KEGG   ENZYME: 5.1.3.31
Entry
EC 5.1.3.31                 Enzyme                                 
Name
D-tagatose 3-epimerase;
L-ribulose 3-epimerase;
ketose 3-epimerase
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
Sysname
D-tagatose 3-epimerase
Reaction(IUBMB)
(1) D-tagatose = D-sorbose [RN:R10818];
(2) D-psicose = D-fructose [RN:R10817]
Reaction(KEGG)
R10817 R10818
Substrate
D-tagatose [CPD:C00795];
D-psicose [CPD:C06468]
Product
D-sorbose [CPD:C00764];
D-fructose [CPD:C00095]
Comment
The enzymes isolated from the bacteria Pseudomonas cichorii [2], Pseudomonas sp. ST-24 [1], Rhodobacter sphaeroides [3] and Mesorhizobium loti [4] catalyse the epimerization of various ketoses at the C-3 position, interconverting D-fructose and D-psicose, D-tagatose and D-sorbose, D-ribulose and D-xylulose, and L-ribulose and L-xylulose. The specificity depends on the species. The enzymes from Pseudomonas cichorii and Rhodobacter sphaeroides require Mn2+ [2,3].
History
EC 5.1.3.31 created 2014
Orthology
K18910  D-psicose/D-tagatose/L-ribulose 3-epimerase
Genes
METYMRY16398_18130
STEMCLM74_02750
VNIVIBNI_B2134
VSHBSZ05_18720
PEZHWQ56_21710
PLZS4054249_14065
PXIJ5O05_19055
PSYPCNPT3_12810
CEBB0D95_16695
CEKD0B88_14095
HJABST95_04425 BST95_12590
HALCEY643_09855 EY643_18065
MMTMetme_2524
MDHAYM39_05640
MKOMKLM6_1146
MPSYCEK71_08015
THIPN838_29775
HAFC8233_04545
HOLHORIV_69060
CMAIBFX80_10770
THINCRN91_08470
RSCRCFBP_20181
RSLRPSI07_2117
RSNRSPO_c02115
RSYRSUY_16820
RSGJK151_10265
CNCCNE_1c28340
BCENDM39_5554
BMUBmul_3563
BMKDM80_4951
BSTGWT74_30375
BGLbglu_2g16410
BGUKS03_4299
BUGBC1001_0668
BGDbgla_2g21700
BGOBM43_5843
BYIBYI23_A020710 BYI23_C011990
BUEBRPE67_CCDS14600
BGPBGL_2c21880
BPLAbpln_2g22110
BUMAXG89_26010 AXG89_26680 AXG89_39165
BUIAX768_21195
BCAIK788_0000113
PSPWBJG93_09715
PHSC2L64_30420
PTERC2L65_27135
PCAFDSC91_000120
PMEGFNZ07_17930
PLGNCTC10937_04633
BUOBRPE64_CCDS02530
RHYRD110_21165
RHGEXZ61_14210
VEIVeis_3271
DACDaci_0782
DELDelCs14_5754
DTSBI380_20805
DHKBO996_03955
DLAI6G47_20745
LIML103DPR2_00913
HYBQ5W_00980 Q5W_22820
HYNF9K07_17815
MLOmll3360 mll3595
MLNA9174_07595 A9174_08640 A9174_16425
MCIMesci_1491 Mesci_1666 Mesci_2436
MOPMesop_1534 Mesop_1710 Mesop_3167
MAMMesau_01552 Mesau_01736
MAMOA6B35_23710 A6B35_29250
MESWA9K65_007645 A9K65_008745 A9K65_012765
MESMEJ066_03060 EJ066_03250 EJ066_17540
MHUAMCHK_3614 MCHK_4785 MCHK_4976
MJREB229_07810 EB229_08805 EB229_16650
MERDEB233_07715 EB233_08995 EB233_13835
MESRFGU64_11255
MESOBSQ44_01040
HOEIMCC20628_03197
PHTBLM14_20585 BLM14_28575
RPODE0E05_10855
NIYFQ775_16790
NKIKW403_07560 KW403_17410
SMESM_b20488 SMa1354
SMKSinme_3703 Sinme_5929
SMQSinmeB_4198 SinmeB_6248
SMXSM11_pC0916 SM11_pD1142
SMIBN406_04469 BN406_06197
SMEGC770_GR4pC0646 C770_GR4pD1134
SMELSM2011_a1354 SM2011_b20488
SMERDU99_22340 DU99_30880
SMDSmed_0189 Smed_3635 Smed_5868
RHINGR_b11570
SFHSFHH103_06000
SFDUSDA257_c17260 USDA257_c31550
SIXBSY16_4547 BSY16_5610 BSY16_5683
SAMESAMCFNEI73_pC0749
SINOSS05631_b52670 SS05631_b60350
EADOV14_a0256 OV14_b0219 OV14_b1208
EAHFA04_21405 FA04_32495
EMXFKV68_13515
ATUAtu4748 Atu4750(dpe)
ARAArad_12385 Arad_7080 Arad_9421
ATAAWN88_06825 AWN88_06835
AROB0909_13780 B0909_13790
AGTEYD00_18345 EYD00_18355
ALFCFBP5473_22900 CFBP5473_22910
AVQHRR99_19475 HRR99_19485 HRR99_20215
RETRHE_PF00383
RELREMIM1_PF00526
REIIE4771_PD00392
RLERL0640 pRL120195 pRL120584
RLTRleg2_0259 Rleg2_4619
RLGRleg_0288 Rleg_4979 Rleg_5314
RLBRLEG3_08105 RLEG3_09580 RLEG3_11330
RLURLEG12_11035 RLEG12_12650
RTRRTCIAT899_PC06145
RIRBN877_II0941(dpe) BN877_II0943
RPUSCFBP5875_18470 CFBP5875_18480
RHLLPU83_pLPU83d0377 LPU83_pLPU83d1620 LPU83_pLPU83d1622
RGARGR602_PC00423 RGR602_PC01248 RGR602_PC01887
RHVBA939_22530 BA939_22540
RJGCCGE525_28665 CCGE525_30445
RHRCKA34_25125
RGRFZ934_22555
RADCO657_01360 CO657_28525
RIIFFM53_009985 FFM53_025775 FFM53_027445 FFM53_032190
RHIDFFM81_017945 FFM81_024420 FFM81_031275
RBQJ2J99_32080
RLNJ0663_23770
RBANJ2J98_23065
RRGJ3P73_03780 J3P73_24935 J3P73_26915
NGLRG1141_PA14380
NGGRG540_PA16120
NEOCYG48_14470
NENNCHU2750_50190(dpe) NCHU2750_50210(dpe)
SHZshn_02665 shn_26005 shn_32275
SOJK6301_18835 K6301_21570 K6301_22180
KAIK32_10170(dpe) K32_22710 K32_36220 K32_40870
OCHCES85_4526
OCRHGK82_02470
BBETF8237_26575
VGOGJW-30_1_01412
BVVBHK69_29495
BOIBLM15_17310
BOFFQV39_14805
STARG3545_22400 G3545_27685
LNEFZC33_02690 FZC33_02800 FZC33_06310 FZC33_22685
MCHMchl_2911
MZAB2G69_20955
METDC0214_15075
MOCBB934_21425 BB934_34660
CHELAL346_11300 AL346_20765
CDQBOQ54_03505 BOQ54_18525
DEQXM25_21985
YTIFNA67_03435
PLEOOHA_1_04250
HDIHDIA_0684
MEYTM49_19265
MAADAZF01_07150 AZF01_07335
MMEDMame_03157
MLUTJET14_08030 JET14_08205
AUAM673_19160 M673_21385
AALAIGS74_12725 IGS74_14295
AALMLUX29_14615 LUX29_16170
PSINCAK95_17145
NOHG5V57_27210
PPHRAPZ00_11215 APZ00_11520
SIWGH266_02850
PHRC6569_12610
PSTGE8M01_02200
LIZLGH83_13620
RUTFIU92_22040
RDERD1_3873
RLIRLO149_c005620
DSHDshi_0533
MALGMALG_00913 MALG_04868
TPROGa0080559_TMP2188 Ga0080559_TMP3730
SULZC1J03_06080
SULIC1J05_03110
SAGUCDO87_19305 CDO87_20930
RMHLVO79_11505
MALUKU6B_06160
HATRC74_10995
RSPRSP_3671
RSHRsph17029_3406
RSQRsph17025_3261
RSKRSKD131_3901
CAZTLV780_15200
PAROCUV01_14045
PPANESD82_08985
RMBK529_015670
LVSLOKVESSMR4R_02504
GEHHYN69_06135
TAWEI545_04520
SALOEF888_13960
SEDIEBB79_22915
LITFPZ52_00340 FPZ52_11885
PPRUFDP22_22460
HDHG5B40_05740
NSMJO391_16615
NOTC7W88_20505
PNSA9D12_04060
GTIFXF46_02505
ABGAsbog_00446
RGIRGI145_22210
NCHA0U93_11755
LCKHN018_02945 HN018_05720
SRFLHU95_18875
SHUMSTHU_23520
SVCSTVA_27090
STELSTAQ_21190
ABSAZOBR_50004
ABQABAZ39_14865
ABFAMK58_15710
SKTIGS68_32570
SMUCJL100_033630
SROEJL101_031260
FERFNB15_02720
THACCSC3H3_22520
MAGQMGMAQ_3684
BIQAN935_02885
BALMBsLM_0584
BEOBEH_05835
OCNCUC15_16775
LMACI6G82_12080
LAOAOX59_10575
MSEMGMB29_22545
SEDDERJ70_15170
GYMGYMC10_4656
PAEHH70357_17810
PSWUSY83_05990
PIBBBD41_01800
PVOPVOR_25051
PPSCEHS13_30735 EHS13_32530
PBKBack11_03730 Back11_03790
COHNKCTCHS21_15520 KCTCHS21_60540
SPSYAZE41_19135
NTRB0W44_16795
KEBGXN75_05770
EGVEGCR1_17395
CLSCXIVA_15900(IolE)
CLBClo1100_3083 Clo1100_3263
CSQCSCA_0424
CDRKB9W14_16375
CCECcel_0941
CCELCCDG5_1948
FPLAA4U99_17845
RUSRBI_I00720
FPRFP2_24930
CAPREQM14_02830
ACOLK5I23_05420 K5I23_11840
ROBCK5_09670
LACYA4V08_19625 A4V08_20610 A4V08_25180
CSCIHDCHBGLK_00678 HDCHBGLK_00680 HDCHBGLK_03482
BPRLCL2_01610 CL2_02560
ARFAR1Y2_0028 AR1Y2_3038 AR1Y2_3102
ACACEYQ97_02340 EYQ97_02550 EYQ97_06320 EYQ97_13045
ANRAna3638_15530 Ana3638_20240
CBOLCGC65_05515 CGC65_27435
SINTK5I26_08885
QDOH9Q78_06845 H9Q78_13760
CMIUB1H56_02695 B1H56_07390 B1H56_07570 B1H56_11560 B1H56_11685 B1H56_13460 B1H56_13865
VGUHYG85_22255
VPYHZI73_20645
LASAL9O85_14350
IFNGM661_06865
ERDG7062_07145 G7062_10260
CIUG4D55_15935
LCGL3BBH23_08620
ERBA4V01_17940 A4V01_18865
MTYMTOK_13240
SALBXNR_0898
SCBSCAB_79471
SBHSBI_01788
SDVBN159_2555
STRCAA958_13980 AA958_29750
SKYD0C37_05945
SLSSLINC_8346
SALFSMD44_00673
SKACP970_01030
SSPBCP982_36650
SATAC5746_02870
SROIIAG44_01735
CCAPAES38_02495 AES38_02500
MIMAKG07_07390 AKG07_10865
MIPAXH82_01220 AXH82_04485
MICRBMW26_11930 BMW26_15605
MFOLDXT68_15025
MLVCVS47_03130
MWAE4K62_09280
MSEDE3O41_03650
MOYCVS54_03329
MSFIT882_14745
MCAWF6J84_13210 F6J84_14175
MLZF6J85_16430 F6J85_16445
MBINLXM64_14860
RTNA6122_2903
RIAC7V51_12145 C7V51_12150
CUBBJK06_03935
AGYATC03_03180
AGMDCE93_02220
AMAUDSM26151_05080
ASOIMTP13_01365
CARTPA27867_3432 PA27867_3433
CPHYB5808_17995 B5808_18000
AUMAURMO_01292
MALKMalAC0309_2552
MYLC3E77_13255
HUMDVJ78_04535 DVJ78_04585
LYDD7I47_02975
PLAPEAO79_04430
LEULeucomu_01265
LTREVS81_10180
AGGC1N71_13590
HEAHL652_15330 HL652_15335 HL652_17515
AGXAGREI_0282 AGREI_0283
SUBTKPL76_03265 KPL76_03270
ARRARUE_c20230
ARZAUT26_17140
ARNCGK93_11445
ARXARZXY2_155
ACRYAC20117_08240
AAGINCTC2676_1_00275 NCTC2676_1_02144
ASUFMNQ99_00120
AAUAAur_1891
KRSEQG70_10590
BRZCFK38_11650
BRRC1N80_04160
LMOIVV02_00500 VV02_04345
IVAIsova_2196 Isova_2984
CETB8281_09645
CCEUCBR64_01480
OEKFFI11_017255
PSEIGCE65_11330
PEIH9L10_01065
SERJSGUI_0940
SERWFY030_04555 FY030_14440
ORZFNH13_07635
BLINBLSMQ_0068
GEZFE251_00700
RHALLQF10_06510
PAUSNCTC13651_02133
MPHMLP_04780
MICGGJV80_21215
TFABW733_03775
TEZBKM78_06355 BKM78_11605
TLATLA_TLA_01284 TLA_TLA_02338
NSNEXE58_02845
NROK8W59_17195
NPCKUV85_00200
NDANdas_4059
NALB005_1215
NFEHUT17_04380
NOABKM31_13325
NOWGBF35_14930
NGNLCN96_29060
NMLNamu_1536
MMARMODMU_2902 MODMU_5481
SVISvir_12330
SACCEYD13_06740
AABA4R43_39160
AMYYYIM_38700
AACDLWP59_13420
KPHYAOZ06_34620
LEDBBK82_39765
AHMTL08_17425
ACTIUA75_21195
ACADUA74_20700
AHGAHOG_18450
ACTAC1701_01795
PMADBAY61_12155
MICHFJK98_13500
MCABHXZ27_06925
MSAGGCM10017556_04500
VMAVAB18032_18335
VERHUT12_14715
PRYPrubr_00690 Prubr_06700
CATICS0771_58310
CCAZCOUCH_19160
SNASnas_4652
GLYK3N28_07325
FLHEJ997_11795
PLIMPHILAsVB114_05000
ABAMB1s21122_02315
NABB1sIIB91_01380
JTLM6D93_18585
RUBGBA63_01875
EUZDVS28_a0808
SYZMYO_110780
SYYSYNGTS_1069(sll1304)
SYTSYNGTI_1069(sll1304)
SYSSYNPCCN_1068(sll1304)
SYQSYNPCCP_1068(sll1304)
SYJD082_11260
SYOC7I86_05545
SYNESyn6312_2122
SYNPSyn7502_01681
GENGM3709_2819
CYJCyan7822_5649
OACOscil6304_5533
RSINB6N60_03739
ABAOBEQ56_02070
CAPCLDAP_22550
TRATrad_2158
MRBMrub_1698
MREK649_14070
MSVMesil_0036
MTAIMtai_v1c12600
MHDMarky_1098
VBHCMV30_02125
OLEK0B96_04280 K0B96_13950
CAACaka_0707
ROOG5S37_26005
LUOHHL09_07575 HHL09_19000
LAMBKBB96_00505
RBARB11728
PSLPsta_0700
PIRVN12_14195
RULUC8_02530
RMLFF011L_11380
MFFMFFC18_09150(iolI_1)
AHELQ31a_64540
LCREPla8534_31580
AAGGETAA8_61620
BVOPan97_48500
RLCK227x_48080
TTFTHTE_3776
LPAVPLANPX_1471
PNDPla175_14070
PLMPlim_0391 Plim_4185
PEHSpb1_11580
PBSPlabr_0077
PLSVT03_03385
PLHVT85_17645 VT85_19445
FMRFuma_04265
GMRGmarT_29260 GmarT_35380
GIMF1728_00265
GPNPan110_28090 Pan110_33410
MRIMal4_41680
SDYNMal52_42410 Mal52_49880
PLONPla110_31290 Pla110_34380
GESVT84_08900 VT84_19690(iolI_2)
GOGC1280_07445 C1280_17375
GMSSOIL9_07520
TIMGMBLW1_17630
LRSPX52LOC_00790
FTJFTUN_5876 FTUN_6635
ULIETAA1_20970 ETAA1_53650 ETAA1_59940(iolI_3)
TSPHKIH39_04155
IPAIsop_0568
SACISinac_5698
PBORBSF38_02095
AGVOJF2_23940
HBSIPV69_12660
VBCC5Q97_16425 C5Q97_17955
OCKEXM22_17730
SBUSpiBuddy_0540 SpiBuddy_2415
SGPSpiGrapes_1435 SpiGrapes_1795 SpiGrapes_2373
SASSMUG09_03120
TSAAciPR4_2305
ABASACPOL_4053 ACPOL_4615
PFERIRI77_21880
ABACLuPra_02409
STRSterm_0653
PPNPalpr_0104
PDIBDI_2307
PARCCI960_17715
RBARAWN76_003905 AWN76_014945
CHITFW415_13415 FW415_19430
ARACE0W69_012675
PSEGD3H65_06050
FLCKJS93_02920 KJS93_06950
HHYHalhy_2208 Halhy_5266
PHEPhep_3760
PCMAY601_0264
PGSCPT03_13205
SHTKO02_09145 KO02_11615
SMIZ4412673_03704 4412673_03975
SPHEGFH32_10980
SDJNCTC13534_05143 NCTC13534_05200 NCTC13534_05553
AGDFRZ59_01970 FRZ59_02110 FRZ59_02770
SBXCA265_12260
CMRCycma_1174 Cycma_4824
CAMUCA2015_1081 CA2015_4633
ALMAO498_11830 AO498_15905
SLISlin_0509 Slin_1263
SRDSD10_05995 SD10_20405
SMONAWR27_05675 AWR27_23290
SPIRCWM47_12175 CWM47_28965
SPIKEXU85_06785 EXU85_23685
SPIBG8759_19575 G8759_22300 G8759_26250
STAEHNV11_07645 HNV11_09145
SRHOHH216_13400
PSEZHME7025_00737
RHOZGXP67_15010 GXP67_16445
DFEDfer_3174 Dfer_4299 Dfer_4538 Dfer_4701
DSNHWI92_14980 HWI92_16240
RSIRunsl_0649 Runsl_1322
RUNDR864_15455 DR864_22240
RUPDTQ70_12975 DTQ70_19960
EOLEmtol_1244 Emtol_1284
FAEFAES_1761
FIBA6C57_00580 A6C57_15130
ALSDJ013_08970 DJ013_19955
ADDHUW48_06280 HUW48_14970
ASWUHUW51_05805 HUW51_08365 HUW51_09595
FBTD770_12940
FJOFjoh_4045
FCMBIW12_14660
ZPRZPR_1902
FBCFB2170_14643
MARMYQ22_00835
MARTBTR34_00810
MARBCJ263_17270
MAREEJ994_11790
ZGAZOBELLIA_919
AALGAREALGSMS7_03197 AREALGSMS7_04767
FEKC1H87_20440
EMARD1013_05000 D1013_10415
ASAGFGM00_05425
CIHATE47_06560
CHHA0O34_20265
CARHEGY05_11770
CJTEG359_04990
CBENEG339_20075
CGLENCTC11432_01148
CBPEB354_09465
EZEKI430_05360
CHYDH4K34_05970
MPGTheba_1025
MINFMESINF_0132
ALAMRT761_00419 RT761_00601(dpe) RT761_00669 RT761_01054 RT761_02213
HJEHacjB3_19043
HALJG9465_19195
SRUBC2R22_23745
CMACmaq_0649
 » show all
Reference
1
  Authors
Itoh, H., Okaya, H., Khan, A. R., Tajima, S., Hayakawa, S., Izumori, K.
  Title
Purification and characterization of D-tagatose 3-epimerase from Pseudomonas sp. ST-24.
  Journal
Biosci Biotechnol Biochem 58:2168-2171 (1994)
Reference
2  [PMID:17936787]
  Authors
Yoshida H, Yamada M, Nishitani T, Takada G, Izumori K, Kamitori S
  Title
Crystal structures of D-tagatose 3-epimerase from Pseudomonas cichorii and its complexes with D-tagatose and D-fructose.
  Journal
J Mol Biol 374:443-53 (2007)
DOI:10.1016/j.jmb.2007.09.033
Reference
3  [PMID:19205890]
  Authors
Zhang L, Mu W, Jiang B, Zhang T
  Title
Characterization of D-tagatose-3-epimerase from Rhodobacter sphaeroides that converts D-fructose into D-psicose.
  Journal
Biotechnol Lett 31:857-62 (2009)
DOI:10.1007/s10529-009-9942-3
  Sequence
Reference
4  [PMID:23470755]
  Authors
Uechi K, Takata G, Fukai Y, Yoshihara A, Morimoto K
  Title
Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production.
  Journal
Biosci Biotechnol Biochem 77:511-5 (2013)
DOI:10.1271/bbb.120745
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.1.3.31
IUBMB Enzyme Nomenclature: 5.1.3.31
ExPASy - ENZYME nomenclature database: 5.1.3.31
BRENDA, the Enzyme Database: 5.1.3.31
LinkDB

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