| Entry |
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| Name |
Cefotiam hydrochloride (JP18/USP);
Ceradon (TN);
Pansporin (TN) |
|---|
| Formula |
C18H23N9O4S3. 2HCl
|
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| Exact mass |
597.0569
|
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| Mol weight |
598.55
|
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| Structure |
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| Simcomp |
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| Class |
|
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| Remark |
| Therapeutic category: | 6132 |
| Product (DG00563): | D01819<JP> |
|
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| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Target |
penicillin binding protein |
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| Pathway |
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| Interaction |
|
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| Structure map |
| map07012 | Cephalosporins - parenteral agents |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DC Second-generation cephalosporins
J01DC07 Cefotiam
D01819 Cefotiam hydrochloride (JP18/USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D01819 Cefotiam hydrochloride (JP18/USP)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00563 Cefotiam
D01819 Cefotiam hydrochloride
DG01775 Second-generation cephalosporin
DG00563 Cefotiam
D01819 Cefotiam hydrochloride
Drug classes [BR:br08332]
Antibacterial
DG01488 Cephem
D01819 Cefotiam hydrochloride
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Second-generation cephalosporin
D01819 Cefotiam hydrochloride (JP18/USP) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01819 Cefotiam hydrochloride
D01819 Cefotiam hydrochloride for injection
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00563 Cefotiam
DG01775 Second-generation cephalosporin
DG00563 Cefotiam
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Second-generation cephalosporin
DG00563 Cefotiam
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 36
1 C1y C 11.2206 -16.3740
2 N1y N 11.2206 -17.7676
3 C2y C 12.4277 -18.4643
4 C2y C 13.6347 -17.7676
5 C1x C 13.6347 -16.3740
6 S2x S 12.4277 -15.6771
7 C1y C 9.8268 -16.3740
8 C5x C 9.8268 -17.7676
9 N1b N 8.6200 -15.6771
10 C5a C 7.4128 -16.3740
11 O5a O 7.4128 -17.7676
12 O5x O 8.6200 -18.4643
13 C1b C 6.2058 -15.6771
14 C1b C 14.8602 -18.4755
15 C6a C 12.4277 -19.8579
16 O6a O 11.2038 -20.5647
17 O6a O 13.6177 -20.5452
18 C8y C 4.9794 -16.3856
19 S2a S 16.0721 -17.7760
20 C8y C 17.2788 -18.4730
21 N5x N 17.6839 -19.8742
22 N5x N 19.0782 -19.9044
23 N5x N 19.5378 -18.5177
24 N4y N 18.4274 -17.6737
25 C8x C 3.8295 -15.5758
26 S2x S 2.6994 -16.4195
27 C8y C 3.1525 -17.7550
28 N5x N 4.5626 -17.8069
29 C1b C 18.3879 -16.2408
30 C1b C 19.5969 -15.4975
31 N1c N 20.8190 -16.1586
32 C1a C 21.9853 -15.4412
33 C1a C 20.7884 -17.5683
34 N1a N 2.3031 -18.8948
35 X Cl 22.4700 -19.6700
36 X Cl 22.4700 -19.6700
BOND 37
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 3 15 1
17 15 16 2
18 15 17 1
19 13 18 1
20 14 19 1
21 19 20 1
22 20 21 2
23 21 22 1
24 22 23 2
25 23 24 1
26 20 24 1
27 18 25 2
28 25 26 1
29 26 27 1
30 27 28 2
31 18 28 1
32 24 29 1
33 29 30 1
34 30 31 1
35 31 32 1
36 31 33 1
37 27 34 1
BRACKET 1 20.8600 -20.3700 20.8600 -18.9700
1 23.2400 -18.9700 23.2400 -20.3700
1 2
ORIGINAL 1 36
REPEAT 1 37
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