| Entry |
|
|---|
| Name |
Ceftizoxime sodium (JP18/USP);
Cefizox (TN);
Epocelin (TN) |
|---|
| Formula |
C13H12N5O5S2. Na
|
|---|
| Exact mass |
405.0178
|
|---|
| Mol weight |
405.39
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG01776 Third-generation cephalosporin
DG01804 Oxyimino beta-lactam
Transporter substrate
DG02860 SLC22A8 substrate
|
|---|
| Remark |
| Therapeutic category: | 6132 |
| Product (DG00576): | D00923<JP> |
|
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| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
|
|---|
| Metabolism |
Transporter: SLC22A8 [HSA: 9376]
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07012 | Cephalosporins - parenteral agents |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DD Third-generation cephalosporins
J01DD07 Ceftizoxime
D00923 Ceftizoxime sodium (JP18/USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D00923 Ceftizoxime sodium (JP18/USP)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00576 Ceftizoxime
D00923 Ceftizoxime sodium
DG01776 Third-generation cephalosporin
DG00576 Ceftizoxime
D00923 Ceftizoxime sodium
DG01804 Oxyimino beta-lactam
DG00576 Ceftizoxime
D00923 Ceftizoxime sodium
Transporter substrate
DG02860 SLC22A8 substrate
D00923 Ceftizoxime sodium
Drug classes [BR:br08332]
Antibacterial
DG01488 Cephem
D00923 Ceftizoxime sodium
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
D00923 Ceftizoxime sodium (JP18/USP) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00923 Ceftizoxime sodium
Drug metabolizing enzymes and transporters [br08309.html]
Drug transporters
D00923
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00576 Ceftizoxime
DG01776 Third-generation cephalosporin
DG00576 Ceftizoxime
DG01804 Oxyimino beta-lactam
DG00576 Ceftizoxime
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
DG00576 Ceftizoxime
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 26
1 C1y C 27.6266 -18.8498
2 N1y N 27.6266 -20.2389
3 C2y C 28.8298 -20.9335
4 C2x C 30.0328 -20.2389
5 C1x C 30.0328 -18.8498
6 S2x S 28.8298 -18.1552
7 C1y C 26.2373 -18.8498
8 C5x C 26.2373 -20.2389
9 N1b N 25.0345 -18.1552
10 C5a C 23.8313 -18.8498
11 O5a O 23.8313 -20.2389
12 O5x O 25.0345 -20.9335
13 C2c C 22.6281 -18.1552
14 C8y C 21.4059 -18.8613
15 C8x C 20.2754 -18.0309
16 S2x S 19.1316 -18.8479
17 C8y C 19.5551 -20.2580
18 N5x N 20.9606 -20.2695
19 N2b N 22.6280 -16.7447
20 C6a C 28.8298 -22.3394
21 O6a O 30.0435 -23.0401 #-
22 O6a O 27.6177 -23.0393
23 N1a N 18.7515 -21.3864
24 O2a O 23.8330 -16.0487
25 C1a C 23.8333 -14.6304
26 Z Na 31.5041 -22.9885 #+
BOND 27
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 13 14 1
16 14 15 2
17 15 16 1
18 16 17 1
19 17 18 2
20 14 18 1
21 13 19 2
22 3 20 1
23 20 21 1
24 20 22 2
25 17 23 1
26 19 24 1
27 24 25 1
|
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