KEGG   ENZYME: 5.4.1.4
Entry
EC 5.4.1.4                  Enzyme                                 
Name
D-galactarolactone isomerase;
GLI
Class
Isomerases;
Intramolecular transferases;
Transferring acyl groups
Sysname
D-galactaro-1,5-lactone isomerase (D-galactaro-1,4-lactone-forming)
Reaction(IUBMB)
D-galactaro-1,5-lactone = D-galactaro-1,4-lactone [RN:R10846]
Reaction(KEGG)
R10846
Substrate
D-galactaro-1,5-lactone [CPD:C20889]
Product
D-galactaro-1,4-lactone [CPD:C20896]
Comment
The enzyme, characterized from the bacterium Agrobacterium fabrum strain C58, belongs to the amidohydrolase superfamily. It participates in the degradation of D-galacturonate.
History
EC 5.4.1.4 created 2015
Pathway
ec00053  Ascorbate and aldarate metabolism
ec01100  Metabolic pathways
Orthology
K18982  D-galactarolactone isomerase
Genes
LEH: C3F35_03335
LAZ: A8A57_10890
SRZ: AXX16_3563
RBAD: H2866_21825
PPUD: DW66_2032
POR: APT59_07800
PPSL: BJP27_22685
PCH: EY04_12420
PCHP: C4K32_2662
PSW: LK03_17540
MNK: RE428_41070
CSA: Csal_2475
HEL: HELO_3406
HAK: KO116_03369
HAM: HALO3642
HSV: HNO53_00190
HCAM: I4484_00190
HSX: HNO51_00190
HTX: EKK97_00195
COBB: H2O77_06835
COBD: U0O11_06495
KUS: B9G99_13550
KMA: B9H00_01440
MME: Marme_0066
MPC: Mar181_2907
MARS: A8C75_18895
SALN: SALB1_0469
CHIZ: HQ393_04195
RPJ: N234_10395 N234_23755
RMN: TK49_18935
RIN: ACS15_5732
CBW: RR42_m2140
CGD: CR3_4200
BTE: BTH_II0981
BTQ: BTQ_4276
BTJ: BTJ_5314
BTZ: BTL_3776
BTV: BTHA_4107
BTHE: BTN_3882
BTHM: BTRA_3773
BTHA: DR62_3924
BTHL: BG87_3732
BUR: Bcep18194_B1313
BCM: Bcenmc03_5772
BCH: Bcen2424_4532
BCJ: BCAM1714
BCEO: I35_5584 I35_6476
BMUL: NP80_4821
BCT: GEM_3925
BCED: DM42_5393 DM42_6235
BCEP: APZ15_23450
BCON: NL30_03600 NL30_16735
BDF: WI26_21685
BLAT: WK25_27295
BTEI: WS51_01410
BSEM: WJ12_28490 WJ12_31200
BPSL: WS57_05430
BMEC: WJ16_18575 WJ16_27325
BSTL: BBJ41_21935
BANN: JFN94_26560
BAEN: L3V59_22455
BGF: BC1003_3951
BGD: bgla_2g19130
BGO: BM43_5639 BM43_6429
BYI: BYI23_C002260 BYI23_D000940
BUE: BRPE67_CCDS03300 BRPE67_CCDS09960 BRPE67_DCDS02970
BGP: BGL_1c01060 BGL_2c14960
BPLA: bpln_1g01070 bpln_2g15680
BUM: AXG89_13020
BUI: AX768_06820
BPH: Bphy_6996
BUZ: AYM40_21280
BFN: OI25_5017 OI25_6054
BCAI: K788_0000471 K788_0002246 K788_0004196
PSPW: BJG93_29755
PARB: CJU94_34335
PHS: C2L64_11025 C2L64_41940
PTER: C2L65_10170
PCJ: CUJ87_26120
PMEG: FNZ07_18360
PACP: FAZ97_26390
PACS: FAZ98_29290
PKF: RW095_16980
PAND: DRB87_17105
PLG: NCTC10937_02739
CABA: SBC2_07840(pmdD)
BUO: BRPE64_DCDS00450 BRPE64_ECDS02580
CABK: NK8_51520 NK8_76250
BPT: Bpet3816
BBRO: BAU06_08280 BAU06_14765 BAU06_21945
BFZ: BAU07_22085
BOH: AKI39_00275 AKI39_03710 AKI39_14135
BGV: CAL12_24060
AXX: ERS451415_04002
ADT: APT56_18615
ASW: CVS48_11605
ODI: ODI_R3125
RHY: RD110_00370
POL: Bpro_4571
POS: DT070_03815
POO: F7R28_05625
ACIP: CBP36_20315
ACIS: CBP35_20390
AMON: H9L24_12530
VPD: VAPA_2c01710
VAA: AX767_13000
VAM: C4F17_24085 C4F17_31760
RGU: A4W93_03760
HSZ: ACP92_22255
HHT: F506_02770
HRB: Hrubri_4462
HEE: hmeg3_05925
HHF: E2K99_23465
HFR: G5S34_14855 G5S34_14890 G5S34_15275
XYK: GT347_00835 GT347_10910
URU: DSM104443_00896(pmdD_1) DSM104443_02549(pmdD_3)
UPL: DSM104440_01301
BEBA: BWI17_00120 BWI17_14235
MES: Meso_1945
RPOD: E0E05_16975
EAD: OV14_a1862
EAH: FA04_25480
ECAA: J3R84_28140
ENP: JVX98_06875
ATU: Atu3138
ATA: AWN88_10715
AGR: AGROH133_10631
ATF: Ach5_29930(gli)
AGC: BSY240_2212
AGT: EYD00_14435
ALF: CFBP5473_00085
ARUI: G6M88_08660
AVQ: HRR99_00465
ASAL: CFBP5507_23265
RIR: BN877_II0122
RPUS: CFBP5875_14585
ACUC: KZ699_15125
ALEG: CFBP4996_14965
RHV: BA939_26330
RJG: CCGE525_33305
ROY: G3A56_17320
RROS: D4A92_09810
RRHO: PR018_24160
RTU: PR017_25000
ARO: B0909_22905
NGL: RG1141_CH22500
NGG: RG540_CH23340
NEO: CYG48_08765
NEN: NCHU2750_21880(gli)
NPM: QEO92_11845
SZO: K8M09_21625
PDES: FE840_018510
BGQ: X265_38990
BGZ: XH91_38190
VGO: GJW-30_1_00973 GJW-30_1_01609
BAPI: BBC0122_003850
XAU: Xaut_3369
STAR: G3545_10550
MMES: MMSR116_11655
RHZ: RHPLAN_11390 RHPLAN_13870
PHL: KKY_3039
AALA: IGS74_08755
JIE: OH818_20380
BRN: D1F64_18270
PSTG: E8M01_07655
RPON: G3256_05785
YPAC: CEW88_05340
YAN: AYJ57_18570
TPRO: Ga0080559_TMP358
SPSE: SULPSESMR1_04920
RID: RIdsm_00831
PAMN: JCM7685_3051
PPAN: ESD82_14255
PSEB: EOK75_18475
PPRU: FDP22_06930
PALW: PSAL_035970
PSHQ: F3W81_11310
FAP: GR316_01445
SPHF: DM480_04795
SPZR: G5C33_02525
ROS: CTJ15_00335
RMUC: FOB66_02280
SHUM: STHU_34000
FER: FNB15_12025
SACG: FDZ84_24965
 » show all
Reference
1  [PMID:24450804]
  Authors
Bouvier JT, Groninger-Poe FP, Vetting M, Almo SC, Gerlt JA
  Title
Galactaro delta-lactone isomerase: lactone isomerization by a member of the amidohydrolase superfamily.
  Journal
Biochemistry 53:614-6 (2014)
DOI:10.1021/bi5000492
  Sequence
[atu:Atu3138]
Other DBs
ExplorEnz - The Enzyme Database: 5.4.1.4
IUBMB Enzyme Nomenclature: 5.4.1.4
ExPASy - ENZYME nomenclature database: 5.4.1.4
BRENDA, the Enzyme Database: 5.4.1.4
LinkDB

DBGET integrated database retrieval system