KEGG   DRUG: Cefoperazone sodium
Entry
D00918                      Drug                                   
Name
Cefoperazone sodium (JP18/USP);
Cefobid (TN)
Formula
C25H26N9O8S2. Na
Exact mass
667.1243
Mol weight
667.65
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
 DG01776  Third-generation cephalosporin
Remark
Same as: C08112
ATC code: J01DD12
Chemical structure group: DG00581
Product (mixture): D08772<JP>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07012  Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DD Third-generation cephalosporins
     J01DD12 Cefoperazone
      D00918  Cefoperazone sodium (JP18/USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00581  Cefoperazone
      D00918  Cefoperazone sodium
  DG01776  Third-generation cephalosporin
   DG00581  Cefoperazone
    D00918  Cefoperazone sodium
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Third-generation cephalosporin
    D00918  Cefoperazone sodium (JP18/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00918  Cefoperazone sodium
  D00918  Cefoperazone sodium for injection
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00581  Cefoperazone
  DG01776  Third-generation cephalosporin
   DG00581  Cefoperazone
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Third-generation cephalosporin
    DG00581  Cefoperazone
Other DBs
CAS: 62893-20-3
PubChem: 7847981
ChEBI: 3494
LigandBox: D00918
NIKKAJI: J37.217J
LinkDB
KCF data

ATOM        45
            1   C1y C    29.6210  -17.0917
            2   N1y N    29.6210  -18.4695
            3   C2y C    30.8142  -19.1582
            4   C2y C    32.0074  -18.4695
            5   C1x C    32.0074  -17.0917
            6   S2x S    30.8142  -16.4028
            7   C1y C    28.2431  -17.0917
            8   C5x C    28.2431  -18.4695
            9   N1b N    27.0501  -16.4028
            10  C5a C    25.8567  -17.0917
            11  O5a O    25.8567  -18.4695
            12  O5x O    27.0501  -19.1582
            13  C1c C    24.6636  -16.4028
            14  C1b C    33.2189  -19.1692
            15  C6a C    30.8142  -20.5357
            16  O6a O    29.6044  -21.2343
            17  O6a O    31.9907  -21.2151 #-
            18  N1b N    23.4511  -17.1031
            19  C5a C    22.2594  -16.4150
            20  N1y N    21.0677  -17.1031
            21  S2a S    34.4169  -18.4777
            22  C8y C    35.6098  -19.1667
            23  N5x N    35.9908  -20.4873
            24  N5x N    37.3686  -20.5373
            25  N5x N    37.8420  -19.2425
            26  N4y N    36.7567  -18.3922
            27  O5a O    22.2595  -15.0376
            28  C5x C    19.8845  -16.4200
            29  C5x C    18.6909  -17.1089
            30  N1y N    18.6908  -18.4872
            31  C1x C    19.8741  -19.1703
            32  C1x C    21.0676  -18.4814
            33  O5x O    19.8845  -15.0378
            34  O5x O    17.4790  -16.4090
            35  C1b C    17.4826  -19.1849
            36  C1a C    16.2944  -18.4991
            37  C1a C    36.7359  -16.9955
            38  C8y C    24.6638  -14.9712
            39  C8x C    25.8698  -14.2750
            40  C8x C    25.8698  -12.8707
            41  C8y C    24.6538  -12.1685
            42  C8x C    23.4478  -12.8647
            43  C8x C    23.4477  -14.2689
            44  O1a O    24.6539  -10.7583
            45  Z   Na   33.3991  -21.2043 #+
BOND        48
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 1
            21   19  20 1
            22   14  21 1
            23   21  22 1
            24   22  23 2
            25   23  24 1
            26   24  25 2
            27   25  26 1
            28   22  26 1
            29   19  27 2
            30   20  28 1
            31   28  29 1
            32   29  30 1
            33   30  31 1
            34   31  32 1
            35   20  32 1
            36   28  33 2
            37   29  34 2
            38   30  35 1
            39   35  36 1
            40   26  37 1
            41   38  39 2
            42   39  40 1
            43   40  41 2
            44   41  42 1
            45   42  43 2
            46   38  43 1
            47   41  44 1
            48   13  38 1 #Down

» Japanese version   » Back

KEGG   DRUG: Cefoperazone
Entry
D07645                      Drug                                   
Name
Cefoperazone (INN);
Cefobid (TN);
Peracef [veterinary] (TN)
Formula
C25H27N9O8S2
Exact mass
645.1424
Mol weight
645.67
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
 DG01776  Third-generation cephalosporin
Remark
Same as: C06883
ATC code: J01DD12
Chemical structure group: DG00581
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07012  Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DD Third-generation cephalosporins
     J01DD12 Cefoperazone
      D07645  Cefoperazone (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00581  Cefoperazone
      D07645  Cefoperazone
  DG01776  Third-generation cephalosporin
   DG00581  Cefoperazone
    D07645  Cefoperazone
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Third-generation cephalosporin
    D07645  Cefoperazone (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00581  Cefoperazone
  DG01776  Third-generation cephalosporin
   DG00581  Cefoperazone
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Third-generation cephalosporin
    DG00581  Cefoperazone
Other DBs
CAS: 62893-19-0
PubChem: 51091949
ChEBI: 3493
LigandBox: D07645
NIKKAJI: J19.295C
LinkDB
KCF data

ATOM        44
            1   C1y C    26.7400  -19.0400
            2   N1y N    26.7400  -20.4400
            3   C2y C    28.0000  -21.1400
            4   C2y C    29.1900  -20.4400
            5   C1x C    29.1900  -19.0400
            6   S2x S    28.0000  -18.3400
            7   C1y C    25.4100  -19.0400
            8   C5x C    25.4100  -20.4400
            9   N1b N    24.1500  -18.3400
            10  C5a C    22.9600  -19.0400
            11  O5a O    22.9600  -20.4400
            12  O5x O    24.1500  -21.1400
            13  C1c C    21.7700  -18.3400
            14  C1b C    30.3800  -21.1400
            15  C6a C    28.0000  -22.5400
            16  O6a O    26.7400  -23.2400
            17  O6a O    29.1900  -23.2400
            18  N1b N    20.5100  -19.0400
            19  C5a C    19.3200  -18.3400
            20  N1y N    18.1300  -19.0400
            21  S2a S    31.6400  -20.4400
            22  C8y C    32.8300  -21.1400
            23  N5x N    33.2500  -22.4700
            24  N5x N    34.5800  -22.4700
            25  N5x N    35.0700  -21.2100
            26  N4y N    34.0200  -20.3700
            27  O5a O    19.3200  -17.0100
            28  C5x C    16.9400  -18.3400
            29  C5x C    15.6800  -19.0400
            30  N1y N    15.6800  -20.4400
            31  C1x C    16.8700  -21.1400
            32  C1x C    18.1300  -20.4400
            33  O5x O    16.9400  -17.0100
            34  O5x O    14.4900  -18.3400
            35  C1b C    14.4900  -21.1400
            36  C1a C    13.3000  -20.5100
            37  C1a C    33.9500  -18.9700
            38  C8y C    21.7700  -16.9400
            39  C8x C    22.9600  -16.1700
            40  C8x C    22.9600  -14.7700
            41  C8y C    21.7700  -14.0700
            42  C8x C    20.5100  -14.7700
            43  C8x C    20.5100  -16.1700
            44  O1a O    21.7700  -12.6700
BOND        48
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 1
            21   19  20 1
            22   14  21 1
            23   21  22 1
            24   22  23 2
            25   23  24 1
            26   24  25 2
            27   25  26 1
            28   22  26 1
            29   19  27 2
            30   20  28 1
            31   28  29 1
            32   29  30 1
            33   30  31 1
            34   31  32 1
            35   20  32 1
            36   28  33 2
            37   29  34 2
            38   30  35 1
            39   35  36 1
            40   26  37 1
            41   38  39 2
            42   39  40 1
            43   40  41 2
            44   41  42 1
            45   42  43 2
            46   38  43 1
            47   41  44 1
            48   13  38 1 #Down

» Japanese version   » Back

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