KEGG   ENZYME: 4.2.1.146
Entry
EC 4.2.1.146                Enzyme                                 
Name
L-galactonate dehydratase;
LGD1
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
L-galactonate hydro-lyase (2-dehydro-3-deoxy-L-galactonate-forming)
Reaction(IUBMB)
L-galactonate = 2-dehydro-3-deoxy-L-galactonate + H2O [RN:R10532]
Reaction(KEGG)
R10532
Substrate
L-galactonate [CPD:C15930]
Product
2-dehydro-3-deoxy-L-galactonate [CPD:C20680];
H2O [CPD:C00001]
Comment
The enzyme takes part in a D-galacturonate degradation pathway in the fungi Trichoderma reesei (Hypocrea jecorina) and Aspergillus niger.
History
EC 4.2.1.146 created 2013
Pathway
ec00040  Pentose and glucuronate interconversions
ec01100  Metabolic pathways
Orthology
K18102  L-galactonate dehydratase
Genes
QSU111983292 111987843
PPAPAS_chr4_0572
PGUPGUG_05189
CTENCANTEDRAFT_135663
SLBAWJ20_3253 AWJ20_3295
NCRNCU07064
NTENEUTE1DRAFT131658(NEUTE1DRAFT_131658)
SMPSMAC_03881
PANPODANSg3017
TTTTHITE_2153466
MTMMYCTH_2064932 MYCTH_82505
CTHRCTHT_0042160
MGRMGG_01300
PPEIPpBr36_00810
TMNUCRPA7_2751 UCRPA7_4700
SSCKSPSK_00800 SPSK_03340 SPSK_06299
FGRFGSG_09257
FPUFPSE_09649
FVRFVEG_03852 FVEG_12512 FVEG_12549
FOXFOXG_05984 FOXG_15221 FOXG_17432
NHENECHADRAFT_56323 NECHADRAFT_66837
TRETRIREDRAFT_104599 TRIREDRAFT_66662
TRRM419DRAFT_11053 M419DRAFT_73300
MAWMAC_03404
MAJMAA_02004
CMTCCM_00320
PLJVFPFJ_04113 VFPFJ_07689
VALVDBG_08188
VDAVDAG_10081
CFJCFIO01_10120
CHIGCH63R_14134
SAPOSAPIO_CDS5438 SAPIO_CDS6402
ELAUCREL1_8211
PFYPFICI_14149
SSLSS1G_12905
BFUBCIN_01g09450(Bclgd1)
MBEMBM_09691
PSCOLY89DRAFT_610683
GLZGLAREA_00035
ANIAN6035.2
AFMAFUA_2G09810
ACTACLA_068890
NFINFIA_085260
AORAO090011000654
ANGANI_1_1784144(An16g05390)
AFVAFLA_008058
ALUCAKAW2_70451A(LGD1)
ACHEACHE_40955S(LGD1)
APUUAPUU_11124A(LGD1)
PCSPc16g00120 Pc22g19710
PDPPDIP_64950
TMFPMAA_087210
TRGTRUGW13939_01876 TRUGW13939_04485
ABEARB_05174
TVETRV_03587
PNOSNOG_13604
PTEPTT_15544
BZECOCCADRAFT_3106
BSCCOCSADRAFT_180831
BORCOCMIDRAFT_2503
AALTCC77DRAFT_1017550
ZTRMYCGRDRAFT_71623
PFJMYCFIDRAFT_37783
FFUCLAFUR5_08447
BCOMBAUCODRAFT_37158
NPAUCRNP2_9857
TMLGSTUM_00012245001
TMSTREMEDRAFT_30567 TREMEDRAFT_58672
TASAA1Q1_01111
 » show all
Reference
1  [PMID:16879654]
  Authors
Kuorelahti S, Jouhten P, Maaheimo H, Penttila M, Richard P
  Title
L-galactonate dehydratase is part of the fungal path for D-galacturonic acid catabolism.
  Journal
Mol Microbiol 61:1060-8 (2006)
DOI:10.1111/j.1365-2958.2006.05294.x
  Sequence
Reference
2  [PMID:18768163]
  Authors
Martens-Uzunova ES, Schaap PJ
  Title
An evolutionary conserved d-galacturonic acid metabolic pathway operates across filamentous fungi capable of pectin degradation.
  Journal
Fungal Genet Biol 45:1449-57 (2008)
DOI:10.1016/j.fgb.2008.08.002
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.146
IUBMB Enzyme Nomenclature: 4.2.1.146
ExPASy - ENZYME nomenclature database: 4.2.1.146
BRENDA, the Enzyme Database: 4.2.1.146
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