KEGG   DRUG: p-Butylaminobenzoyldiethylaminoethyl hydrochloride
Entry
D01967                      Drug                                   
Name
p-Butylaminobenzoyldiethylaminoethyl hydrochloride (USAN);
Diethylaminoethyl p-butylaminobenzoate hydrochloride (JAN);
Calvital liquid (TN);
T cain (TN)
Formula
C17H29N2O2. Cl
Exact mass
328.1918
Mol weight
328.8774
Structure
Simcomp
Class
Neuropsychiatric agent
 DG02030  Anesthetics
  DG01675  Local anesthetic
Remark
Therapeutic category: 1211
Product: D01967<JP>
Product (mixture): D04814<JP> D04856<JP>
Efficacy
Anesthetic (local)
Comment
Component of Neoarsen black (TN), Neo-percamin S (TN), Neozalocaine (TN)
See [DR:D04856] Calvital powder (TN)
Target
SCN1A [HSA:6323] [KO:K04833]
SCN2A [HSA:6326] [KO:K04834]
SCN3A [HSA:6328] [KO:K04836]
SCN4A [HSA:6329] [KO:K04837]
SCN5A [HSA:6331] [KO:K04838]
SCN8A [HSA:6334] [KO:K04840]
SCN9A [HSA:6335] [KO:K04841]
SCN10A [HSA:6336] [KO:K04842]
SCN11A [HSA:11280] [KO:K04843]
Interaction
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   121  Local anesthetics
    1211  Aminobenzoate alkamine esters
     D01967  p-Butylaminobenzoyldiethylaminoethyl hydrochloride (USAN); Diethylaminoethyl p-butylaminobenzoate hydrochloride (JAN)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   diethylaminoethyl p-butylaminobenzoate hydrochloride
    D01967  p-Butylaminobenzoyldiethylaminoethyl hydrochloride (USAN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG02030  Anesthetics
   DG01675  Local anesthetic
    D01967  p-Butylaminobenzoyldiethylaminoethyl hydrochloride
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Sodium channels
    SCN1A
     D01967  p-Butylaminobenzoyldiethylaminoethyl hydrochloride (USAN) <JP>
    SCN2A
     D01967  p-Butylaminobenzoyldiethylaminoethyl hydrochloride (USAN) <JP>
    SCN3A
     D01967  p-Butylaminobenzoyldiethylaminoethyl hydrochloride (USAN) <JP>
    SCN4A
     D01967  p-Butylaminobenzoyldiethylaminoethyl hydrochloride (USAN) <JP>
    SCN5A
     D01967  p-Butylaminobenzoyldiethylaminoethyl hydrochloride (USAN) <JP>
    SCN8A
     D01967  p-Butylaminobenzoyldiethylaminoethyl hydrochloride (USAN) <JP>
    SCN9A
     D01967  p-Butylaminobenzoyldiethylaminoethyl hydrochloride (USAN) <JP>
    SCN10A
     D01967  p-Butylaminobenzoyldiethylaminoethyl hydrochloride (USAN) <JP>
    SCN11A
     D01967  p-Butylaminobenzoyldiethylaminoethyl hydrochloride (USAN) <JP>
Other DBs
CAS: 16488-48-5
PubChem: 7849029
LigandBox: D01967
NIKKAJI: J327.447K
LinkDB
KCF data

ATOM        22
            1   C8x C    16.1179  -12.1757
            2   C8y C    16.1179  -13.5753
            3   C8x C    17.3300  -14.2751
            4   C8x C    18.5420  -13.5753
            5   C8y C    18.5420  -12.1757
            6   C8x C    17.3300  -11.4760
            7   C7a C    19.7557  -11.4760
            8   O7a O    20.9678  -12.1757
            9   C1b C    22.1798  -11.4760
            10  C1b C    23.3918  -12.1757
            11  N1c N    24.6039  -11.4760 #+
            12  C1b C    25.8160  -12.1757
            13  C1a C    27.0280  -11.4760
            14  O6a O    19.7562  -10.0764
            15  C1b C    24.6039  -10.0764
            16  C1a C    25.8194   -9.3746
            17  N1b N    14.9059  -14.2751
            18  C1b C    13.6932  -13.5749
            19  C1b C    12.4800  -14.2753
            20  C1b C    11.2672  -13.5750
            21  C1a C    10.0542  -14.2753
            22  X   Cl   22.1793   -8.9090 #-
BOND        21
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14    7  14 2
            15   11  15 1
            16   15  16 1
            17    2  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1

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