KEGG   DRUG: Perazine maleate
Entry
D01412                      Drug                                   

Name
Perazine maleate (JAN)
Formula
C20H25N3S. (C4H4O4)2
Exact mass
571.1988
Mol weight
571.6419
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01905  Phenothiazine antipsychotics
Remark
ATC code: N05AB10
Chemical structure group: DG00881
Efficacy
Antipsychotic, Dopamine D2 receptor antagonist
Comment
Phenothiazine derivative
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Structure map
map07029  Antipsychotics - phenothiazines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AB Phenothiazines with piperazine structure
     N05AB10 Perazine
      D01412  Perazine maleate (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D01412  Perazine maleate (JAN)
Other DBs
CAS: 14516-56-4
PubChem: 7848475
ChEBI: 31979
LigandBox: D01412
NIKKAJI: J364.433B
LinkDB
KCF data

ATOM        40
            1   C8x C     8.9805  -16.6184
            2   C8x C     8.9805  -18.0205
            3   C8x C    10.1947  -18.7216
            4   C8y C    11.4090  -18.0205
            5   C8y C    11.4090  -16.6184
            6   C8x C    10.1947  -15.9174
            7   S2x S    12.6233  -18.7216
            8   C8y C    13.8375  -18.0205
            9   C8y C    13.8375  -16.6184
            10  N1y N    12.6233  -15.9174
            11  C8x C    15.0518  -18.7216
            12  C8x C    16.2660  -18.0205
            13  C8x C    16.2660  -16.6184
            14  C8x C    15.0518  -15.9174
            15  C1b C    12.6233  -14.5153
            16  C1b C    13.8396  -13.8130
            17  C1b C    15.0224  -14.4961
            18  N1y N    16.2141  -13.8080
            19  C1x C    17.4043  -14.4954
            20  C1x C    18.6176  -13.7951
            21  N1y N    18.6178  -12.3942
            22  C1x C    17.4275  -11.7067
            23  C1x C    16.2142  -12.4071
            24  C1a C    19.8444  -11.6859
            25  C6a C    24.0985  -17.2062
            26  C2b C    23.4234  -16.0415
            27  O6a O    23.4989  -18.4464
            28  O6a O    25.4491  -17.1999
            29  C2b C    21.8065  -16.0477
            30  C6a C    21.1375  -17.2185
            31  O6a O    19.7869  -17.2185
            32  O6a O    21.8190  -18.4525
            33  C6a C    24.0985  -17.2062
            34  C2b C    23.4234  -16.0415
            35  C2b C    21.8065  -16.0477
            36  C6a C    21.1375  -17.2185
            37  O6a O    19.7869  -17.2185
            38  O6a O    21.8190  -18.4525
            39  O6a O    23.4989  -18.4464
            40  O6a O    25.4491  -17.1999
BOND        41
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 1
            12    8  11 1
            13   11  12 2
            14   12  13 1
            15   13  14 2
            16    9  14 1
            17   10  15 1
            18   15  16 1
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   18  23 1
            27   21  24 1
            28   25  26 1
            29   25  27 1
            30   25  28 2
            31   26  29 2
            32   29  30 1
            33   30  31 1
            34   30  32 2
            35   33  34 1
            36   33  39 1
            37   33  40 2
            38   34  35 2
            39   35  36 1
            40   36  37 1
            41   36  38 2
BRACKET     1    18.6200  -18.9700   18.6200  -15.5400
            1    26.1100  -15.5400   26.1100  -18.9700
            1  2
 ORIGINAL  1   25  26  29  30  31  32  27  28
 REPEAT    1   33  34  35  36  37  38  39  40

» Japanese version   » Back

KEGG   DRUG: Perazine dimalonate
Entry
D01860                      Drug                                   

Name
Perazine dimalonate (JAN)
Formula
C20H25N3S. (C3H4O4)2
Exact mass
547.1988
Mol weight
547.6205
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01905  Phenothiazine antipsychotics
Remark
ATC code: N05AB10
Chemical structure group: DG00881
Efficacy
Antipsychotic, Dopamine D2 receptor antagonist
Comment
Phenothiazine derivative
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Structure map
map07029  Antipsychotics - phenothiazines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AB Phenothiazines with piperazine structure
     N05AB10 Perazine
      D01860  Perazine dimalonate (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D01860  Perazine dimalonate (JAN)
Other DBs
CAS: 14777-25-4
PubChem: 7848922
ChEBI: 31978
LigandBox: D01860
NIKKAJI: J369.086E
LinkDB
KCF data

ATOM        38
            1   N1y N    25.4022  -18.9095
            2   C8y C    24.1939  -19.6274
            3   C8y C    26.6107  -19.6217
            4   C1b C    25.4314  -17.5084
            5   C8y C    24.1881  -21.0286
            6   C8x C    22.9797  -18.9211
            7   C8y C    26.6048  -21.0286
            8   C8x C    27.8192  -18.9211
            9   C1b C    26.5990  -16.8019
            10  S2x S    25.4022  -21.7174
            11  C8x C    22.9797  -21.7174
            12  C8x C    21.7654  -19.6217
            13  C8x C    27.8075  -21.7231
            14  C8x C    29.0333  -19.6332
            15  C8x C    21.7713  -21.0286
            16  C8x C    29.0275  -21.0343
            17  C1b C    27.8200  -17.4868
            18  N1y N    28.9957  -16.7884
            19  C1x C    30.2096  -17.4694
            20  C1x C    31.4133  -16.7544
            21  N1y N    31.3960  -15.3545
            22  C1x C    30.1820  -14.6735
            23  C1x C    28.9783  -15.3885
            24  C1a C    32.6356  -14.6184
            25  O6a O    35.4767  -20.0324
            26  C6a C    36.6893  -19.3303
            27  C1b C    37.9022  -20.0255
            28  C6a C    39.1151  -19.3233
            29  O6a O    40.3280  -20.0183
            30  O6a O    36.6863  -17.9260
            31  O6a O    39.1120  -17.9190
            32  O6a O    35.4767  -20.0324
            33  C6a C    36.6893  -19.3303
            34  C1b C    37.9022  -20.0255
            35  C6a C    39.1151  -19.3233
            36  O6a O    40.3280  -20.0183
            37  O6a O    39.1120  -17.9190
            38  O6a O    36.6863  -17.9260
BOND        39
            1     3   8 1
            2     4   9 1
            3     5  10 1
            4     5  11 1
            5     6  12 2
            6     7  13 1
            7     8  14 2
            8    11  15 2
            9    13  16 2
            10    7  10 1
            11   12  15 1
            12   14  16 1
            13    1   2 1
            14    1   3 1
            15    1   4 1
            16    2   5 2
            17    2   6 1
            18    3   7 2
            19    9  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   18  23 1
            27   21  24 1
            28   25  26 1
            29   26  27 1
            30   27  28 1
            31   28  29 1
            32   26  30 2
            33   28  31 2
            34   32  33 1
            35   33  34 1
            36   34  35 1
            37   35  36 1
            38   33  38 2
            39   35  37 2
BRACKET     1    34.0900  -20.7200   34.0900  -16.9400
            1    41.6500  -16.9400   41.6500  -20.7200
            1  2
 ORIGINAL  1   25  26  27  28  29  31  30
 REPEAT    1   32  33  34  35  36  37  38

» Japanese version   » Back

KEGG   DRUG: Perazine fendizoate
Entry
D02608                      Drug                                   

Name
Perazine fendizoate (JAN)
Formula
(C20H14O4)2. C20H25N3S
Exact mass
975.3553
Mol weight
976.1431
Structure
Class
Neuropsychiatric agent
 DG01905  Phenothiazine antipsychotics
Remark
ATC code: N05AB10
Chemical structure group: DG00881
Efficacy
Antipsychotic, Dopamine D2 receptor antagonist
Comment
Phenothiazine derivative
Target
DRD2 [HSA:1813] [KO:K04145]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04728  Dopaminergic synapse
Interaction
Structure map
map07029  Antipsychotics - phenothiazines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AB Phenothiazines with piperazine structure
     N05AB10 Perazine
      D02608  Perazine fendizoate (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D02608  Perazine fendizoate (JAN)
Other DBs
PubChem: 17396778
LigandBox: D02608
LinkDB
KCF data

ATOM        72
            1   C8x C    19.2577  -19.4055
            2   C8x C    19.2577  -20.8067
            3   C8x C    20.4711  -21.5073
            4   C8y C    21.6846  -20.8067
            5   C8y C    21.6846  -19.4055
            6   C8x C    20.4711  -18.7050
            7   S2x S    22.8981  -21.5073
            8   C8y C    24.1115  -20.8067
            9   C8y C    24.1115  -19.4055
            10  N1y N    22.8981  -18.7050
            11  C8x C    25.3250  -21.5073
            12  C8x C    26.5384  -20.8067
            13  C8x C    26.5384  -19.4055
            14  C8x C    25.3250  -18.7050
            15  C1b C    22.8981  -17.3038
            16  C1b C    24.1136  -16.6020
            17  C1b C    25.2956  -17.2846
            18  N1y N    26.4865  -16.5970
            19  C1x C    27.6759  -17.2839
            20  C1x C    28.8884  -16.5841
            21  N1y N    28.8886  -15.1841
            22  C1x C    27.6991  -14.4971
            23  C1x C    26.4866  -15.1970
            24  C1a C    30.1144  -14.4763
            25  C8x C    32.4287  -19.3355
            26  C8x C    32.4287  -20.7367
            27  C8x C    33.6422  -21.4373
            28  C8x C    34.8557  -20.7367
            29  C8y C    34.8557  -19.3355
            30  C8y C    33.6422  -18.6350
            31  C6a C    33.6422  -17.2340
            32  O6a O    32.4119  -16.5235
            33  O6a O    34.8388  -16.5430
            34  C5a C    36.0878  -18.6239
            35  C8y C    37.2940  -19.3202
            36  O5a O    36.0875  -17.2339
            37  C8x C    37.2944  -20.7363
            38  C8x C    38.5081  -21.4366
            39  C8y C    39.7214  -20.7356
            40  C8y C    39.7209  -19.3194
            41  C8x C    38.5073  -18.6192
            42  C8y C    40.9227  -18.6252
            43  C8x C    42.1277  -19.3207
            44  C8x C    43.3411  -18.6200
            45  C8x C    43.3409  -17.2189
            46  C8x C    42.1358  -16.5233
            47  C8x C    40.9225  -17.2241
            48  O1a O    40.9306  -21.4333
            49  C8x C    32.4287  -19.3355
            50  C8x C    32.4287  -20.7367
            51  C8x C    33.6422  -21.4373
            52  C8x C    34.8557  -20.7367
            53  C8y C    34.8557  -19.3355
            54  C8y C    33.6422  -18.6350
            55  C6a C    33.6422  -17.2340
            56  O6a O    32.4119  -16.5235
            57  O6a O    34.8388  -16.5430
            58  C5a C    36.0878  -18.6239
            59  C8y C    37.2940  -19.3202
            60  C8x C    37.2944  -20.7363
            61  C8x C    38.5081  -21.4366
            62  C8y C    39.7214  -20.7356
            63  C8y C    39.7209  -19.3194
            64  C8x C    38.5073  -18.6192
            65  C8y C    40.9227  -18.6252
            66  C8x C    42.1277  -19.3207
            67  C8x C    43.3411  -18.6200
            68  C8x C    43.3409  -17.2189
            69  C8x C    42.1358  -16.5233
            70  C8x C    40.9225  -17.2241
            71  O1a O    40.9306  -21.4333
            72  O5a O    36.0875  -17.2339
BOND        79
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 1
            12    8  11 1
            13   11  12 2
            14   12  13 1
            15   13  14 2
            16    9  14 1
            17   10  15 1
            18   15  16 1
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   18  23 1
            27   21  24 1
            28   25  26 1
            29   26  27 2
            30   27  28 1
            31   28  29 2
            32   29  30 1
            33   25  30 2
            34   30  31 1
            35   31  32 1
            36   31  33 2
            37   29  34 1
            38   34  35 1
            39   34  36 2
            40   35  37 2
            41   37  38 1
            42   38  39 2
            43   39  40 1
            44   40  41 2
            45   35  41 1
            46   40  42 1
            47   42  43 2
            48   43  44 1
            49   44  45 2
            50   45  46 1
            51   46  47 2
            52   42  47 1
            53   39  48 1
            54   49  50 1
            55   50  51 2
            56   51  52 1
            57   52  53 2
            58   53  54 1
            59   49  54 2
            60   54  55 1
            61   55  56 1
            62   55  57 2
            63   53  58 1
            64   58  59 1
            65   58  72 2
            66   59  60 2
            67   60  61 1
            68   61  62 2
            69   62  63 1
            70   63  64 2
            71   59  64 1
            72   63  65 1
            73   65  66 2
            74   66  67 1
            75   67  68 2
            76   68  69 1
            77   69  70 2
            78   65  70 1
            79   62  71 1
BRACKET     1    31.2200  -21.9800   31.2200  -15.6100
            1    43.7500  -15.6100   43.7500  -21.9800
            1  2
 ORIGINAL  1   25  26  27  28  29  30  31  32  33  34  35  37  38  39  40  41
            1   42  43  44  45  46  47  48  36
 REPEAT    1   49  50  51  52  53  54  55  56  57  58  59  60  61  62  63  64
            1   65  66  67  68  69  70  71  72

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