| Entry |
|
|---|
| Name |
Trihexyphenidyl hydrochloride (JP18/USP);
Artane (TN) |
|---|
| Product |
|
|---|
| Generic |
TRIHEXYPHENIDYL HYDROCHLORIDE (A-S Medication Solutions), TRIHEXYPHENIDYL HYDROCHLORIDE (Actavis Pharma), TRIHEXYPHENIDYL HYDROCHLORIDE (Akorn), TRIHEXYPHENIDYL HYDROCHLORIDE (Bionpharma), TRIHEXYPHENIDYL HYDROCHLORIDE (Golden State Medical Supply), TRIHEXYPHENIDYL HYDROCHLORIDE (Natco Pharma Limited), TRIHEXYPHENIDYL HYDROCHLORIDE (Novitium Pharma LLC), TRIHEXYPHENIDYL HYDROCHLORIDE (PAI Holdings), TRIHEXYPHENIDYL HYDROCHLORIDE (REMEDYREPACK), TRIHEXYPHENIDYL HYDROCHLORIDE (REMEDYREPACK), TRIHEXYPHENIDYL HYDROCHLORIDE (REMEDYREPACK), TRIHEXYPHENIDYL HYDROCHLORIDE (REMEDYREPACK) |
|---|
| Formula |
C20H31NO. HCl
|
|---|
| Exact mass |
337.2172
|
|---|
| Mol weight |
337.93
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG01967 Antiparkinson agent
|
|---|
| Remark |
| Therapeutic category: | 1169 |
| Product (DG00851): | D00787<JP/US> |
|
|---|
| Efficacy |
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist |
|---|
| Disease |
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04A ANTICHOLINERGIC AGENTS
N04AA Tertiary amines
N04AA01 Trihexyphenidyl
D00787 Trihexyphenidyl hydrochloride (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Antiparkinson Agents
Anticholinergics
Trihexyphenidyl
D00787 Trihexyphenidyl hydrochloride (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
116 Antiparkinsonian agents
1169 Others
D00787 Trihexyphenidyl hydrochloride (JP18/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00851 Trihexyphenidyl
D00787 Trihexyphenidyl hydrochloride
DG01967 Antiparkinson agent
DG00851 Trihexyphenidyl
D00787 Trihexyphenidyl hydrochloride
Drug classes [BR:br08332]
Neuropsychiatric agent
DG01967 Antiparkinson agent
D00787 Trihexyphenidyl hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D00787 Trihexyphenidyl hydrochloride (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00787 Trihexyphenidyl hydrochloride
D00787 Trihexyphenidyl hydrochloride tablets
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00851 Trihexyphenidyl
DG01967 Antiparkinson agent
DG00851 Trihexyphenidyl
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 23
1 X Cl 29.1405 -19.5417
2 C8x C 27.3218 -23.9734
3 C8x C 28.5397 -23.2839
4 C8x C 28.5626 -21.9039
5 C8x C 27.3331 -21.1525
6 C8y C 26.1151 -21.8421
7 C8x C 26.1268 -23.2830
8 C1x C 26.1608 -19.0821
9 C1y C 24.9429 -19.7716
10 C1d C 24.9201 -21.1516
11 C1x C 26.1492 -17.6412
12 C1x C 24.9542 -16.9507
13 C1x C 23.7362 -17.6402
14 C1x C 23.7134 -19.0202
15 C1b C 23.7021 -21.8411
16 C1b C 22.5071 -21.1507
17 N1y N 21.2892 -21.8402
18 C1x C 20.0831 -21.1302
19 C1x C 18.8651 -21.8198
20 C1x C 18.8533 -23.2193
21 C1x C 20.0594 -23.9292
22 C1x C 21.2773 -23.2397
23 O1a O 26.1325 -20.4516
BOND 24
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 8 9 1
8 9 10 1
9 6 10 1
10 8 11 1
11 11 12 1
12 12 13 1
13 13 14 1
14 9 14 1
15 10 15 1
16 15 16 1
17 16 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 20 21 1
22 21 22 1
23 17 22 1
24 10 23 1
|
|---|
