| Entry |
|
|---|
| Name |
Benztropine mesylate (USP);
Benztropine mesilate (JAN);
Cogentin (TN) |
|---|
| Product |
|
|---|
| Generic |
BENZTROPINE MESYLATE (A-S Medication Solutions), BENZTROPINE MESYLATE (American Health Packaging), BENZTROPINE MESYLATE (Aphena Pharma Solutions - Tennessee), BENZTROPINE MESYLATE (Aphena Pharma Solutions - Tennnessee), BENZTROPINE MESYLATE (Bryant Ranch Prepack), BENZTROPINE MESYLATE (Bryant Ranch Prepack), BENZTROPINE MESYLATE (Bryant Ranch Prepack), BENZTROPINE MESYLATE (Chartwell RX), BENZTROPINE MESYLATE (Cipla USA), BENZTROPINE MESYLATE (Fresenius Kabi USA), BENZTROPINE MESYLATE (Hikma Pharmaceuticals USA), BENZTROPINE MESYLATE (Hikma Pharmaceuticals USA), BENZTROPINE MESYLATE (Leading Pharma), BENZTROPINE MESYLATE (Major Pharmaceuticals), BENZTROPINE MESYLATE (NCS HealthCare of KY), BENZTROPINE MESYLATE (NCS HealthCare of KY), BENZTROPINE MESYLATE (Navinta LLC), BENZTROPINE MESYLATE (Par Pharmaceutical), BENZTROPINE MESYLATE (Proficient Rx LP), BENZTROPINE MESYLATE (REMEDYREPACK), BENZTROPINE MESYLATE (REMEDYREPACK), BENZTROPINE MESYLATE (REMEDYREPACK), BENZTROPINE MESYLATE (REMEDYREPACK), BENZTROPINE MESYLATE (Zydus Pharmaceuticals USA) |
|---|
| Formula |
C21H25NO. CH4SO3
|
|---|
| Exact mass |
403.1817
|
|---|
| Mol weight |
403.54
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
|
|---|
| Remark |
| Product (DG00859): | D00778<US> |
|
|---|
| Efficacy |
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist |
|---|
| Disease |
|
|---|
| Comment |
Tropane derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04A ANTICHOLINERGIC AGENTS
N04AC Ethers of tropine or tropine derivatives
N04AC01 Benzatropine
D00778 Benztropine mesylate (USP) <US>
USP drug classification [BR:br08302]
Antiparkinson Agents
Anticholinergics
Benztropine
D00778 Benztropine mesylate (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00859 Benzatropine
D00778 Benztropine mesylate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D00778 Benztropine mesylate (USP) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00859 Benzatropine
|
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| Other DBs |
|
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| LinkDB |
|
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| KCF data |
ATOM 28
1 S4a S 33.2140 -18.8297
2 C1a C 31.8828 -18.8243
3 O1d O 34.5508 -18.8297
4 O1d O 33.2084 -17.4986
5 O1d O 33.2084 -20.1610
6 C1x C 20.7530 -17.8020
7 C1x C 21.0706 -16.6678
8 C1y C 21.8872 -17.5298
9 C1y C 22.2047 -16.3956
10 N1y N 20.9799 -15.1254
11 C1x C 23.7018 -17.5298
12 C1x C 23.4296 -16.3956
13 C1y C 24.6999 -18.0742
14 O2a O 25.7433 -18.9362
15 C1a C 20.2548 -13.9791
16 C1c C 27.1433 -18.9362
17 C8y C 27.8622 -20.1811
18 C8y C 27.8331 -17.7424
19 C8x C 29.2596 -17.7435
20 C8x C 29.9605 -16.5316
21 C8x C 29.2614 -15.3186
22 C8x C 27.8349 -15.3175
23 C8x C 27.1340 -16.5294
24 C8x C 27.1708 -21.3786
25 C8x C 27.8707 -22.5911
26 C8x C 29.2707 -22.5912
27 C8x C 29.9621 -21.3937
28 C8x C 29.2622 -20.1812
BOND 30
1 1 2 1
2 1 3 1
3 1 4 2
4 1 5 2
5 6 7 1
6 6 8 1
7 7 9 1
8 8 10 1
9 8 11 1
10 9 12 1
11 11 13 1
12 13 14 1 #Down
13 9 10 1
14 12 13 1
15 10 15 1
16 14 16 1
17 16 17 1
18 16 18 1
19 18 19 2
20 19 20 1
21 20 21 2
22 21 22 1
23 22 23 2
24 18 23 1
25 17 24 2
26 24 25 1
27 25 26 2
28 26 27 1
29 27 28 2
30 17 28 1
|
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