 | | DRUG: Methylphenidate hydrochloride | |
| Entry |
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| Name |
Methylphenidate hydrochloride (JAN/USP);
Concerta (TN);
Metadate (TN);
Quillivant xr (TN);
Ritalin (TN) |
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| Product |
APTENSIO XR (Rhodes Pharmaceuticals L.P.), CONCERTA (Janssen Pharmaceuticals), COTEMPLA XR-ODT (Neos Therapeutics Brands), METADATE CD (Aytu BioPharma), METHYLIN (SHIONOGI), METHYLPHENIDATE HYDROCHLORIDE (Patriot Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE (Trigen Laboratories), QUILLICHEW ER (NextWave Pharmaceuticals), QUILLIVANT (NextWave Pharmaceuticals), RELEXXII (Vertical Pharmaceuticals), RITALIN (Novartis Pharmaceuticals Corporation), RITALIN (Novartis Pharmaceuticals Corporation) |
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| Generic |
METHYLPHENIDATE (KVK-Tech), METHYLPHENIDATE (Sandoz), METHYLPHENIDATE HCL (Patrin Pharma), METHYLPHENIDATE HYDROCHLORIDE (Accord Healthcare), METHYLPHENIDATE HYDROCHLORIDE (Actavis Pharma), METHYLPHENIDATE HYDROCHLORIDE (Actavis Pharma), METHYLPHENIDATE HYDROCHLORIDE (American Health Packaging), METHYLPHENIDATE HYDROCHLORIDE (Amneal Pharmaceuticals LLC), METHYLPHENIDATE HYDROCHLORIDE (Amneal Pharmaceuticals of New York LLC), METHYLPHENIDATE HYDROCHLORIDE (Amneal Pharmaceuticals of New York LLC), METHYLPHENIDATE HYDROCHLORIDE (Ascend Laboratories), METHYLPHENIDATE HYDROCHLORIDE (Ascend Laboratories), METHYLPHENIDATE HYDROCHLORIDE (Ascent Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE (Aurolife Pharma), METHYLPHENIDATE HYDROCHLORIDE (AvPAK), METHYLPHENIDATE HYDROCHLORIDE (AvPAK), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Bryant Ranch Prepack), METHYLPHENIDATE HYDROCHLORIDE (Camber Pharmaceutical), METHYLPHENIDATE HYDROCHLORIDE (Camber Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE (Camber Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE (Dr.Reddys Laboratories), METHYLPHENIDATE HYDROCHLORIDE (Eywa Pharma), METHYLPHENIDATE HYDROCHLORIDE (Golden State Medical Supply), METHYLPHENIDATE HYDROCHLORIDE (Granules Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE (Granules Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE (KVK-TECH), METHYLPHENIDATE HYDROCHLORIDE (LA) (Mayne Pharma), METHYLPHENIDATE HYDROCHLORIDE (Lannett Company), METHYLPHENIDATE HYDROCHLORIDE (Lupin Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE (Lupin Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE (Lupin Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE (Neolpharma), METHYLPHENIDATE HYDROCHLORIDE (Nivagen Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE (Novel Laboratories), METHYLPHENIDATE HYDROCHLORIDE (QUAGEN PHARMACEUTICALS LLC), METHYLPHENIDATE HYDROCHLORIDE (Rhodes Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE (Rising Pharma Holdings), METHYLPHENIDATE HYDROCHLORIDE (Solco Healthcare US), METHYLPHENIDATE HYDROCHLORIDE (SpecGx LLC), METHYLPHENIDATE HYDROCHLORIDE (SpecGx LLC), METHYLPHENIDATE HYDROCHLORIDE (SpecGx LLC), METHYLPHENIDATE HYDROCHLORIDE (SpecGx LLC), METHYLPHENIDATE HYDROCHLORIDE (Sun Pharmaceutical Industries), METHYLPHENIDATE HYDROCHLORIDE (Sun Pharmaceutical Industries), METHYLPHENIDATE HYDROCHLORIDE (Teva Pharmaceuticals USA), METHYLPHENIDATE HYDROCHLORIDE (Teva Pharmaceuticals USA), METHYLPHENIDATE HYDROCHLORIDE (Trigen Laboratories), METHYLPHENIDATE HYDROCHLORIDE (Tris Pharma), METHYLPHENIDATE HYDROCHLORIDE (XLCare Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE (XLCare Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE (XLCare Pharmaceuticals), METHYLPHENIDATE HYDROCHLORIDE CD (Lannett Company), METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE (KVK-Tech) |
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| Formula |
C14H19NO2. HCl
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| Exact mass |
269.1183
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| Mol weight |
269.77
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| Structure |
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| Simcomp |
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| Class |
Neuropsychiatric agent
DG01971 Agents for narcolepsy
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| Remark |
| Therapeutic category: | 1179 |
| Product (DG00969): | D04999<US> D01296<JP/US> |
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| Efficacy |
Stimulant (central) |
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| Disease |
Attention deficit hyperactivity disorder [DS: H01895] Narcolepsy [DS: H01293] |
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| Comment |
piperidine derivative
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| Target |
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
N06BA Centrally acting sympathomimetics
N06BA04 Methylphenidate
D01296 Methylphenidate hydrochloride (JAN/USP) <JP/US>
USP drug classification [BR:br08302]
Central Nervous System Agents
Attention Deficit Hyperactivity Disorder Agents, Non-amphetamines
Methylphenidate
D01296 Methylphenidate hydrochloride (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
117 Psychotropics
1179 Others
D01296 Methylphenidate hydrochloride (JAN/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01971 Agents for narcolepsy
D01296 Methylphenidate hydrochloride
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D01296 Methylphenidate hydrochloride (JAN/USP) <JP/US>
SLC6A3 (DAT1)
D01296 Methylphenidate hydrochloride (JAN/USP) <JP/US>
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 18
1 C1c C 24.3131 -18.3693
2 C8y C 24.3014 -19.7673
3 C1y C 23.1133 -17.6530
4 C7a C 25.5364 -17.6763
5 C8x C 23.0840 -20.4546
6 C8x C 25.5072 -20.4779
7 C1x C 21.8959 -18.3403
8 N1x N 23.1307 -16.2550
9 O7a O 25.5538 -16.2783
10 O6a O 26.7421 -18.3926
11 C8x C 23.0724 -21.8583
12 C8x C 25.4898 -21.8759
13 C1x C 20.6902 -17.6296
14 C1x C 21.9249 -15.5385
15 C1a C 26.7712 -15.5910
16 C8x C 24.2665 -22.5689
17 C1x C 20.7018 -16.2258
18 X Cl 30.7573 -18.5477
BOND 18
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 1
9 4 10 2
10 5 11 1
11 6 12 2
12 7 13 1
13 8 14 1
14 9 15 1
15 11 16 2
16 13 17 1
17 12 16 1
18 14 17 1
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