KEGG   ENZYME: 4.2.1.32
Entry
EC 4.2.1.32                 Enzyme                                 
Name
L(+)-tartrate dehydratase;
tartrate dehydratase;
tartaric acid dehydrase;
L-tartrate dehydratase;
L-(+)-tartaric acid dehydratase;
(R,R)-tartrate hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
(R,R)-tartrate hydro-lyase (oxaloacetate-forming)
Reaction(IUBMB)
(R,R)-tartrate = oxaloacetate + H2O [RN:R00339]
Reaction(KEGG)
R00339
Substrate
(R,R)-tartrate [CPD:C00898]
Product
oxaloacetate [CPD:C00036];
H2O [CPD:C00001]
Comment
The enzyme exists in an inactive low-molecular-mass form, which is converted into active enzyme in the presence of Fe2+ and thiol. cf. EC 4.2.1.81 D(-)-tartrate dehydratase.
History
EC 4.2.1.32 created 1972, modified 1986
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
ec01100  Metabolic pathways
Orthology
K03779  L(+)-tartrate dehydratase alpha subunit
K03780  L(+)-tartrate dehydratase beta subunit
Genes
ECOb3061(ttdA) b3062(ttdB)
ECJJW3033(ttdA) JW3034(ttdB)
ECDECDH10B_3236(ttdA) ECDH10B_3237(ttdB)
EBWBWG_2772(ttdA) BWG_2773(ttdB)
ECOKECMDS42_2530(ttdA) ECMDS42_2531(ttdB)
ECEZ4414(ttdA) Z4415(ttdB)
ECSECs_3944(ttdA) ECs_3945(ttdB)
ECFECH74115_4373(ddtA) ECH74115_4374(ttdB)
ETWECSP_4034(ttdA) ECSP_4035(ttdB)
ELXCDCO157_3685 CDCO157_3686
EOIECO111_3884(ttdA) ECO111_3885(ttdB)
EOJECO26_4163(ttdA) ECO26_4164(ttdB)
EOHECO103_3741(ttdA) ECO103_3742(ttdB)
ECOOECRM13514_3955(ttdA) ECRM13514_3956(ttdB)
ECOHECRM13516_3823(ttdA) ECRM13516_3824(ttdB)
ESLO3K_03640 O3K_03645
ESOO3O_22000 O3O_22005
ESMO3M_03680 O3M_03685
ECKEC55989_3476(ttdA) EC55989_3477(ttdB)
ECGE2348C_3354(ttdA) E2348C_3355(ttdB)
EOKG2583_3785(ttdA) G2583_3786(ttdB)
ELRECO55CA74_18035 ECO55CA74_18040
ELHETEC_3332 ETEC_3333
ECWEcE24377A_3525(ddtA) EcE24377A_3526(ttdB)
EUNUMNK88_3813 UMNK88_3814
ECPECP_3151 ECP_3152
ENAECNA114_3153(ttdA) ECNA114_3154(ttdB)
ECOSEC958_3467(ttdA) EC958_3468(ttdB)
ECVAPECO1_3352(ttdB) APECO1_3353(ttdA)
ECOAAPECO78_19115 APECO78_19120
ECXEcHS_A3241(ddtA) EcHS_A3242(ttdB)
ECMEcSMS35_3354(ddtA) EcSMS35_3355(ttdB)
ECYECSE_3342 ECSE_3343
ECRECIAI1_3209(ttdA) ECIAI1_3210(ttdB)
ECQECED1_3730(ttdA) ECED1_3731(ttdB)
EUMECUMN_3544(ttdA) ECUMN_3545(ttdB)
ECTECIAI39_3557(ttdA) ECIAI39_3558(ttdB)
EOCCE10_3590(ttdA) CE10_3591(ttdB)
EBRECB_02931(ttdA) ECB_02932(ttdB)
EBLECD_02931(ttdA) ECD_02932(ttdB)
EBEB21_02881(ttdA) B21_02882(ttdB)
EBDECBD_0679 ECBD_0680
ECIUTI89_C3497(ttdA) UTI89_C3498(ttdB)
EIHECOK1_3492(ddtA) ECOK1_3493(ttdB)
ECZECS88_3459(ttdA) ECS88_3460(ttdB)
ECCc3812(ttdA) c3813(ttdB)
ELOEC042_3355(ttdA) EC042_3356(ttdB)
ELNNRG857_15245 NRG857_15250
ESEECSF_2905 ECSF_2906
ECLEcolC_0637 EcolC_0638
EKOEKO11_0656 EKO11_0657
EKFKO11_07405(ttdB) KO11_07410(ttdA)
EABECABU_c34800(ttdA) ECABU_c34810(ttdB)
EDHEcDH1_0639
EDJECDH1ME8569_2958(ttdA)
ELUUM146_00990 UM146_00995
ELWECW_m3328(ttdA) ECW_m3329(ttdB)
ELLWFL_16260(ttdA) WFL_16265(ttdB)
ELCi14_3507(ttdA) i14_3508(ttdB)
ELDi02_3507(ttdA) i02_3508(ttdB)
ELPP12B_c3157(ddtA) P12B_c3158(ttdB)
ELFLF82_2330(ttdA) LF82_2331(ttdB)
ECOLLY180_15800 LY180_15805
ECOIECOPMV1_03379(ttdA_2) ECOPMV1_03380(ttdB)
ECOJP423_17300 P423_17305
EFEEFER_3208 EFER_3209(ttdA)
EALEAKF1_ch2866c(ttdB) EAKF1_ch2867c(ddtA)
STYSTY3534(ttdB) STY3535(ttdA)
STTt3269(ttdB) t3270(ttdA)
SEXSTBHUCCB_34570 STBHUCCB_34580
SENTTY21A_16580 TY21A_16585
STMSTM3354 STM3355
SEOSTM14_4046 STM14_4047
SEVSTMMW_33521
SEYSL1344_3326(ttdB) SL1344_3327(ttdA)
SEMSTMDT12_C34120 STMDT12_C34130
SEJSTMUK_3340 STMUK_3341
SEBSTM474_3514 STM474_3515
SEFUMN798_3647(ttdB) UMN798_3648(ttdA)
SETUSTU288_16990 STU288_16995
SETCCFSAN001921_00215 CFSAN001921_00220
SENRSTMDT2_32461(ttdB) STMDT2_32471(ttdA)
SENDDT104_33461(ttdB) DT104_33471(ttdA)
SENICY43_17465 CY43_17470
SEENSE451236_22885 SE451236_22890
SPTSPA3221(ttdB) SPA3222(ttdA)
SEKSSPA3008 SSPA3009
SPQSPAB_04180 SPAB_04181
SEISPC_3424(ttdB) SPC_3425(ttdA)
SECSCH_3292(ttdB) SCH_3293(ttdA)
SEHSeHA_C3652 SeHA_C3653
SHBSU5_03838 SU5_03839
SENHCFSAN002069_15395 CFSAN002069_15400
SEEHSEEH1578_02870 SEEH1578_02875
SEESNSL254_A3617 SNSL254_A3618
SENNSN31241_44780 SN31241_44790
SEWSeSA_A3546 SeSA_A3547
SEASeAg_B3545 SeAg_B3546
SENSQ786_16355 Q786_16360
SEDSeD_A3714 SeD_A3715
SEGSG3244 SG3245
SELSPUL_3364 SPUL_3365
SEGASPUCDC_3350 SPUCDC_3351
SETSEN3187 SEN3188
SENAAU38_16240 AU38_16245
SENOAU37_16440 AU37_16445
SENVAU39_16440 AU39_16445
SENQAU40_18290 AU40_18295
SENLIY59_16850 IY59_16855
SENJCFSAN001992_16775 CFSAN001992_16780
SEECCFSAN002050_23740 CFSAN002050_23745
SEEBSEEB0189_003085 SEEB0189_003090
SEEPI137_16060 I137_16065
SENBBN855_34310(ttdB) BN855_34320
SENEIA1_16250 IA1_16255
SENCSEET0819_00375 SEET0819_00380
SBGSBG_2799(ttdA) SBG_2800(ttdB)
SBZA464_3241 A464_3242
SBVN643_13955 N643_13960
SALZEOS98_02510 EOS98_02515
SFLSF3102(ttdA) SF3103(ttdB)
SFXS3307(ttdA) S3308(ttdB)
SFVSFV_3101(ttdA) SFV_3102(ttdB)
SFESFxv_3407(ttdA) SFxv_3408(ttdB)
SFNSFy_4425 SFy_4426
SFSSFyv_4502 SFyv_4503
SFTNCTC1_03359(ddtA) NCTC1_03360(ttdB)
SSNSSON_3198(ttdA) SSON_3199(ttdB)
SBOSBO_2919(ttdA) SBO_2920(ttdB)
SBCSbBS512_E3495(ddtA)
SDZAsd1617_04332 Asd1617_04333
SHQA0259_19050 A0259_19055
ENFAKI40_0047 AKI40_0048
KPNKPN_03639 KPN_03640
KPUKP1_4954(ttdB) KP1_4955(ttdA)
KPPA79E_0473 A79E_0474
KPYKPNIH31_23185 KPNIH31_23190
KPTVK055_3837 VK055_3838(ttdB)
KPXPMK1_01147(ttdB) PMK1_01148(ttdA)
KPNKBN49_0480 BN49_0481
KVAKvar_0459 Kvar_0460
KPEKPK_0481(ddtA) KPK_0482(ttdB)
KPKA593_08385 A593_08390
KVDKR75_05735 KR75_05740
KVQSP68_12350 SP68_12355
KOXKOX_03975 KOX_03980
KOEA225_5250 A225_5251
KOYJ415_05795 J415_05800
KOMHR38_02515 HR38_02520
KOKKONIH1_26475 KONIH1_26480
KOCAB185_09810 AB185_09815
EAEEAE_04565 EAE_04570
KQVB8P98_02490 B8P98_02495
KLLBJF97_26145 BJF97_26150
KARLGL98_02435(ttdA) LGL98_02440(ttdB)
KGRJJJ10_02600(ttdA) JJJ10_02605(ttdB)
RTGNCTC13098_04548(ttdB) NCTC13098_04549(ttdA)
CROROD_36061(ttdA) ROD_36071(ttdB)
CKOCKO_04451 CKO_04452
CFDCFNIH1_02510 CFNIH1_02515
CBRAA6J81_20690 A6J81_20695
CWECO701_01210 CO701_01215
CYOCD187_03570 CD187_03575
CPOTFOB25_14905(ttdB) FOB25_14910(ttdA)
CFQC2U38_21920 C2U38_21925
CSEDJY391_19080(ttdA) JY391_19085(ttdB)
CAMAF384_24965 F384_24970
CAFAL524_23235 AL524_23240
CIFAL515_19890 AL515_19895
CFARCI104_03725 CI104_03730
CIRC2U53_06080 C2U53_06085
CIEAN232_08015 AN232_08020
CPARCUC49_15820 CUC49_15825
CTELGBC03_27165(ttdA) GBC03_27170(ttdB)
CITZE4Z61_20380(ttdB) E4Z61_20385(ttdA)
CARSE1B03_22600(ttdA) E1B03_22605(ttdB)
SYMK6K13_00575(ttdA) K6K13_00580(ttdB)
ASUBNLZ15_16925(ttdB) NLZ15_16930(ttdA)
PDZHHA33_02495(ttdB) HHA33_02500(ttdA)
PSGCG163CM_40740(ttdA) G163CM_40750(ttdB)
EBCC2U52_08540 C2U52_08545
YMADA391_03165 DA391_03170
YHID5F51_19015 D5F51_19020
YCAF0T03_18295(ttdA) F0T03_18300(ttdB)
SFWWN53_22895 WN53_22900
DDCDd586_4030 Dd586_4031
CEDLH89_13340 LH89_13345
DFNCVE23_21515 CVE23_21520
DAQDAQ1742_00125(ttdB) DAQ1742_00126(ttdA)
BGJAWC36_22630 AWC36_22635
BNGEH206_08780 EH206_08785 EH206_11415 EH206_11420
BIZHC231_03425 HC231_03430 HC231_10465(ttdB) HC231_10470(ttdA)
PAOPat9b_4589 Pat9b_4590
MINTC7M51_03997(ttdA) C7M51_03998(ttdB)
MTHIC7M52_03034(ttdB) C7M52_03035(ttdA)
HPARAL518_07195 AL518_07200
PRAGEKN56_19905
LRINCTC12151_02671(ttdA_2) NCTC12151_02672(ttdB_2)
ASIASU2_10905 ASU2_10910
ASSASU1_10930 ASU1_10935
ALIGNCTC10568_01707(ttdA) NCTC10568_01708(ttdB)
PPWPputW619_2839 PputW619_2840
PPTPPS_2104 PPS_2105
PPXT1E_1252(ttdB) T1E_1253(ttdA)
PPUNPP4_33120(ttdA) PP4_33130(ttdB)
PMONX969_08845 X969_08850
PMOTX970_08505 X970_08510
PPJRK21_02737 RK21_02738
PSESPSCI_1372 PSCI_1373
PSETTHL1_3206 THL1_3207
PXAKSS93_13095(ttdA) KSS93_13100(ttdB)
PFAKKSS94_10505(ttdA) KSS94_10510(ttdB)
PSJPSJM300_07660 PSJM300_07665
AVNAvin_31190(ttdB) Avin_31200(ttdA)
AVLAvCA_31190(ttdB) AvCA_31200(ttdA)
AVDAvCA6_31190(ttdB) AvCA6_31200(ttdA)
ACCBDGL_000408(ttdB) BDGL_000409(ttdA)
ALCOTEC02_13285 OTEC02_13290
ACALBUM88_05495 BUM88_05500
ACDAOLE_13655 AOLE_13660
ALWFOB21_00030(ttdB) FOB21_00035(ttdA)
APRSBI364_08735
GAIIMCC3135_13785(ttdB) IMCC3135_13790(ttdA)
MMEMarme_0354 Marme_0355
MPCMar181_2688 Mar181_2689
MARSA8C75_13550 A8C75_13555
MARLHH196_00920(ttdA) HH196_00925(ttdB)
TAUTola_0413 Tola_0414
ZDFAN401_07905 AN401_07910
SVASVA_1858
AMAHDLM_1565
RPJN234_26045 N234_26050
CNCCNE_BB1p00490 CNE_BB1p00500(fumA)
REUReut_B5650 Reut_B5651
CBWRR42_m0449
BCTGEM_4194 GEM_4195
BYIBYI23_D015400 BYI23_D015410
BPHBphy_5632 Bphy_5633
PARABTO02_21335
PGISI6I06_21425
PACSFAZ98_25265
PEWKZJ38_22685 KZJ38_22690
PDQCL55_00014470
PTRPDCO17_02725 DCO17_02730
PANIDCO16_07910 DCO16_07915
PTXABW99_10940
PANDDRB87_06780 DRB87_06785
CABASBC2_17470(ttdB)
BPTBpet0402(ttdA) Bpet0403(ttdB)
BBROBAU06_07370
BFZBAU07_19095
BOHAKI39_07190
AXYAXYL_01147 AXYL_01148
AISBUW96_20490 BUW96_20495
ACHRC2U31_02405 C2U31_02410
ADYHLG70_26865 HLG70_26870
AKATKWG_02775 TKWG_02780
OUEI6G29_10505(ttdA) I6G29_10510(ttdB)
PARKLSG25_12735 LSG25_12740
ACRABSY15_4033(ttdB) BSY15_4034
VEIVeis_2510 Veis_2511
VAPVapar_5613 Vapar_5614
VPDVAPA_2c02830 VAPA_2c02840
HTNKI616_11930(ttdB) KI616_11935(ttdA)
DIHG7047_15660 G7047_15665
HARHEAR3330 HEAR3332
SUTTSUTMEG_16500(ttdA) SUTMEG_16510(ttdB)
SUTKFG381_02560(ttdA) FG381_02565(ttdB)
SWSI6J16_05590(ttdA) I6J16_05595(ttdB) I6J16_07360
URUDSM104443_03891(ttdB)
UPLDSM104440_03452(ttdB)
ATWC0099_14120 C0099_14125
AZAAZKH_p0064(ttdA) AZKH_p0065(ttdB)
ACOMCEW83_15575
BPRCD521_1236(ttdB) D521_1237 D521_1337
WSUWS1529(accA) WS1530
CCVCCV52592_1715(ttdB) CCV52592_1716(ttdA)
CCOCCC13826_1006(ttdA) CCC13826_1007(ttdB)
CGRACGRAC_1979(ttdB) CGRAC_1980(ttdA)
CRXCRECT_2015(ttdA) CRECT_2016(ttdB)
CMUCCMCT_1428(ttdA) CMCT_1429(ttdB)
CSHOCSHOW_0335(ttdB) CSHOW_0336(ttdA)
SBASulba_0014 Sulba_0015
SMULSMUL_0015(ttdA) SMUL_0016(ttdB)
SHALSHALO_0014 SHALO_0015
SULSSdiek1_0014 Sdiek1_0015
SULJSJPD1_0011 SJPD1_0012
SULTFA592_07260(ttdA) FA592_07265(ttdB)
DFIAXF13_13570
PAUUE8A73_032240
KMNHW532_09615 HW532_09620
RHTNT26_p10291 NT26_p10292
VGOGJW-30_1_00142(ttdB)
MRDMrad2831_5985 Mrad2831_5986
MNOMnod_8668 Mnod_8669
METIDK427_21080
MMESMMSR116_04805
JANJann_3970 Jann_3971
RPONG3256_11695 G3256_11700
SULIC1J05_16300 C1J05_16310
TOMBWR18_17170 BWR18_17175
RMMROSMUCSMR3_02043(ttdB) ROSMUCSMR3_02044(ttdA)
ROKRAK1035_1142 RAK1035_1143
RSPRSP_3145(ttdB) RSP_3146(ttdA)
RSHRsph17029_3882 Rsph17029_3883
RSKRSKD131_3317 RSKD131_3318
RBGBG454_16665 BG454_16670
RBZB9057_04015 B9057_04020
GCEKYE46_03230 KYE46_03235
SRFLHU95_07415 LHU95_07420
MAGamb3178 amb3179
ELIOKO353_01280 KO353_01285
NACINUH88_12345 NUH88_12350
PARHI5S86_15165(ttdB) I5S86_15170(ttdA)
BKOCKF48_05415 CKF48_05420
MSEMGMB29_06255(ttdA) GMB29_06260(ttdB)
LPLlp_1089(ttdB) lp_1090(ttdA)
LPJJDM1_0900(ttdB) JDM1_0901(ttdA)
LPTzj316_1124(ttdB) zj316_1125(ttdA)
LPSLPST_C0874(ttdB) LPST_C0875(ttdA)
LPRLBP_cg0862 LBP_cg0863
LPZLp16_0877 Lp16_0878
LPBSH83_04510 SH83_04515
LPXASU28_00790 ASU28_00795
LPGBB562_11845 BB562_11850
LARGLPA65_04410 LPA65_04415
LMALLM596_12365(ttdB) LM596_12370(ttdA)
LZYLZ3411_0347 LZ3411_0348
TEYGLW17_00155(ttdA) GLW17_00160(ttdB)
TKRC7K43_02285 C7K43_02290
SARJHH195_10920(ttdB) HH195_10925(ttdA)
RUMCK1_26540 CK1_26550
RIXRO1_30600 RO1_30610
RIMROI_33300 ROI_33310
CCOMI6K69_12480(ttdA) I6K69_12485(ttdB)
EHLEHLA_0522 EHLA_0523
RTORTO_23470 RTO_23480
CBOLCGC65_18405 CGC65_18410 CGC65_18415 CGC65_18420
DLOK5I24_13660(ttdA) K5I24_13665(ttdB)
EREEUBREC_3080 EUBREC_3081
ERTEUR_06780 EUR_06790
ERAERE_12820 ERE_12830
SWOSwol_1628 Swol_1629
PHARNCTC13077_01584(ttdB) NCTC13077_01585(ttdA)
VPRVpar_1291 Vpar_1292
VATB7L28_06460 B7L28_06465
VRM44547418_01374(ttdB) 44547418_01375(ttdA_1)
VDNNCTC11831_00531(ttdA_1) NCTC11831_00532(ttdB)
VNKVEIT17_05250 VEIT17_05260
SELEADJ74_01660 ADJ74_01665
SELOAXE86_08615 AXE86_08620
SELTBCS37_01945 BCS37_01950
PUFUFO1_3513 UFO1_3514
AFNAcfer_1346 Acfer_1347
AINAcin_0917(ttdA) Acin_0918(ttdB)
CARcauri_2301(ttdB) cauri_2302(ttdA)
CVTB843_10920 B843_10925
CFKCFRA_02600 CFRA_02605
CRLNCTC7448_00235(ttdA) NCTC7448_00236(ttdB)
CUWLH390_02455(ttdB) LH390_02460(ttdA)
RHARHA1_ro08823(ttdB) RHA1_ro08824
PACDEGX94_10715 EGX94_10720
ARDAXF14_03735 AXF14_03740
AHWNCTC11636_02000(ttdB) NCTC11636_02001(ttdA)
TSKHRI97_05015(ttdB) HRI97_05020(ttdA)
IAGIgag_0571 Igag_0572
TCBTCARB_0963 TCARB_0964
FFOFFONT_0542 FFONT_0543
CCAINAS2_0388
 » show all
Reference
1  [PMID:14342293]
  Authors
HURLBERT RE, JAKOBY WB.
  Title
TARTARIC ACID METABOLISM. I. SUBUNITS OF L(+)-TARTARIC ACID DEHYDRASE.
  Journal
J Biol Chem 240:2772-7 (1965)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.32
IUBMB Enzyme Nomenclature: 4.2.1.32
ExPASy - ENZYME nomenclature database: 4.2.1.32
BRENDA, the Enzyme Database: 4.2.1.32
CAS: 9014-40-8
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