KEGG   DRUG: Triamcinolone
Entry
D00385                      Drug                                   
Name
Triamcinolone (JP18/USP/INN);
Aristocort (TN);
Kenacort (TN)
Formula
C21H27FO6
Exact mass
394.1792
Mol weight
394.43
Structure
Simcomp
Class
Anti-inflammatory
 DG01955  Corticosteroid
  DG02068  Glucocorticoid
Dermatological agent
 DG03243  Atopic dermatitis agent
Remark
Therapeutic category: 2454
ATC code: A01AC01 C05AA12 D07AB09 D07XB02 H02AB08 R01AD11 R03BA06 S01BA05
Chemical structure group: DG00010
Product (DG00010): D00385<JP> D00983<JP/US>
Efficacy
Antiasthmatic, Anti-inflammatory, Antirheumatic, Glucocorticoid receptor agonist
Target
NR3C1 (GR) [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07225  Glucocorticoid and mineralocorticoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AC Corticosteroids for local oral treatment
     A01AC01 Triamcinolone
      D00385  Triamcinolone (JP18/USP/INN) <JP>
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA12 Triamcinolone
      D00385  Triamcinolone (JP18/USP/INN) <JP>
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AB Corticosteroids, moderately potent (group II)
     D07AB09 Triamcinolone
      D00385  Triamcinolone (JP18/USP/INN) <JP>
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XB Corticosteroids, moderately potent, other combinations
     D07XB02 Triamcinolone
      D00385  Triamcinolone (JP18/USP/INN) <JP>
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB08 Triamcinolone
      D00385  Triamcinolone (JP18/USP/INN) <JP>
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD11 Triamcinolone
      D00385  Triamcinolone (JP18/USP/INN) <JP>
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BA Glucocorticoids
     R03BA06 Triamcinolone
      D00385  Triamcinolone (JP18/USP/INN) <JP>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA05 Triamcinolone
      D00385  Triamcinolone (JP18/USP/INN) <JP>
USP drug classification [BR:br08302]
 Dental and Oral Agents
  Triamcinolone
   D00385  Triamcinolone (JP18/USP/INN)
 Hormonal Agents, Stimulant/Replacement/Modifying (Adrenal)
  Triamcinolone
   D00385  Triamcinolone (JP18/USP/INN)
 Respiratory Tract/Pulmonary Agents
  Anti-inflammatories, Inhaled Corticosteroids
   Triamcinolone
    D00385  Triamcinolone (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   245  Adrenal hormone preparations
    2454  Fluorinated adrenocorticotropic hormones
     D00385  Triamcinolone (JP18/USP/INN)
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01955  Corticosteroid
   DG02068  Glucocorticoid
    DG00010  Triamcinolone
     D00385  Triamcinolone
 Dermatological agent
  DG03243  Atopic dermatitis agent
   D00385  Triamcinolone
Drug classes [BR:br08332]
 Anti-inflammatory
  DG01955  Corticosteroid
   D00385  Triamcinolone
 Dermatological agent
  DG03243  Atopic dermatitis agent
   D00385  Triamcinolone
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D00385  Triamcinolone (JP18/USP/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00385  Triamcinolone
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01955  Corticosteroid
   DG02068  Glucocorticoid
    DG00010  Triamcinolone
Other DBs
CAS: 124-94-7
PubChem: 7847451
ChEBI: 9667
LigandBox: D00385
NIKKAJI: J2.508I
LinkDB
KCF data

ATOM        28
            1   C2x C    14.0000  -26.6700
            2   C5x C    14.0000  -28.0700
            3   C2x C    15.2124  -28.7700
            4   C2y C    16.4249  -28.0700
            5   C1z C    16.4249  -26.6700
            6   C2x C    15.2124  -25.9700
            7   C1x C    17.6373  -28.7700
            8   C1x C    18.8497  -28.0700
            9   C1y C    18.8497  -26.6700
            10  C1z C    17.6373  -25.9700
            11  C1y C    20.0622  -25.9700
            12  C1z C    20.0622  -24.5700
            13  C1x C    18.8497  -23.8700
            14  C1y C    17.6373  -24.5700
            15  C1x C    22.4870  -25.9700
            16  C1y C    22.4870  -24.5700
            17  C1z C    21.2746  -23.8700
            18  O5x O    12.7876  -28.7700
            19  C1a C    16.4249  -25.2700
            20  X   F    17.6373  -27.3700
            21  O1a O    16.4269  -23.8712
            22  C1a C    20.0622  -23.1700
            23  C5a C    21.2746  -22.1900
            24  O1a O    22.6970  -22.9600
            25  O1a O    23.6866  -23.8773
            26  O5a O    22.4911  -21.4877
            27  C1b C    20.0662  -21.4923
            28  O1a O    18.8727  -22.1816
BOND        31
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   11  15 1
            18   15  16 1
            19   16  17 1
            20   12  17 1
            21    2  18 2
            22    5  19 1 #Up
            23   10  20 1 #Down
            24   14  21 1 #Up
            25   12  22 1 #Up
            26   17  23 1 #Up
            27   17  24 1 #Down
            28   16  25 1 #Down
            29   23  26 2
            30   23  27 1
            31   27  28 1

» Japanese version   » Back

KEGG   DRUG: Triamcinolone acetonide
Entry
D00983                      Drug                                   
Name
Triamcinolone acetonide (JP18/USP);
Azmacort (TN);
Kenalog (TN);
Nasacort (TN)
Product
KENALOG (Sun Pharmaceutical Industries), KENALOG-10 (A-S Medication Solutions), KENALOG-10 (E.R. Squibb & Sons), KENALOG-40 (A-S Medication Solutions), KENALOG-40 (A-S Medication Solutions), KENALOG-40 (Asclemed USA), KENALOG-40 (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (E.R. Squibb & Sons), TRIESENCE (Alcon Laboratories), XIPERE (Bausch & Lomb Incorporated), XIPERE (Clearside Biomedical), ZILRETTA (Pacira Pharmaceuticals)
  Generic
KOURZEQ (MidAmerica Pharmaceuticals), ORALONE (Taro Pharmaceuticals U.S.A.), SCARZEN (Village Pharma LLC), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (A-S Medication Solutions), TRIAMCINOLONE ACETONIDE (Advanced Rx Pharmacy of Tennessee), TRIAMCINOLONE ACETONIDE (Amneal Pharmaceuticals LLC), TRIAMCINOLONE ACETONIDE (Amneal Pharmaceuticals LLC), TRIAMCINOLONE ACETONIDE (Amneal Pharmaceuticals LLC), TRIAMCINOLONE ACETONIDE (Ascend Laboratories), TRIAMCINOLONE ACETONIDE (Asclemed USA), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Bryant Ranch Prepack), TRIAMCINOLONE ACETONIDE (Burel Pharmaceuticals), TRIAMCINOLONE ACETONIDE (CMP Pharma), TRIAMCINOLONE ACETONIDE (Cintex Services), TRIAMCINOLONE ACETONIDE (Cosette Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Cosette Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Cosette Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Cosette Pharmaceuticals), TRIAMCINOLONE ACETONIDE (DIRECTRX), TRIAMCINOLONE ACETONIDE (Direct Rx), TRIAMCINOLONE ACETONIDE (Direct_Rx), TRIAMCINOLONE ACETONIDE (Direct_rx), TRIAMCINOLONE ACETONIDE (E. Fougera & Co. a division of Fougera Pharmaceuticals), TRIAMCINOLONE ACETONIDE (E. Fougera & Co. a division of Fougera Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Encube Ethicals Private Limited), TRIAMCINOLONE ACETONIDE (Encube Ethicals Private Limited), TRIAMCINOLONE ACETONIDE (Encube Ethicals Private Limited), TRIAMCINOLONE ACETONIDE (Eugia US LLC), TRIAMCINOLONE ACETONIDE (Glenmark Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Glenmark Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Lake Erie Medical DBA Quality Care Products LLC), TRIAMCINOLONE ACETONIDE (Long Grove Pharmaceuticals), TRIAMCINOLONE ACETONIDE (MICRO LABS LIMITED), TRIAMCINOLONE ACETONIDE (Macleods Pharmaceuticals Limited), TRIAMCINOLONE ACETONIDE (Macleods Pharmaceuticals Limited), TRIAMCINOLONE ACETONIDE (Macleods Pharmaceuticals Limited), TRIAMCINOLONE ACETONIDE (Mayne Pharma), TRIAMCINOLONE ACETONIDE (Mylan Institutional LLC), TRIAMCINOLONE ACETONIDE (NorthStar Rx LLC), TRIAMCINOLONE ACETONIDE (NorthStar RxLLC), TRIAMCINOLONE ACETONIDE (NorthStar RxLLC), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (NuCare Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Padagis Israel Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Padagis Israel Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Padagis Israel Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Padagis Israel Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (Proficient Rx LP), TRIAMCINOLONE ACETONIDE (QUAGEN PHARMACEUTICALS LLC), TRIAMCINOLONE ACETONIDE (QUAGEN PHARMACEUTICALS LLC), TRIAMCINOLONE ACETONIDE (REMEDYREPACK), TRIAMCINOLONE ACETONIDE (REMEDYREPACK), TRIAMCINOLONE ACETONIDE (REMEDYREPACK), TRIAMCINOLONE ACETONIDE (REMEDYREPACK), TRIAMCINOLONE ACETONIDE (REMEDYREPACK), TRIAMCINOLONE ACETONIDE (REMEDYREPACK), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RPK Pharmaceuticals), TRIAMCINOLONE ACETONIDE (RedPharm Drug), TRIAMCINOLONE ACETONIDE (RedPharm Drug), TRIAMCINOLONE ACETONIDE (RedPharm Drug), TRIAMCINOLONE ACETONIDE (RedPharm Drug), TRIAMCINOLONE ACETONIDE (RedPharm Drug), TRIAMCINOLONE ACETONIDE (RedPharm Drug), TRIAMCINOLONE ACETONIDE (Rising Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Saptalis Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Strides Pharma Science Limited), TRIAMCINOLONE ACETONIDE (Taro Pharmaceuticals U.S.A.), TRIAMCINOLONE ACETONIDE (Taro Pharmaceuticals U.S.A.), TRIAMCINOLONE ACETONIDE (Taro Pharmaceuticals U.S.A.), TRIAMCINOLONE ACETONIDE (Teva Parenteral Medicines), TRIAMCINOLONE ACETONIDE (TruPharma), TRIAMCINOLONE ACETONIDE (medsource pharmaceuticals), TRIDERM (Crown Laboratories)
Formula
C24H31FO6
Exact mass
434.2105
Mol weight
434.50
Structure
Simcomp
Class
Anti-inflammatory
 DG01955  Corticosteroid
  DG02068  Glucocorticoid
Dermatological agent
 DG03243  Atopic dermatitis agent
Remark
Same as: C08183
Therapeutic category: 1319 2399 2454 2646
ATC code: A01AC01 C05AA12 D07AB09 D07XB02 H02AB08 R01AD11 R03BA06 S01BA05
Chemical structure group: DG00010
Product (DG00010): D00385<JP> D00983<JP/US>
Product (mixture): D10299<US>
Efficacy
Antiasthmatic, Anti-inflammatory, Antirheumatic, Glucocorticoid receptor agonist
  Disease
Asthma [DS:H00079]
Atopic dermatitis [DS:H01358]
Contact dermatitis [DS:H01357]
Perennial or seasonal allergic rhinitis [DS:H01360]
Bullous dermatitis herpetiformis [DS:H01362]
Mycosis fungoides [DS:H01463]
Pemphigus [DS:H01648]
Erythema multiforme [DS:H01695]
Stevens-Johnson syndrome [DS:H01694]
Primary adrenocortical insufficiency [DS:H01598]
Congenital adrenal hyperplasia [DS:H00216]
Ulcerative colitis [DS:H01466]
Acquired (autoimmune) hemolytic anemia [DS:H01585]
Diamond-Blackfan anemia [DS:H00237]
Pure red cell aplasia [DS:H01586]
Thrombocytopenia [DS:H00978]
Multiple sclerosis [DS:H01490]
Temporal arteritis [DS:H01698]
Nephrotic syndrome [DS:H01657]
Pulmonary tuberculosis [DS:H00342]
Ankylosing spondylitis [DS:H01674]
Psoriatic arthritis [DS:H01507]
Rheumatoid arthritis [DS:H00630]
Juvenile rheumatoid arthritis [DS:H01672]
Dermatomyositis and polymyositis [DS:H01604]
Systemic lupus erythematosus [DS:H00080]
Target
NR3C1 (GR) [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07225  Glucocorticoid and mineralocorticoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AC Corticosteroids for local oral treatment
     A01AC01 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA12 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AB Corticosteroids, moderately potent (group II)
     D07AB09 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XB Corticosteroids, moderately potent, other combinations
     D07XB02 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB08 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD11 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BA Glucocorticoids
     R03BA06 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA05 Triamcinolone
      D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
 Dental and Oral Agents
  Triamcinolone
   D00983  Triamcinolone acetonide (JP18/USP)
 Dermatological Agents
  Dermatitis and Pruitus Agents
   Glucocorticoids, Medium Potency
    Triamcinolone
     D00983  Triamcinolone acetonide (JP18/USP)
   Glucocorticoids, High Potency
    Triamcinolone
     D00983  Triamcinolone acetonide (JP18/USP)
 Hormonal Agents, Stimulant/Replacement/Modifying (Adrenal)
  Triamcinolone
   D00983  Triamcinolone acetonide (JP18/USP)
 Inflammatory Bowel Disease Agents
  Glucocorticoids
   Triamcinolone
    D00983  Triamcinolone acetonide (JP18/USP)
 Ophthalmic Agents
  Ophthalmic Anti-inflammatories
   Glucocorticoids, Ophthalmic
    Triamcinolone
     D00983  Triamcinolone acetonide (JP18/USP)
 Respiratory Tract/Pulmonary Agents
  Anti-inflammatories, Inhaled Corticosteroids
   Triamcinolone
    D00983  Triamcinolone acetonide (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1319  Others
     D00983  Triamcinolone acetonide (JP18/USP)
 2  Agents affecting individual organs
  23  Digestive organ agents
   239  Miscellaneous
    2399  Others
     D00983  Triamcinolone acetonide (JP18/USP)
  24  Hormones
   245  Adrenal hormone preparations
    2454  Fluorinated adrenocorticotropic hormones
     D00983  Triamcinolone acetonide (JP18/USP)
  26  Epidermides
   264  Analgesics, anti-itchings, astringents, anti-inflammatory agents
    2646  Adrenocorticotropic hormones
     D00983  Triamcinolone acetonide (JP18/USP)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for dental and stomatological use
  74 Stomatitis remedies
   D00983  Triamcinolone acetonide (JP18/USP)
Risk category of Japanese OTC drugs [BR:br08312]
 Designated second-class OTC drugs
  Inorganic and organic chemicals
   Triamcinolone acetonide
    D00983  Triamcinolone acetonide (JP18/USP)
 Second-class OTC drugs
  Inorganic and organic chemicals
   Triamcinolone acetonide
    D00983  Triamcinolone acetonide (JP18/USP)
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01955  Corticosteroid
   DG02068  Glucocorticoid
    DG00010  Triamcinolone
     D00983  Triamcinolone acetonide
 Dermatological agent
  DG03243  Atopic dermatitis agent
   D00983  Triamcinolone acetonide
Drug classes [BR:br08332]
 Anti-inflammatory
  DG01955  Corticosteroid
   D00983  Triamcinolone acetonide
 Dermatological agent
  DG03243  Atopic dermatitis agent
   D00983  Triamcinolone acetonide
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D00983  Triamcinolone acetonide (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00983  Triamcinolone acetonide
Topical steroids potency [br08317.html]
 Classification in the USA
  D00983
 Classification in Japan
  D00983
Rx-to-OTC switch list in the USA [br08315.html]
 D00983
Rx-to-OTC switch list in Japan [br08314.html]
 D00983
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01955  Corticosteroid
   DG02068  Glucocorticoid
    DG00010  Triamcinolone
Other DBs
CAS: 76-25-5
PubChem: 7848046
ChEBI: 71418
PDB-CCD: 1TA[PDBj]
LigandBox: D00983
NIKKAJI: J55.714E
LinkDB
KCF data

ATOM        31
            1   C2x C    18.6900  -28.5600
            2   C5x C    18.6900  -29.8900
            3   C2x C    19.8800  -30.5900
            4   C2y C    21.0700  -29.8900
            5   C1z C    21.0700  -28.5600
            6   C2x C    19.8800  -27.8600
            7   C1x C    22.2600  -30.5900
            8   C1x C    23.4500  -29.8900
            9   C1y C    23.4500  -28.5600
            10  C1z C    22.2600  -27.8600
            11  C1y C    24.5700  -27.8600
            12  C1z C    24.5700  -26.5300
            13  C1x C    23.4500  -25.8300
            14  C1y C    22.2600  -26.5300
            15  C1x C    26.9500  -27.8600
            16  C1y C    26.9500  -26.5300
            17  C1z C    25.7600  -25.8300
            18  O5x O    17.5700  -30.5900
            19  C1a C    21.0700  -27.1600
            20  X   F    22.2600  -29.1900
            21  O1a O    21.0700  -25.8300
            22  C1a C    24.5700  -25.1300
            23  C5a C    25.7600  -24.2200
            24  O2x O    27.1600  -24.9200
            25  O5a O    26.9500  -23.5200
            26  C1b C    24.5700  -23.5200
            27  O1a O    23.4500  -24.2200
            28  O2x O    28.3500  -26.5300
            29  C1z C    28.5600  -24.9200
            30  C1a C    29.9600  -24.9200
            31  C1a C    28.5600  -23.5200
BOND        35
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   11  15 1
            18   15  16 1
            19   16  17 1
            20   12  17 1
            21    2  18 2
            22    5  19 1 #Up
            23   10  20 1 #Down
            24   14  21 1 #Up
            25   12  22 1 #Up
            26   17  23 1 #Up
            27   17  24 1 #Down
            28   23  25 2
            29   23  26 1
            30   26  27 1
            31   16  28 1 #Down
            32   24  29 1
            33   29  28 1
            34   29  30 1
            35   29  31 1

» Japanese version   » Back

KEGG   DRUG: Triamcinolone diacetate
Entry
D00984                      Drug                                   
Name
Triamcinolone diacetate (JAN/USP);
Aristocort (TN)
Formula
C25H31FO8
Exact mass
478.2003
Mol weight
478.51
Structure
Simcomp
Class
Anti-inflammatory
 DG01955  Corticosteroid
  DG02068  Glucocorticoid
Remark
Same as: C08184
ATC code: A01AC01 C05AA12 D07AB09 D07XB02 H02AB08 R01AD11 R03BA06 S01BA05
Chemical structure group: DG00010
Product (DG00010): D00385<JP> D00983<JP/US>
Efficacy
Anti-inflammatory, Glucocorticoid receptor agonist
Target
NR3C1 (GR) [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07225  Glucocorticoid and mineralocorticoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AC Corticosteroids for local oral treatment
     A01AC01 Triamcinolone
      D00984  Triamcinolone diacetate (JAN/USP)
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA12 Triamcinolone
      D00984  Triamcinolone diacetate (JAN/USP)
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AB Corticosteroids, moderately potent (group II)
     D07AB09 Triamcinolone
      D00984  Triamcinolone diacetate (JAN/USP)
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XB Corticosteroids, moderately potent, other combinations
     D07XB02 Triamcinolone
      D00984  Triamcinolone diacetate (JAN/USP)
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB08 Triamcinolone
      D00984  Triamcinolone diacetate (JAN/USP)
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD11 Triamcinolone
      D00984  Triamcinolone diacetate (JAN/USP)
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BA Glucocorticoids
     R03BA06 Triamcinolone
      D00984  Triamcinolone diacetate (JAN/USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA05 Triamcinolone
      D00984  Triamcinolone diacetate (JAN/USP)
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01955  Corticosteroid
   DG02068  Glucocorticoid
    DG00010  Triamcinolone
     D00984  Triamcinolone diacetate
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D00984  Triamcinolone diacetate (JAN/USP)
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01955  Corticosteroid
   DG02068  Glucocorticoid
    DG00010  Triamcinolone
Other DBs
CAS: 67-78-7
PubChem: 7848047
ChEBI: 9669
LigandBox: D00984
NIKKAJI: J4.852F
LinkDB
KCF data

ATOM        34
            1   C2x C    18.6900  -29.1900
            2   C5x C    18.6900  -30.5200
            3   C2x C    19.8800  -31.2200
            4   C2y C    21.0700  -30.5200
            5   C1z C    21.0700  -29.1900
            6   C2x C    19.8800  -28.4900
            7   C1x C    22.2600  -31.2200
            8   C1x C    23.4500  -30.5200
            9   C1y C    23.4500  -29.1900
            10  C1z C    22.2600  -28.4900
            11  C1y C    24.5000  -28.4900
            12  C1z C    24.5000  -27.1600
            13  C1x C    23.4500  -26.4600
            14  C1y C    22.2600  -27.1600
            15  C1x C    26.8800  -28.4900
            16  C1y C    26.8800  -27.1600
            17  C1z C    25.6900  -26.4600
            18  O5x O    17.5700  -31.2200
            19  C1a C    21.0700  -27.7900
            20  X   F    22.2600  -29.8200
            21  O1a O    21.0700  -26.4600
            22  C1a C    24.5000  -25.7600
            23  C5a C    25.6900  -24.8500
            24  O1a O    27.0900  -25.5500
            25  O5a O    26.8800  -24.2200
            26  C1b C    24.5000  -24.2200
            27  O7a O    23.4500  -24.8500
            28  C7a C    22.2260  -24.1705
            29  C1a C    21.0595  -24.8703
            30  O6a O    22.2716  -22.7512
            31  O7a O    28.0953  -26.4649
            32  C7a C    29.2837  -27.1577
            33  C1a C    30.4801  -26.4735
            34  O6a O    29.2780  -28.5599
BOND        37
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   11  15 1
            18   15  16 1
            19   16  17 1
            20   12  17 1
            21    2  18 2
            22    5  19 1 #Up
            23   10  20 1 #Down
            24   14  21 1 #Up
            25   12  22 1 #Up
            26   17  23 1 #Up
            27   17  24 1 #Down
            28   23  25 2
            29   23  26 1
            30   26  27 1
            31   27  28 1
            32   28  29 1
            33   28  30 2
            34   16  31 1 #Down
            35   31  32 1
            36   32  33 1
            37   32  34 2

» Japanese version   » Back

KEGG   DRUG: Triamcinolone acetonide sodium phosphate
Entry
D06216                      Drug                                   
Name
Triamcinolone acetonide sodium phosphate (USAN)
Formula
C24H30FO9P. 2Na
Exact mass
558.1407
Mol weight
558.44
Structure
Simcomp
Class
Anti-inflammatory
 DG01955  Corticosteroid
  DG02068  Glucocorticoid
Remark
ATC code: A01AC01 C05AA12 D07AB09 D07XB02 H02AB08 R01AD11 R03BA06 S01BA05
Chemical structure group: DG00010
Product (DG00010): D00385<JP> D00983<JP/US>
Efficacy
Anti-inflammatory, Glucocorticoid receptor agonist
Target
NR3C1 (GR) [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07225  Glucocorticoid and mineralocorticoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AC Corticosteroids for local oral treatment
     A01AC01 Triamcinolone
      D06216  Triamcinolone acetonide sodium phosphate (USAN)
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA12 Triamcinolone
      D06216  Triamcinolone acetonide sodium phosphate (USAN)
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AB Corticosteroids, moderately potent (group II)
     D07AB09 Triamcinolone
      D06216  Triamcinolone acetonide sodium phosphate (USAN)
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XB Corticosteroids, moderately potent, other combinations
     D07XB02 Triamcinolone
      D06216  Triamcinolone acetonide sodium phosphate (USAN)
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB08 Triamcinolone
      D06216  Triamcinolone acetonide sodium phosphate (USAN)
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD11 Triamcinolone
      D06216  Triamcinolone acetonide sodium phosphate (USAN)
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BA Glucocorticoids
     R03BA06 Triamcinolone
      D06216  Triamcinolone acetonide sodium phosphate (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA05 Triamcinolone
      D06216  Triamcinolone acetonide sodium phosphate (USAN)
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01955  Corticosteroid
   DG02068  Glucocorticoid
    DG00010  Triamcinolone
     D06216  Triamcinolone acetonide sodium phosphate
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D06216  Triamcinolone acetonide sodium phosphate (USAN)
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01955  Corticosteroid
   DG02068  Glucocorticoid
    DG00010  Triamcinolone
Other DBs
CAS: 1997-15-5
PubChem: 47207874
LigandBox: D06216
NIKKAJI: J7.844A
LinkDB
KCF data

ATOM        37
            1   Z   Na   24.3661  -22.1928 #+
            2   Z   Na   18.6951  -22.6834 #+
            3   C2x C    18.8300  -28.6300
            4   C5x C    18.8300  -29.9600
            5   C2x C    20.0200  -30.6600
            6   C2y C    21.1400  -29.9600
            7   C1z C    21.1400  -28.6300
            8   C2x C    20.0200  -28.0000
            9   C1x C    22.3300  -30.6600
            10  C1x C    23.5200  -29.9600
            11  C1y C    23.5200  -28.6300
            12  C1z C    22.3300  -28.0000
            13  C1y C    24.5700  -28.0000
            14  C1z C    24.5700  -26.6700
            15  C1x C    23.5200  -25.9700
            16  C1y C    22.3300  -26.6700
            17  C1x C    26.8800  -28.0000
            18  C1y C    26.8800  -26.6700
            19  C1z C    25.6900  -25.9700
            20  O5x O    17.7100  -30.6600
            21  C1a C    21.1400  -27.3000
            22  X   F    22.3300  -29.2600
            23  O1a O    21.1400  -25.9700
            24  C1a C    24.5700  -25.2700
            25  C5a C    25.6900  -24.1500
            26  O2x O    27.0900  -25.0600
            27  O2x O    28.2800  -26.6700
            28  C1z C    28.4900  -25.0600
            29  C1a C    29.8200  -25.0600
            30  C1a C    28.4900  -23.8000
            31  O5a O    26.8800  -23.4500
            32  C1b C    24.5000  -23.4500
            33  O2b O    23.3100  -24.1500
            34  P1b P    22.0919  -23.4599
            35  O1c O    20.8795  -22.7599 #-
            36  O1c O    22.7919  -22.2474 #-
            37  O1c O    21.3219  -24.7423
BOND        39
            1     3   4 1
            2     4   5 1
            3     5   6 2
            4     6   7 1
            5     7   8 1
            6     3   8 2
            7     6   9 1
            8     9  10 1
            9    10  11 1
            10   11  12 1
            11    7  12 1
            12   11  13 1
            13   13  14 1
            14   14  15 1
            15   15  16 1
            16   12  16 1
            17   13  17 1
            18   17  18 1
            19   18  19 1
            20   14  19 1
            21    4  20 2
            22    7  21 1 #Up
            23   12  22 1 #Down
            24   16  23 1 #Up
            25   14  24 1 #Up
            26   19  25 1 #Up
            27   19  26 1 #Down
            28   18  27 1 #Down
            29   26  28 1
            30   28  27 1
            31   28  29 1
            32   28  30 1
            33   25  31 2
            34   25  32 1
            35   32  33 1
            36   33  34 1
            37   34  35 1
            38   34  36 1
            39   34  37 2

» Japanese version   » Back

DBGET integrated database retrieval system