| Entry |
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| Name |
(-)-endo-fenchol synthase;
(-)-endo-fenchol cyclase;
geranyl pyrophosphate:(-)-endo-fenchol cyclase
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| Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
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| Sysname |
geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-endo-fenchol-forming]
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| Reaction(IUBMB) |
geranyl diphosphate + H2O = (-)-endo-fenchol + diphosphate [RN: R02004]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
(3R)-Linalyl diphosphate is an intermediate in the reaction
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| History |
EC 4.2.3.10 created 1992 as EC 4.6.1.8, transferred 2000 to EC 4.2.3.10
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| Pathway |
| ec01110 | Biosynthesis of secondary metabolites |
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| Orthology |
| K15097 | (-)-endo-fenchol synthase |
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| Reference |
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| Authors |
Croteau R, Miyazaki JH, Wheeler CJ. |
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| Title |
Monoterpene biosynthesis: mechanistic evaluation of the geranyl pyrophosphate:(-)-endo-fenchol cyclase from fennel (Foeniculum vulgare). |
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| Journal |
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| Reference |
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| Authors |
Croteau R, Satterwhite DM, Wheeler CJ, Felton NM. |
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| Title |
Biosynthesis of monoterpenes. Stereochemistry of the enzymatic cyclization of geranyl pyrophosphate to (-)-endo-fenchol. |
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| Journal |
J Biol Chem 263:15449-53 (1988) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.2.3.10 |
| ExPASy - ENZYME nomenclature database: | 4.2.3.10 |
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| LinkDB |
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