KEGG   COMPOUND: C13729
Entry
C13729                      Compound                               

Name
Pinacidil
Formula
C13H19N5. H2O
Exact mass
263.1746
Mol weight
263.3387
Structure
Remark
Same as: D05482
Pathway
map07232  Potassium channel blocking and opening drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C02 ANTIHYPERTENSIVES
   C02D ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON
    C02DG Guanidine derivatives
     C02DG01 Pinacidil
      D05482  Pinacidil (USAN)
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC subfamily
    ABCC8(SUR1)/KCNJ11(KIR6.2)
     D05482  Pinacidil (USAN)
    ABCC9(SUR2)/KCNJ11(KIR6.2)
     D05482  Pinacidil (USAN)
Other DBs
CAS: 85371-64-8
PubChem: 586318
ChEBI: 34923
ChEMBL: CHEMBL1200338
NIKKAJI: J2.194.149B J386.145G
LinkDB
KCF data

ATOM        19
            1   C8y C    20.7002  -18.7440
            2   N2b N    21.9108  -18.0431
            3   C2c C    23.1215  -18.7440
            4   N1b N    24.3321  -18.0431
            5   C1c C    25.5427  -18.7440
            6   C1d C    26.7532  -18.0431
            7   C8x C    19.4879  -18.0460
            8   C8x C    18.2772  -18.7469
            9   N5x N    18.2789  -20.1458
            10  C8x C    19.4913  -20.8438
            11  C8x C    20.7019  -20.1429
            12  N1b N    23.1215  -20.1458
            13  C1a C    25.5427  -20.1458
            14  C1a C    26.0453  -16.8253
            15  C1a C    27.4470  -19.2537
            16  C1a C    27.9729  -17.3522
            17  C3b C    21.9037  -20.8395
            18  N3a N    20.6861  -21.5335
            19  O0  O    32.1460  -19.4520
BOND        18
            1     7   8 1
            2     8   9 2
            3     9  10 1
            4    10  11 2
            5    11   1 1
            6     3  12 1
            7     5   6 1
            8     5  13 1
            9     2   3 2
            10    6  14 1
            11    6  15 1
            12    3   4 1
            13    6  16 1
            14    1   2 1
            15   12  17 1
            16    4   5 1
            17   17  18 3
            18    1   7 2

» Japanese version

KEGG   DRUG: Pinacidil
Entry
D05482                      Drug                                   

Name
Pinacidil (USAN);
Pinacidil hydrate;
Pindac (TN)
Formula
C13H19N5. H2O
Exact mass
263.1746
Mol weight
263.3387
Structure
Simcomp
Class
Cardiovascular agent
 DG01583  ATP-sensitive potassium channel opener
Remark
Same as: C13729
ATC code: C02DG01
Efficacy
Antihypertensive, ATP-sensitive potassium channel opener
Comment
Guanidine derivative
Target
ABCC8(SUR1)/KCNJ11(KIR6.2) [HSA:6833 3767] [KO:K05032 K05004]
ABCC9(SUR2)/KCNJ11(KIR6.2) [HSA:10060 3767] [KO:K05033 K05004]
  Pathway
hsa02010  ABC transporters
Interaction
Structure map
map07232  Potassium channel blocking and opening drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C02 ANTIHYPERTENSIVES
   C02D ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON
    C02DG Guanidine derivatives
     C02DG01 Pinacidil
      D05482  Pinacidil (USAN)
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC subfamily
    ABCC8(SUR1)/KCNJ11(KIR6.2)
     D05482  Pinacidil (USAN)
    ABCC9(SUR2)/KCNJ11(KIR6.2)
     D05482  Pinacidil (USAN)
Other DBs
CAS: 85371-64-8
PubChem: 47207151
ChEBI: 34923
ChEMBL: CHEMBL1200338
LigandBox: D05482
NIKKAJI: J2.194.149B J386.145G
LinkDB
KCF data

ATOM        19
            1   C8y C    20.7002  -18.7440
            2   N2b N    21.9108  -18.0431
            3   C2c C    23.1215  -18.7440
            4   N1b N    24.3321  -18.0431
            5   C1c C    25.5427  -18.7440
            6   C1d C    26.7532  -18.0431
            7   C8x C    19.4879  -18.0460
            8   C8x C    18.2772  -18.7469
            9   N5x N    18.2789  -20.1458
            10  C8x C    19.4913  -20.8438
            11  C8x C    20.7019  -20.1429
            12  N1b N    23.1215  -20.1458
            13  C1a C    25.5427  -20.1458
            14  C1a C    26.0453  -16.8253
            15  C1a C    27.4470  -19.2537
            16  C1a C    27.9729  -17.3522
            17  C3b C    21.9037  -20.8395
            18  N3a N    20.6861  -21.5335
            19  O0  O    32.2860  -19.4520
BOND        18
            1     7   8 1
            2     8   9 2
            3     9  10 1
            4    10  11 2
            5    11   1 1
            6     3  12 1
            7     5   6 1
            8     5  13 1
            9     2   3 2
            10    6  14 1
            11    6  15 1
            12    3   4 1
            13    6  16 1
            14    1   2 1
            15   12  17 1
            16    4   5 1
            17   17  18 3
            18    1   7 2

» Japanese version   » Back

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