Entry |
|
Name |
Lazabemide hydrochloride (JAN/USAN); Tempium (TN) |
Formula |
C8H10ClN3O. HCl
|
Exact mass |
235.0279
|
Mol weight |
236.10
|
Structure |
|
Simcomp |
|
Class |
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01512 Monoamine oxidase B inhibitor
|
Remark |
|
Efficacy |
Antiparkinsonian, Dementia therapeutic agent, Monoamine oxidase B (MAO-B) inhibitor |
Comment |
Treatment of Alzheimer's disease
|
Target |
|
Pathway |
|
Interaction |
|
Structure map |
map07216 | Catecholamine transferase inhibitors |
|
Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01512 Monoamine oxidase B inhibitor
DG01259 Lazabemide
D01097 Lazabemide hydrochloride
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Amine oxidases
MAOB
D01097 Lazabemide hydrochloride (JAN/USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01512 Monoamine oxidase B inhibitor
DG01259 Lazabemide
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 14
1 C8x C 20.4784 -19.0125
2 C8y C 20.4784 -20.4136
3 C8x C 21.6947 -21.1142
4 C8x C 22.9039 -20.4136
5 C8y C 22.9039 -19.0125
6 N5x N 21.6947 -18.3120
7 C5a C 24.1179 -18.3128
8 N1b N 25.3308 -19.0142
9 O5a O 24.1189 -16.9117
10 C1b C 26.5358 -18.3120
11 C1b C 27.7458 -19.0125
12 N1a N 28.9559 -18.3120
13 X Cl 19.2654 -21.1147
14 X Cl 32.6900 -18.3400
BOND 13
1 5 7 1
2 7 8 1
3 1 2 2
4 7 9 2
5 2 3 1
6 8 10 1
7 3 4 2
8 10 11 1
9 4 5 1
10 11 12 1
11 5 6 2
12 2 13 1
13 6 1 1
|