| Entry |
|
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| Name |
Pergolide mesylate (USP);
Pergolide mesilate (JAN);
Permax (TN) |
|---|
| Formula |
C19H26N2S. CH4SO3
|
|---|
| Exact mass |
410.1698
|
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| Mol weight |
410.60
|
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
| Therapeutic category: | 1169 |
| Product (DG00861): | D00502<JP> |
|
|---|
| Efficacy |
Antiparkinsonian, Dopamine receptor agonist |
|---|
| Comment |
Ergot alkaloid derivative
|
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| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04B DOPAMINERGIC AGENTS
N04BC Dopamine agonists
N04BC02 Pergolide
D00502 Pergolide mesylate (USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
116 Antiparkinsonian agents
1169 Others
D00502 Pergolide mesylate (USP); Pergolide mesilate (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01472 Dopamine agonist
DG00861 Pergolide
D00502 Pergolide mesylate
DG01964 Ergot alkaloid
DG00861 Pergolide
D00502 Pergolide mesylate
DG01967 Antiparkinson agent
DG00861 Pergolide
D00502 Pergolide mesylate
Drug classes [BR:br08332]
Neuropsychiatric agent
DG01967 Antiparkinson agent
D00502 Pergolide mesylate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD1
D00502 Pergolide mesylate (USP) <JP>
DRD2
D00502 Pergolide mesylate (USP) <JP>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01472 Dopamine agonist
DG00861 Pergolide
DG01964 Ergot alkaloid
DG00861 Pergolide
DG01967 Antiparkinson agent
DG00861 Pergolide
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 27
1 C8y C 18.8582 -21.8811
2 C8y C 18.8640 -20.5217
3 C8y C 20.0310 -22.5639
4 C8y C 17.6679 -22.5579
5 C1y C 20.0368 -19.8390
6 C8x C 17.6855 -19.8156
7 C1x C 21.2097 -21.8870
8 C8x C 20.0310 -23.9233
9 N4x N 17.6679 -23.9233
10 C8x C 16.4893 -21.8637
11 C1y C 21.2097 -20.5217
12 C1x C 20.0484 -18.4796
13 C8x C 16.4951 -20.4924
14 N1y N 22.3941 -19.8566
15 C1y C 21.2329 -17.8144
16 C1x C 22.4057 -18.4970
17 C1b C 23.5610 -20.5391
18 C1b C 21.2388 -16.4432
19 C1b C 24.7513 -19.8682
20 S2a S 22.4233 -15.7663
21 C1a C 25.9241 -20.5625
22 C1a C 22.4349 -14.4011
23 S4a S 31.2682 -20.5100
24 C1a C 29.8738 -20.4926
25 O1d O 32.6628 -20.5042
26 O1d O 31.2682 -19.1039
27 O1d O 31.2625 -21.9104
BOND 29
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 2 6 2
6 3 7 1
7 3 8 2
8 4 9 1
9 4 10 1
10 5 11 1
11 5 12 1
12 6 13 1
13 11 14 1
14 12 15 1
15 14 16 1
16 14 17 1
17 15 18 1 #Up
18 17 19 1
19 18 20 1
20 19 21 1
21 20 22 1
22 7 11 1
23 8 9 1
24 10 13 2
25 15 16 1
26 23 24 1
27 23 25 1
28 23 26 2
29 23 27 2
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