| Entry |
|
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| Name |
Sulfamethizole (JP18/USP/INN);
Thiosulfil (TN) |
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| Formula |
C9H10N4O2S2
|
|---|
| Exact mass |
270.0245
|
|---|
| Mol weight |
270.34
|
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| Structure |
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| Simcomp |
|
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| Class |
Antibacterial
DG01787 Sulfonamide antibacterial
DG01784 Short-acting sulfonamide
|
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| Remark |
|
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| Efficacy |
Antibacterial, Folic acid biosynthesis inhibitor |
|---|
| Comment |
Sulfonamide
|
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| Target |
dihydropteroate synthase [KO: K00796] |
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| Pathway |
|
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| Interaction |
|
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| Structure map |
| map07016 | Sulfonamide derivatives - sulfa drugs |
| map07055 | Sulfonamide derivatives - overview |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
B05C IRRIGATING SOLUTIONS
B05CA Antiinfectives
B05CA04 Sulfamethizole
D00870 Sulfamethizole (JP18/USP/INN)
D DERMATOLOGICALS
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
D06B CHEMOTHERAPEUTICS FOR TOPICAL USE
D06BA Sulfonamides
D06BA04 Sulfamethizole
D00870 Sulfamethizole (JP18/USP/INN)
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01E SULFONAMIDES AND TRIMETHOPRIM
J01EB Short-acting sulfonamides
J01EB02 Sulfamethizole
D00870 Sulfamethizole (JP18/USP/INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AB Sulfonamides
S01AB01 Sulfamethizole
D00870 Sulfamethizole (JP18/USP/INN)
Drug groups [BR:br08330]
Antibacterial
DG01787 Sulfonamide antibacterial
DG01784 Short-acting sulfonamide
D00870 Sulfamethizole
Antimicrobials [BR:br08307]
Antibacterials
Folic acid biosynthesis inhibitor
Short-acting sulfonamide
D00870 Sulfamethizole (JP18/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00870 Sulfamethizole
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 17
1 C8y C 24.4406 -16.8002
2 S4a S 25.6548 -16.0880
3 C8x C 24.4463 -18.2013
4 C8x C 23.2262 -16.0996
5 N1b N 26.8632 -16.7885
6 O3c O 24.6507 -15.0955
7 O3c O 26.6414 -15.0955
8 C8x C 23.2321 -18.9019
9 C8x C 22.0820 -16.8061
10 C8y C 28.0717 -16.0822
11 C8y C 22.0177 -18.2072
12 S2x S 29.2801 -16.7828
13 N5x N 28.3693 -14.7219
14 N1a N 20.7918 -18.8959
15 C8y C 30.3193 -15.8486
16 N5x N 29.7471 -14.5759
17 C1a C 31.7204 -15.8428
BOND 18
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 2 6 2
6 2 7 2
7 3 8 2
8 4 9 1
9 5 10 1
10 8 11 1
11 10 12 1
12 10 13 2
13 11 14 1
14 12 15 1
15 13 16 1
16 15 17 1
17 9 11 2
18 15 16 2
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