681462
EAF111705648 111707972
LSM121119670 121119671 121121798
PPOI119096086 119099695 119103137 119103893
ISCIscW_ISCW018099 IscW_ISCW021603
DSV119433578 119442659
RSAN119387306 119387433 119404666
RMP119188288
VDE111244902 111248104
VJA111267677 111267956
TUT107364580 107368141 107368497
DPTE113789180 113797446
DFR124493470 124494750
CSCU111624268 111625510
PTEP107439802 107452655
SDM118183796 118201577 118204237
CELCELE_T15B7.2(hpo-8)
CBRCBG_19031(Cbr-hpo-8)
BMYBM_BM16897(Bm16897) BM_BM5803(Bma-hpo-8)
LOALOAG_01917 LOAG_03759
NAINECAME_00058
HROHELRODRAFT_103959 HELRODRAFT_67129
LGILOTGIDRAFT_120462 LOTGIDRAFT_222938
PCAN112554354 112562355
BGT106067823 106068648
GAE121377076 121378683 121389125
HRF124135705 124139439
HRJ124255820 124270010
CRG105344957 105346790
MYI110445680 110458019
PMAX117316845 117334698
MMER123522861 123540417
OBI106881918 106882568
OSN115210895 115217987
LAK106158390 106167794
SMMSmp_022700.1 Smp_121880
SHXMS3_0013859
OVIT265_07006 T265_14247
EGLEGR_04347 EGR_05080
NVE5501386 5503430
EPA110234341 110245952
ATEN116300097 116302559
ADF107346286 107348530
AMIL114957812 114975404
PDAM113672916 113675156
SPIS111324704 111341830
DGT114522643 114525148
XEN124433562 124457886
HMG100205849 101237619
TADTRIADDRAFT_54534 TRIADDRAFT_64088
AQU100631401 100641930 105313298
ATHAT5G10480(PAS2) AT5G59770
ALY9302421 9309529
CRB17876617 17881691
CSAT104708051 104726571 104735060 104737093 104763584 104769253
EUSEUTSA_v10014612mg EUTSA_v10014620mg EUTSA_v10027965mg
BRP103846802 103851552 103855870
BNA106372468 106384895 106385553 106386856 106405914 106430302 106441127
BOE106315704 106325112 106331496
RSZ108817701 108829467 108844366
THJ104798725 104810801 104819292
CPAP110806954 110814385 110814409
CIT102610324 102621321
CICCICLE_v10029246mg
PVY116105263 116111289 116119283 116146392
MINC123199662 123211573 123225139
TCC18590754 18611467
GRA105788887 105804148
GHI107913394 107950284 107963934 121202797
GAB108461202 108484236
DZI111299885 111304317 111316144
EGR104426317 104432769
GMX100527150 100527607 100818356
GSJ114370453 114376730 114394875 114423087
PVUPHAVU_002G147400g PHAVU_003G289100g PHAVU_011G067100g
VRA106755143 106755607 106776467 106779219
VAR108319827 108323452 108332862
VUN114168881 114171090 114176749
CCAJ109798479 109801425 109818376
APRC113858516 113858824
MTRMTR_4g060990 MTR_8g471160
CAM101495386 101495713 101507943
LJALj0g3v0016519.1(Lj0g3v0016519.1) Lj0g3v0339429.1(Lj0g3v0339429.1) Lj0g3v0339429.2(Lj0g3v0339429.2) Lj3g3v3155120.1(Lj3g3v3155120.1)
ADU107476878 107487258
AIP107629135 107633062 107640978 107642273
AHF112733908 112736599 112747327 112750702 112787034 112799944
LANG109349147 109355362 109363351
FVE101300284 101304749
RCN112190403 112202859
PPER18772196 18773179
PMUM103322718 103334912
PAVI110762100 110768564
PDUL117630823 117631169
MDM103413128 103421525
PXB103948952 103954176
ZJU107425132 107425142
MNT21391901 21394128
CSV101212013 101214048
CMO103490580 103493277
BHJ120087868 120090036
MCHA111008101 111017094
CMAX111474885 111489300 111499642
CMOS111447328 111447818 111451609
CPEP111794491
RCU8277640 8286117
JCU105628210 105641681
HBR110651448 110660241
MESC110611705 110626940 110630510
POP7480190 7485725
PEU105107909 105123808
PALZ118045675 118063184
JRE108980321 109005346 109021972
QSU111993776 111994437 112018088 112021402
QLO115950727 115987884
TWL119995324 120001439 120013530
VVI100255240 100261741
VRI117916636 117919063
SLY101245050 101246492 101262991
SPEN107004641 107018380
SOT102586361 102591777
CANN107851522 107856569 107870144
NTA107761121 107779652 107791219 107803408 107809738 107826616
NSY104220147 104220473 104244293 104246059
NTO104087329 104114910 104121448
NAU109239572 109240388 109240786
INI109180148 109188898 109192762
ITR116013695 116017021
SIND105169658 105170380 105176449
OEU111388239 111393815 111410069
EGT105949163 105957372
SSPL121740919 121745703 121746653 121750470
HAN110865262 110891046 110909130
ECAD122591068 122603646 122610786
LSV111883443 111909462 111919009
CCAV112505755 112528404
DCR108216565 108217631 108222238
CSIN114267780 114278065
BVG104895506 104900172
SOE110797744 110803996
CQI110682075 110684120 110688483 110695243
NNU104594622 104595487 104611912
MING122075130 122075436
TSS122649485 122662546
PSOM113283320 113286213 113308766 113321049 113356513 113356515 113356516 113359620
NCOL116249819 116255723
OSA107277374 4324520 4324521 4324522 4335343 4339019 9272625
DOSAOs01t0150200-01(Os01g0150200) Os01t0150400-00(Os01g0150400) Os01t0150500-00(Os01g0150500) Os01t0150800-01(Os01g0150800) Os04t0271200-01(Os04g0271200) Os05t0460800-01(Os05g0460800) Os08t0393600-01(Os08g0393600)
OBR102714459 102717559 102717835
BDI100821089 100840117 100842646 106866263
ATS109749525 109749710 109757348 109766983
TDC119266979 119270784 119271155 119274775 119274778 119278998 119280820 119282510 119316030 119325556 119347549
TAES123057821 123059144 123060151 123063715 123064819 123064820 123068635 123073970 123073971 123077160 123081023 123093167 123093603 123131106 123134720 123136094 123160637 123172491 123172493 123175950 123176438 123182270
TUA125520823 125527398 125528804 125530533 125542660 125546370
SBI8060797 8060798 8061772
ZMA100274548 100284318 100383128
SITA101782661 101783244
SVS117848393 117855552
PVIR120641618 120665239 120676869 120705978
PHAI112885929 112893032 112894083
PDA103703452 103705939
EGU105044431 105045727
MUS103968992 103975400 103991715
DCT110114829 110115839
PEQ110028079
AOF109829903 109847558 109850026
ATR18434145 18442669
SMOSELMODRAFT_122503(PAS2-1) SELMODRAFT_125223(PAS2-2) SELMODRAFT_451040
PPP112289823 112295075
CRECHLRE_08g363500v5
VCNVOLCADRAFT_61480 VOLCADRAFT_83422
MNGMNEG_12140 MNEG_9418
CSLCOCSUDRAFT_14404 COCSUDRAFT_83443
CVRCHLNCDRAFT_137564 CHLNCDRAFT_143333
APROF751_6284
OLUOSTLU_13214 OSTLU_29682 OSTLU_87349
OTAOT_ostta05g03730 OT_ostta13g02530
BPGBathy03g04510 Bathy04g02110
MISMICPUN_58684 MICPUN_59337
MPPMICPUCDRAFT_44656 MICPUCDRAFT_58952
CMECYME_CMR006C
GSLGasu_12280
CCPCHC_T00005797001 CHC_T00008580001
SCEYJL097W(PHS1)
SEUBDI49_2923
SPAOSPAR_J01090
AGOAGOS_AFR090W
ERCEcym_6346
KLAKLLA0_F14146g
KMXKLMA_30158(PHS1)
LTHKLTH0D03410g
VPOKpol_1016p17
ZROZYRO0G15334g
CGRCAGL0L03564g
NCSNCAS_0A09490(NCAS0A09490)
NDINDAI_0G05450(NDAI0G05450)
TPFTPHA_0B01300(TPHA0B01300)
TBLTBLA_0C02950(TBLA0C02950)
TDLTDEL_0D01380(TDEL0D01380)
TGBHG536_0F01520
KAFKAFR_0A01400(KAFR0A01400)
KNGKNAG_0B01760(KNAG0B01760)
ZMKHG535_0H01030
PPAPAS_chr3_0222
DHADEHA2C17424g DEHA2C17446g
PICPICST_56836 PICST_57597
PGUPGUG_03908 PGUG_03909
SPAASPAPADRAFT_63465
LELLELG_05220 LELG_05221
CALCAALFM_C703040WA(CaO19.5157) CAALFM_C703050WA(CaO19.5156)
CTPCTRG_05223 CTRG_05224
COTCORT_0G04450 CORT_0G04460
CDUCD36_72700 CD36_72710
CTENCANTEDRAFT_113290 CANTEDRAFT_120092
YLIYALI0F11935g
CLUCLUG_00450
CLUSA9F13_08g02574
CAURCJI97_004909 CJI97_004910
PKZC5L36_0C02520
BNNFOA43_004210
BBRXBRETT_001992
OPAHPODL_02239
SLUDSCDLUD_003669
NCRNCU08985
NTENEUTE1DRAFT82561(NEUTE1DRAFT_82561)
SMPSMAC_01940
PANPODANSg5141
TTTTHITE_2023698
MTMMYCTH_2304523
CTHRCTHT_0027140
MGRMGG_04972 MGG_07602
PPEIPpBr36_02581 PpBr36_03345
TMNUCRPA7_2257
SSCKSPSK_09777
FGRFGSG_07304 FGSG_12648
FPUFPSE_01073 FPSE_04001
FVRFVEG_03595 FVEG_05273
FOXFOXG_02109 FOXG_05748
NHENECHADRAFT_38495 NECHADRAFT_82566
TRETRIREDRAFT_105055
TRRM419DRAFT_6017
MAWMAC_00591
MAJMAA_05922
CMTCCM_01449
PLJVFPFJ_05612
VALVDBG_02620 VDBG_04601
VDAVDAG_04151 VDAG_09815
CFJCFIO01_04331 CFIO01_04885
CHIGCH63R_00275 CH63R_03084
SAPOSAPIO_CDS5771
ELAUCREL1_11623
PFYPFICI_02491 PFICI_11745
SSLSS1G_03177
BFUBCIN_08g03790(Bcphs1)
MBEMBM_07029 MBM_07077
PSCOLY89DRAFT_681296
GLZGLAREA_04533
ANIAN5000.2
AFMAFUA_4G10270
ACTACLA_049480
NFINFIA_067410 NFIA_105790
AORAO090003001195 AO090005001257
ANGANI_1_1650144(An16g03550) ANI_1_1990184(An04g06650)
AFVAFLA_000113 AFLA_000473
ALUCAKAW2_30331A AKAW2_70304A
ACHEACHE_10748A ACHE_20933S
APUUAPUU_21043A APUU_30827A
PCSPc22g12490
PDPPDIP_25110
TMFPMAA_096650
TRGTRUGW13939_11377
CIMCIMG_09068
CPWCPC735_015040
UREUREG_03318
PBLPAAG_08221
PBNPADG_01997
AJEHCAG_01309
BGHBDBG_06179
PNOSNOG_12970 SNOG_15979
PTEPTT_07276 PTT_15392
BZECOCCADRAFT_109010 COCCADRAFT_34753
BSCCOCSADRAFT_159899 COCSADRAFT_91005
BORCOCMIDRAFT_34556 COCMIDRAFT_97448
AALTCC77DRAFT_23611 CC77DRAFT_951058
ZTRMYCGRDRAFT_87635
PFJMYCFIDRAFT_45204
BCOMBAUCODRAFT_32422
NPAUCRNP2_4724
TMLGSTUM_00009842001
SPOSPBC19C2.15c
CNECNE00730
CNBCNBE0670
CNGCNAG_02487
CGICGB_E0700C
TMSTREMEDRAFT_25191
PPLPOSPLDRAFT_104986
TVSTRAVEDRAFT_56436
DSQDICSQDRAFT_133109
PCOPHACADRAFT_258569
SHSSTEHIDRAFT_141441
HIRHETIRDRAFT_476130
PSQPUNSTDRAFT_42833
ADLAURDEDRAFT_111144
FMEFOMMEDRAFT_107800
GTRGLOTRDRAFT_58018
MRRMoror_14683 Moror_6971
MOREE1B28_003460 E1B28_003475
CCICC1G_11544
SCMSCHCODRAFT_77419
ABPAGABI1DRAFT71504(AGABI1DRAFT_71504)
ABVAGABI2DRAFT192575(AGABI2DRAFT_192575)
CPUTCONPUDRAFT_101959
SLASERLADRAFT_466079
WSEWALSEDRAFT_59139
UMAUMAG_00007
PFPPFL1_00095
MGLMGL_2260
MRTMRET_0252
MSYMMSY001_1981
MLRMELLADRAFT_38757
ECUECU05_1430
EINEint_051490
EHEEHEL_051560
EROEROM_051500
NCENCER_101417
SREPTSG_07138
DDIDDB_G0278113 DDB_G0278683
DPPDICPUDRAFT_151830 DICPUDRAFT_89327
DFADFA_06437 DFA_07051
EHIEHI_110570(58.t00004)
EDIEDI_053980
EIVEIN_047440
ACANACA1_073320 ACA1_186090 ACA1_186210 ACA1_309340
PFAPF3D7_1331600
PFDPFDG_02031
PFHPFHG_02827
PREIPRSY57_0019600
PYOPY17X_1351400
PCBPCHAS_135110(PC301025.00.0)
PBEPBANKA_1346500
PVVPVVCY_1304920
PKNPKNH_1268900
PVXPVX_082515
PCYPCYB_123100
BEQBEWA_020340
BBIGBBBOND_0307750
CPVcgd3_2150
CHOChro.30252
TGOTGME49_311290
TETTTHERM_00538900
PTMGSPATT00009568001
AAFAURANDRAFT_29797
PIFPITG_14831
PSOJPHYSODRAFT_433551
SPARSPRG_10884
GTTGUITHDRAFT_105298
TBRTb10.406.0290
TBGTbgDal_X12870
TCR511635.40
LMALMJF_05_0280
LIFLINJ_05_0280
LDOLDBPK_050280
LMILMXM_05_0280
LBZLBRM_05_0270
LPANLPMP_050270
NGRNAEGRDRAFT_33547 NAEGRDRAFT_35609
GLAGL50803_007512
MADHP15_2720
MARIACP86_20830
 » show all
Reference
1  [PMID:18799749]
  Authors
Bach L, Michaelson LV, Haslam R, Bellec Y, Gissot L, Marion J, Da Costa M, Boutin JP, Miquel M, Tellier F, Domergue F, Markham JE, Beaudoin F, Napier JA, Faure JD
  Title
The very-long-chain hydroxy fatty acyl-CoA dehydratase PASTICCINO2 is essential and limiting for plant development.
  Journal
Proc Natl Acad Sci U S A 105:14727-31 (2008)
DOI:10.1073/pnas.0805089105
  Sequence
[ath:AT5G10480]
Reference
2  [PMID:18272525]
  Authors
Kihara A, Sakuraba H, Ikeda M, Denpoh A, Igarashi Y
  Title
Membrane topology and essential amino acid residues of Phs1, a 3-hydroxyacyl-CoA  dehydratase involved in very long-chain fatty acid elongation.
  Journal
J Biol Chem 283:11199-209 (2008)
DOI:10.1074/jbc.M708993200
  Sequence
[sce:YJL097W]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.134
IUBMB Enzyme Nomenclature: 4.2.1.134
ExPASy - ENZYME nomenclature database: 4.2.1.134
BRENDA, the Enzyme Database: 4.2.1.134
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