| Entry |
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| Name |
carboxylic acid---CoA ligase (GDP-forming);
acyl-CoA synthetase (GDP-forming);
acyl coenzyme A synthetase (guanosine diphosphate forming)
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| Class |
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
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| Sysname |
carboxylic acid:CoA ligase (GDP-forming)
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| Reaction(IUBMB) |
GTP + a carboxylate + CoA = GDP + phosphate + acyl-CoA [RN: R00394]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| History |
EC 6.2.1.10 created 1972, modified 2011
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| Reference |
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| Authors |
ROSSI CR, GIBSON DM. |
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| Title |
ACTIVATION OF FATTY ACIDS BY A GUANOSINE TRIPHOSPHATE-SPECIFIC THIOKINASE FROM LIVER MITOCHONDRIA. |
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| Journal |
J Biol Chem 239:1694-9 (1964) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 6.2.1.10 |
| ExPASy - ENZYME nomenclature database: | 6.2.1.10 |
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| LinkDB |
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