Entry Name ent-isokaurene synthase;
Class Lyases;BRITE hierarchy
Sysname ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-isokaurene-forming)
Reaction(IUBMB) ent-copalyl diphosphate = ent-isokaurene + diphosphate [RN:
R09903 ]
Reaction(KEGG) Substrate ent-copalyl diphosphate [CPD:
C06089 ]
Product Comment Two enzymes of the rice sub-species Oryza sativa ssp. indica, OsKSL5 and OsKSL6, produce ent-isokaurene. A variant of OsKSL5 from the sub-species Oryza sativa ssp. japonica produces ent-pimara-8(14),15-diene instead [cf. EC
4.2.3.30 , ent-pimara-8(14),15-diene synthase].
History EC 4.2.3.103 created 2012
Pathway ec01110 Biosynthesis of secondary metabolites
Orthology K16082 ent-isokaurene synthase
Genes Taxonomy Reference Authors Xu M, Wilderman PR, Morrone D, Xu J, Roy A, Margis-Pinheiro M, Upadhyaya NM, Coates RM, Peters RJ
Title Functional characterization of the rice kaurene synthase-like gene family.
Journal Sequence Reference Authors Xu M, Wilderman PR, Peters RJ
Title Following evolution's lead to a single residue switch for diterpene synthase product outcome.
Journal Sequence Other DBs ExPASy - ENZYME nomenclature database: 4.2.3.103
LinkDB All DBs
