KEGG   ENZYME: 6.3.4.12
Entry
EC 6.3.4.12                 Enzyme                                 
Name
glutamate---methylamine ligase;
gamma-glutamylmethylamide synthetase
Class
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
Sysname
L-glutamate:methylamine ligase (ADP-forming)
Reaction(IUBMB)
ATP + L-glutamate + methylamine = ADP + phosphate + N5-methyl-L-glutamine [RN:R01585]
Reaction(KEGG)
R01585
Substrate
ATP [CPD:C00002];
L-glutamate [CPD:C00025];
methylamine [CPD:C00218]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
N5-methyl-L-glutamine [CPD:C03153]
History
EC 6.3.4.12 created 1972
Orthology
K01949  glutamate---methylamine ligase
Genes
GAIIMCC3135_28060(glnT)
TSNW908_01950
THINCRN91_08145(glnT)
MLNA9174_29115
MCIMesci_5156
MOPMesop_5739
MAMMesau_05234
MAMOA6B35_11075
MESWA9K65_028265
MESMEJ066_15675(glnT)
MESPC1M53_18730(glnT)
MHUAMCHK_0827(glnT)
MJREB229_29695(glnT)
MERDEB233_25740(glnT)
AAKAA2016_5807
AMIHCO731_05434(glnT)
PHTBLM14_24665
RPODE0E05_05945(glnT)
SMKSinme_3421
SMQSinmeB_3196
SMXSM11_chr3561(glnT)
SMIBN406_03224(glnT)
SMEGC770_GR4Chr0097
SMELSM2011_c02613(glnT)
SMERDU99_00490
SMDSmed_3294 Smed_6005
RHINGR_c14410(glnT)
SFHSFHH103_06333(glnT)
SIXBSY16_5797(glnT)
SAMESAMCFNEI73_pC1024
EAKEKH55_4303
ARAArad_8367(glnT)
AGRAGROH133_12302
ATFAch5_36150(glnA)
AVIAvi_5752(glnA)
AGCBSY240_3620(glnT)
AROB0909_19475(glnT)
RECRHECIAT_PA0000334(glnT)
RELREMIM1_PD00440(glnT)
REPIE4803_PA00370(glnT)
REIIE4771_PC00383(glnT)
RLTRleg2_5641
RLGRleg_6578
RLBRLEG3_05400
RLURLEG12_01965
RTRRTCIAT899_PC09295(glnT)
RHLLPU83_pLPU83c0694(glnT)
RGARGR602_PC01860(glnT)
RHNAMJ98_PD00425(glnT)
RPHAAMC79_PB00339(glnT)
RHXAMK02_PE00432(glnT)
RHKKim5_PB00401(glnT)
REZAMJ99_PC00426(glnT)
RJGCCGE525_22845(glnT)
RHRCKA34_31840(glnT)
RIIFFM53_030605(glnT)
RHIDFFM81_029950(glnT)
RLNJ0663_26870(glnT)
RBANJ2J98_25880(glnT)
RRGJ3P73_30920(glnT)
RLSHB780_09410(glnT)
SOJK6301_16505(glnT)
PDESFE840_000855(glnT)
BRABRADO5882(glnA)
BBTBBta_1945(glnA)
RPBRPB_1135
TRBHB776_20420(glnT)
BVVBHK69_09835
XAUXaut_4698
XDIEZH22_24765(glnT)
AZCAZC_1499
SNOSnov_0455
STARG3545_13135(glnT)
LNEFZC33_23790(glnT)
ANCGBB76_17685(glnT)
APRAG3A50_15290(glnT)
APOLK9D25_00540(glnT)
MEAMex_1p1553
MDIMETDI2327
MEXMext_1659
MCHMchl_1941
MPOMpop_1572
MZAB2G69_15955
MRDMrad2831_4807
METAY590_07820
MAQUMaq22A_c07630(glnA)
METDC0214_09530(glnT) C0214_27320(glnT)
METXA3862_04395
METSDK389_06155(glnT)
MMESMMSR116_29790(glnT)
MINDmvi_52000(glnT)
MOGMMB17_10265(glnT)
MSLMsil_2635
MTUNMTUNDRAET4_2822(glnT) MTUNDRAET4_3084
MLGCWB41_02760(glnT) CWB41_16065(glnT)
BBARRHAL1_02575(glnT)
HDNHden_0515
HDTHYPDE_25078
HMCHYPMC_4366(gmas)
HNIW911_11235
FILBN1229_v1_1169(glnT)
FIYBN1229_v1_1168(glnT)
MCGGL4_0799
METGHT051_11880(glnT)
CMETK6K41_10835(glnT)
PLEOOHA_1_03153(glnT)
HDIHDIA_3398(glnT)
MEYTM49_12285
AUZSa4125_08460
NOHG5V57_07095(glnT)
TSOIZ6_30310
LIZLGH83_08105(glnT)
SILSPO1573(glnT)
RDERD1_4250(glnT)
RLIRLO149_c005820(glnT)
RPONG3256_12400(glnT)
DSHDshi_1867(glnT)
OAROA238_c26820
LMDMETH_18430
LEJETW24_17950(glnT)
LAQUR2C4_19755(glnT)
REDroselon_03567
CIDP73_0133
CEHCEW89_17265(glnT)
MALGMALG_00923
YANAYJ57_19000
TPROGa0080559_TMP4880 Ga0080559_TMP4892
PABYGa0080574_TMP1115 Ga0080574_TMP4713
SULZC1J03_14650(glnT)
SULIC1J05_06630(glnT)
SPSESULPSESMR1_03830(glnT)
RMMROSMUCSMR3_00030(glnT)
ROKRAK1035_2880
RIDRIdsm_02435(glnT)
ROMEI983_08250(glnT)
ROHFIU89_08615(glnT) FIU89_17915(glnA3)
MALUKU6B_39960
PALXGQA70_20895(glnT) GQA70_23260(glnT)
RHPLPB142_05665
PAMIJCM7686_pAMI6p105
PYEA6J80_01560(glnT)
PZHCX676_01700(glnT)
PAMNpAMV1p0109(gmaS)
PTPRCA23_c23640(glnA3)
RHCRGUI_3209
DAAAKL17_0252
RBGBG454_15455(glnT)
GEHHYN69_07415(glnT)
GFUKM031_03470(glnT)
TAWEI545_08515(glnT)
PPRUFDP22_15455(glnT)
PAEDG5B38_09610(glnT)
PAMOBAR1_12125(glnT)
FAPGR316_12280(glnT)
FAQG5B39_16775(glnT)
RDICMV14_00745(glnT)
SSANNX02_15580
GTIFXF46_11725(glnT)
GBEGbCGDNIH1_2110
GBHGbCGDNIH2_2110
GBCGbCGDNIH3_2110
GBSGbCGDNIH4_2110
GXLH845_1584 H845_92
KEUS101446_00798(glnA)
KSCCD178_01529(glnT)
AACEA0U92_02370
ACEKFLP30_07220(glnT)
RAPRHOA_2529(glnT)
SHUMSTHU_53950(glnT)
SVCSTVA_53790(glnT)
STELSTAQ_48960
AZLAZL_a09540(glnA)
RPMRSPPHO_02176(glnA1)
HTQFRZ44_30250
HADHFRZ61_17270
TIIDY252_08035(glnT)
PUBSAR11_1316(glnT)
PEGE5R92_06670(glnT)
APCHIMB59_00013170
APMHIMB5_00009560
APBSAR116_1707
FALFRAAL1887(glnIII)
SYUM744_04820
CYBCYB_1005(glnA-1)
SYNESyn6312_3383
SYNPSyn7502_02094
SYNCCB0101_01845(glnT)
DSLDacsa_3567
CGCCyagr_1005
CYICBM981_0307(glnT)
CMPCha6605_0263
LENLEP3755_41240
LETO77CONTIG1_00575(glnT_1)
LBOLBWT_8910
HHGXM38_027690(glnA_1)
PSERABRG53_0397(glnA)
THEUHPC62_14825(glnT)
GLPGlo7428_3065
ENNFRE64_06535(glnT)
CYNCyan7425_0282
PLSVT03_09265(glnT)
SOHD1869_05950(glnT)
 » show all
Reference
1  [PMID:5800436]
  Authors
Kung HF, Wagner C.
  Title
Gamma-glutamylmethylamide. A new intermediate in the metabolism of methylamine.
  Journal
J Biol Chem 244:4136-40 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 6.3.4.12
IUBMB Enzyme Nomenclature: 6.3.4.12
ExPASy - ENZYME nomenclature database: 6.3.4.12
BRENDA, the Enzyme Database: 6.3.4.12
CAS: 37318-69-7
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