Entry |
|
Name |
Tetracaine hydrochloride (JP18/USP); Protocaine hydrochloride (TN) |
Product |
|
Formula |
C15H24N2O2. HCl
|
Exact mass |
300.1605
|
Mol weight |
300.82
|
Structure |
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Simcomp |
|
Class |
|
Remark |
Product (DG00296): | D00741<US> |
Product (mixture): | D04816<JP> |
|
Efficacy |
Anesthetic (local) |
Comment |
Ester-type
|
Target |
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Pathway |
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Interaction |
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Structure map |
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Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AD Local anesthetics
C05AD02 Tetracaine
D00741 Tetracaine hydrochloride (JP18/USP) <US>
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AB Anesthetics for topical use
D04AB06 Tetracaine
D00741 Tetracaine hydrochloride (JP18/USP) <US>
N NERVOUS SYSTEM
N01 ANESTHETICS
N01B ANESTHETICS, LOCAL
N01BA Esters of aminobenzoic acid
N01BA03 Tetracaine
D00741 Tetracaine hydrochloride (JP18/USP) <US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01H LOCAL ANESTHETICS
S01HA Local anesthetics
S01HA03 Tetracaine
D00741 Tetracaine hydrochloride (JP18/USP) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG01675 Local anesthetic
DG01674 Esterified local anesthetic
DG00296 Tetracaine
D00741 Tetracaine hydrochloride
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Sodium channels
SCN1A
D00741 Tetracaine hydrochloride (JP18/USP) <US>
SCN2A
D00741 Tetracaine hydrochloride (JP18/USP) <US>
SCN3A
D00741 Tetracaine hydrochloride (JP18/USP) <US>
SCN4A
D00741 Tetracaine hydrochloride (JP18/USP) <US>
SCN5A
D00741 Tetracaine hydrochloride (JP18/USP) <US>
SCN8A
D00741 Tetracaine hydrochloride (JP18/USP) <US>
SCN9A
D00741 Tetracaine hydrochloride (JP18/USP) <US>
SCN10A
D00741 Tetracaine hydrochloride (JP18/USP) <US>
SCN11A
D00741 Tetracaine hydrochloride (JP18/USP) <US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00741 Tetracaine hydrochloride
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG01675 Local anesthetic
DG01674 Esterified local anesthetic
DG00296 Tetracaine
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Other DBs |
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LinkDB |
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KCF data |
ATOM 20
1 C8y C 25.5966 -17.9141
2 C7a C 26.8041 -18.6141
3 C8x C 25.5966 -16.5083
4 C8x C 24.3891 -18.6141
5 O7a O 28.0117 -17.9200
6 O6a O 26.7925 -20.0199
7 C8x C 24.3891 -15.8140
8 C8x C 23.1699 -17.9141
9 C1b C 29.2249 -18.6258
10 C8y C 23.1699 -16.5083
11 C1b C 30.4384 -17.9257
12 N1b N 21.9566 -15.8140
13 N1c N 31.6517 -18.6315
14 C1b C 20.7491 -16.5083
15 C1a C 32.8649 -17.9257
16 C1a C 31.6457 -20.0315
17 C1b C 19.5356 -15.8140
18 C1b C 18.3224 -16.5083
19 C1a C 17.1090 -15.8140
20 X Cl 31.6373 -15.9623
BOND 19
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 2 6 2
6 3 7 2
7 4 8 1
8 5 9 1
9 7 10 1
10 9 11 1
11 10 12 1
12 11 13 1
13 12 14 1
14 13 15 1
15 13 16 1
16 14 17 1
17 17 18 1
18 18 19 1
19 8 10 2
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