| Entry |
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| Name |
L-lyxonate dehydratase;
lyxD (gene name)
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| Class |
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
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| Sysname |
L-lyxonate hydro-lyase
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| Reaction(IUBMB) |
L-lyxonate = 2-dehydro-3-deoxy-L-arabinonate + H2O [RN: R12761]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
2-dehydro-3-deoxy-L-arabinonate [CPD: C00684];
H2O [CPD: C00001]
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| Comment |
The enzyme, characterized from several bacterial species, is involved in an L-lyxonate degradation pathway.
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| History |
EC 4.2.1.176 created 2021
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| Pathway |
| ec00053 | Ascorbate and aldarate metabolism |
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| Orthology |
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| Genes |
| PPRC: | PFLCHA0_c15650(rhmD) |
| HCK: | MRB56_00230 MRB56_05650 |
| REH: | H16_B0217(h16_B0217) |
| PAZZ: | PBP221_15990 PBP221_86540 |
| PLG: | NCTC10937_00902(rhmD) |
| AXX: | ERS451415_04606(rhmD) |
| SINL: | DSM14862_02692(rhmD) |
| SPAG: | sphantq_04351(rhmD_2) |
| SSPE: | ACGY09_06860 ACGY09_25495 |
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| Reference |
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| Authors |
Ghasempur S, Eswaramoorthy S, Hillerich BS, Seidel RD, Swaminathan S, Almo SC, Gerlt JA. |
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| Title |
Discovery of a novel L-lyxonate degradation pathway in Pseudomonas aeruginosa PAO1. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 4.2.1.176 |
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| LinkDB |
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