| Entry |
|
|---|
| Name |
Ufenamate (JAN/INN);
Flufenamic acid butyl ester;
Combec (TN) |
|---|
| Formula |
C18H18F3NO2
|
|---|
| Exact mass |
337.129
|
|---|
| Mol weight |
337.3362
|
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| Structure |
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| Simcomp |
|
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| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
Dermatological agent
DG03243 Atopic dermatitis agent
|
|---|
| Remark |
| Therapeutic category: | 2649 |
| Product (DG00757): | D01823<JP> D03254<JP> |
|
|---|
| Efficacy |
Analgesic, Anti-inflammatory (topical), COX inhibitor |
|---|
| Comment |
Fenamic acid derivative
|
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| Target |
|
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AG Fenamates
M01AG03 Flufenamic acid
D01823 Ufenamate (JAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
26 Epidermides
264 Analgesics, anti-itchings, astringents, anti-inflammatory agents
2649 Others
D01823 Ufenamate (JAN/INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for integumentary system
57 Analgesic, antipruritic, astringent, and anti-inflammatory remedies (incl. gel patches)
D01823 Ufenamate (JAN/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Ufenamate
D01823 Ufenamate (JAN/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
DG00757 Flufenamic acid
D01823 Ufenamate
Dermatological agent
DG03243 Atopic dermatitis agent
D01823 Ufenamate
Drug classes [BR:br08332]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
D01823 Ufenamate
Dermatological agent
DG03243 Atopic dermatitis agent
D01823 Ufenamate
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D01823 Ufenamate (JAN/INN) <JP>
PTGS2 (COX2)
D01823 Ufenamate (JAN/INN) <JP>
Rx-to-OTC switch list in Japan [br08314.html]
D01823
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
DG00757 Flufenamic acid
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 24
1 C8x C 11.6200 -22.0500
2 C8x C 11.6200 -23.4500
3 C8x C 12.8800 -24.2200
4 C8x C 14.0700 -23.4500
5 C8y C 14.0700 -22.0500
6 C8y C 12.8800 -21.3500
7 C8x C 16.5200 -23.4500
8 C8y C 16.5200 -22.0500
9 N1b N 15.2600 -21.3500
10 C8x C 17.7100 -24.2200
11 C8x C 18.9000 -23.4500
12 C8y C 18.9000 -22.0500
13 C8x C 17.7100 -21.3500
14 C7a C 12.8800 -19.9500
15 O6a O 11.6200 -19.2500
16 O7a O 14.0700 -19.2500
17 C1b C 14.0700 -17.8500
18 C1b C 15.2824 -17.1500
19 C1b C 16.4779 -17.8404
20 C1a C 17.6653 -17.1549
21 C1d C 20.1153 -21.3549
22 X F 19.4153 -20.1425
23 X F 20.8153 -22.5674
24 X F 21.3277 -20.6549
BOND 25
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 8 2
8 8 9 1
9 5 9 1
10 7 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 8 13 1
15 6 14 1
16 14 15 2
17 14 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 12 21 1
23 21 22 1
24 21 23 1
25 21 24 1
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