KEGG   DRUG: Ampicillin hydrate
Entry
D01251                      Drug                                   

Name
Ampicillin hydrate (JP18);
Ampicillin trihydrate;
Amcill (TN)
Product
  Generic
Formula
C16H19N3O4S. 3H2O
Exact mass
403.1413
Mol weight
403.4506
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01713  Penicillin skeleton group
   DG01480  Penam
 DG01780  Extended spectrum penicillin
Remark
Therapeutic category: 6131
ATC code: J01CA01 S01AA19
Chemical structure group: DG00517
Product (DG00517): D01251<JP/US> D02119<JP/US>
Product (mixture): D02502<JP>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
  Disease
Gonorrhea [DS:H00315]
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07011  Penicillins
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CA Penicillins with extended spectrum
     J01CA01 Ampicillin
      D01251  Ampicillin hydrate (JP18) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA19 Ampicillin
      D01251  Ampicillin hydrate (JP18) <JP/US>
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Penicillins
   Ampicillin
    D01251  Ampicillin hydrate (JP18)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6131  Penicillins
     D01251  Ampicillin hydrate (JP18)
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    D01251  Ampicillin hydrate (JP18) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01251  Ampicillin hydrate
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    DG00517  Ampicillin
Other DBs
CAS: 7177-48-2
PubChem: 7848314
ChEBI: 31209
ChEMBL: CHEMBL453388
DrugBank: DB00415
LigandBox: D01251
NIKKAJI: J1.587.797I
LinkDB
KCF data

ATOM        27
            1   C1y C    25.9451  -14.8660
            2   C5x C    25.9451  -16.2704
            3   N1y N    27.3495  -16.2704
            4   C1y C    27.3495  -14.8660
            5   C1y C    28.6836  -16.6916
            6   C1z C    29.5261  -15.5681
            7   S2x S    28.6836  -14.4446
            8   C1a C    30.5093  -16.5512
            9   C1a C    30.5093  -14.5850
            10  C6a C    29.1751  -18.0257
            11  O6a O    30.5794  -18.0257
            12  O6a O    28.3324  -19.1492
            13  N1b N    24.7514  -14.1638
            14  C5a C    23.5577  -14.8660
            15  O5x O    24.7514  -16.9725
            16  O5a O    23.5577  -16.2704
            17  C1c C    22.3386  -14.1687
            18  C8y C    21.1466  -14.8637
            19  N1a N    22.3386  -12.7679
            20  C8x C    19.9334  -14.1633
            21  C8x C    18.7203  -14.8637
            22  C8x C    18.7203  -16.2645
            23  C8x C    19.9334  -16.9649
            24  C8x C    21.1466  -16.2645
            25  O0  O    35.5115  -16.1114
            26  O0  O    35.5115  -16.1114
            27  O0  O    35.5115  -16.1114
BOND        26
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 1
            16    2  15 2
            17   14  16 2
            18   14  17 1
            19   17  18 1
            20   17  19 1 #Up
            21   18  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   18  24 1
BRACKET     1    33.5300  -17.0100   33.5300  -15.1900
            1    35.9800  -15.1900   35.9800  -17.0100
            1  3
 ORIGINAL  1   26
 REPEAT    1   27  28

» Japanese version   » Back

KEGG   DRUG: Ampicillin
Entry
D00204                      Drug                                   

Name
Ampicillin (USP/INN);
Anhydrous ampicillin (JP18);
Omnipen (TN)
Formula
C16H19N3O4S
Exact mass
349.1096
Mol weight
349.4048
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01713  Penicillin skeleton group
   DG01480  Penam
 DG01780  Extended spectrum penicillin
Remark
Same as: C06574
ATC code: J01CA01 S01AA19
Chemical structure group: DG00517
Product (DG00517): D01251<JP/US> D02119<JP/US>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07011  Penicillins
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CA Penicillins with extended spectrum
     J01CA01 Ampicillin
      D00204  Ampicillin (USP/INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA19 Ampicillin
      D00204  Ampicillin (USP/INN)
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    D00204  Ampicillin (USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00204  Anhydrous ampicillin
Prodrugs [br08324.html]
 D00204
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    DG00517  Ampicillin
Other DBs
CAS: 69-53-4
PubChem: 7847272
ChEBI: 28971
ChEMBL: CHEMBL174
DrugBank: DB00415
PDB-CCD: AIC[PDBj]
LigandBox: D00204
NIKKAJI: J4.515B
LinkDB
KCF data

ATOM        24
            1   C1y C    28.4025  -14.8702
            2   C5x C    28.4025  -16.2751
            3   N1y N    29.8073  -16.2751
            4   C1y C    29.8073  -14.8702
            5   C1y C    31.1418  -16.6964
            6   C1z C    31.9845  -15.5725
            7   S2x S    31.1418  -14.4487
            8   C1a C    32.9680  -16.5559
            9   C1a C    32.9680  -14.5892
            10  C6a C    31.6334  -18.0309
            11  O6a O    33.0381  -18.0309
            12  O6a O    30.7905  -19.1546
            13  N1b N    27.2084  -14.1678
            14  C5a C    26.0144  -14.8702
            15  O5x O    27.2084  -16.9774
            16  O5a O    26.0144  -16.2751
            17  C1c C    24.7949  -14.1727
            18  C8y C    23.6026  -14.8679
            19  N1a N    24.7949  -12.7715
            20  C8x C    22.3890  -14.1673
            21  C8x C    21.1757  -14.8679
            22  C8x C    21.1757  -16.2692
            23  C8x C    22.3890  -16.9698
            24  C8x C    23.6026  -16.2692
BOND        26
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 1
            16    2  15 2
            17   14  16 2
            18   14  17 1
            19   17  18 1
            20   17  19 1 #Up
            21   18  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   18  24 1

» Japanese version   » Back

KEGG   DRUG: Ampicillin sodium
Entry
D02119                      Drug                                   

Name
Ampicillin sodium (JP18/USP);
Omnipen-N (TN);
Viccillin (TN)
Product
  Generic
AMPICILLIN (Civica), AMPICILLIN (General Injectables and Vaccines), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Mylan Institutional LLC), AMPICILLIN (Piramal Critical Care), AMPICILLIN (Piramal Critical Care), AMPICILLIN (Sagent Pharmaceuticals), AMPICILLIN (WG Critical Care), AMPICILLIN (WG Critical Care), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Methapharm), AMPICILLIN (A-S Medication Solutions), AMPICILLIN (Athenex Pharmaceutical Division), AMPICILLIN (Athenex Pharmaceutical Division), AMPICILLIN (AuroMedics Pharma LLC), AMPICILLIN (AuroMedics Pharma LLC), AMPICILLIN (Fresenius Kabi USA), AMPICILLIN (Fresenius Kabi USA), AMPICILLIN (GC Hanford Manufacturing Company), AMPICILLIN (GC Hanford Manufacturing Company), AMPICILLIN (General Injectables and Vaccines), AMPICILLIN (General Injectables and Vaccines), AMPICILLIN (Hospira), AMPICILLIN (Hospira), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN SODIUM (Mylan Institutional LLC), AMPICILLIN (Sandoz), AMPICILLIN (Sandoz), AMPICILLIN (Sandoz), AMPICILLIN (Sandoz), AMPICILLIN (Sandoz), AMPICILLIN (Sandoz), AMPICILLIN (Sandoz)
Formula
C16H18N3O4S. Na
Exact mass
371.0916
Mol weight
371.3866
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01713  Penicillin skeleton group
   DG01480  Penam
 DG01780  Extended spectrum penicillin
Remark
Same as: C13652
Therapeutic category: 6131
ATC code: J01CA01 S01AA19
Chemical structure group: DG00517
Product (DG00517): D01251<JP/US> D02119<JP/US>
Product (mixture): D02065<JP/US> D02502<JP>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
  Disease
Bacterial endocarditis [DS:H00334]
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07011  Penicillins
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CA Penicillins with extended spectrum
     J01CA01 Ampicillin
      D02119  Ampicillin sodium (JP18/USP) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA19 Ampicillin
      D02119  Ampicillin sodium (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Penicillins
   Ampicillin
    D02119  Ampicillin sodium (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6131  Penicillins
     D02119  Ampicillin sodium (JP18/USP)
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    D02119  Ampicillin sodium (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02119  Ampicillin sodium
  D02119  Ampicillin sodium for injection
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    DG00517  Ampicillin
Other DBs
CAS: 69-52-3
PubChem: 7849180
ChEBI: 34535
ChEMBL: CHEMBL1078033 CHEMBL1200758
DrugBank: DB00415
LigandBox: D02119
NIKKAJI: J4.868B
LinkDB
KCF data

ATOM        25
            1   C1y C    28.4025  -14.8702
            2   C5x C    28.4025  -16.2751
            3   N1y N    29.8073  -16.2751
            4   C1y C    29.8073  -14.8702
            5   C1y C    31.1418  -16.6964
            6   C1z C    31.9845  -15.5725
            7   S2x S    31.1418  -14.4487
            8   C1a C    32.9680  -16.5559
            9   C1a C    32.9680  -14.5892
            10  C6a C    31.6334  -18.0309
            11  O6a O    33.0381  -18.0309 #-
            12  O6a O    30.7905  -19.1546
            13  N1b N    27.2084  -14.1678
            14  C5a C    26.0144  -14.8702
            15  O5x O    27.2084  -16.9774
            16  O5a O    26.0144  -16.2751
            17  C1c C    24.7949  -14.1727
            18  C8y C    23.6026  -14.8679
            19  N1a N    24.7949  -12.7715
            20  C8x C    22.3890  -14.1673
            21  C8x C    21.1757  -14.8679
            22  C8x C    21.1757  -16.2692
            23  C8x C    22.3890  -16.9698
            24  C8x C    23.6026  -16.2692
            25  Z   Na   34.5800  -18.0600 #+
BOND        26
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 1
            16    2  15 2
            17   14  16 2
            18   14  17 1
            19   17  18 1
            20   17  19 1 #Up
            21   18  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   18  24 1

» Japanese version   » Back

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