| Entry |
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| Name |
Prednisolone hemisuccinate (USP);
Prednisolone succinate (JP18) |
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| Formula |
C25H32O8
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| Exact mass |
460.2097
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| Mol weight |
460.5168
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
| Product (DG00093): | D00472<JP/US> D00980<JP/US> D00981<JP/US> D01239<JP> D03301<JP> |
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| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AC Corticosteroids for local oral treatment
A01AC04 Prednisolone
D02156 Prednisolone hemisuccinate (USP)
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07E INTESTINAL ANTIINFLAMMATORY AGENTS
A07EA Corticosteroids acting locally
A07EA01 Prednisolone
D02156 Prednisolone hemisuccinate (USP)
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA04 Prednisolone
D02156 Prednisolone hemisuccinate (USP)
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AA Corticosteroids, weak (group I)
D07AA03 Prednisolone
D02156 Prednisolone hemisuccinate (USP)
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XA Corticosteroids, weak, other combinations
D07XA02 Prednisolone
D02156 Prednisolone hemisuccinate (USP)
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB06 Prednisolone
D02156 Prednisolone hemisuccinate (USP)
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD02 Prednisolone
D02156 Prednisolone hemisuccinate (USP)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA04 Prednisolone
D02156 Prednisolone hemisuccinate (USP)
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
S01CB Corticosteroids/antiinfectives/mydriatics in combination
S01CB02 Prednisolone
D02156 Prednisolone hemisuccinate (USP)
S02 OTOLOGICALS
S02B CORTICOSTEROIDS
S02BA Corticosteroids
S02BA03 Prednisolone
D02156 Prednisolone hemisuccinate (USP)
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03B CORTICOSTEROIDS
S03BA Corticosteroids
S03BA02 Prednisolone
D02156 Prednisolone hemisuccinate (USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00093 Prednisolone
D02156 Prednisolone hemisuccinate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D02156 Prednisolone hemisuccinate (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02156 Prednisolone succinate
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00093 Prednisolone
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 33
1 C1y C 21.8417 -19.6680
2 C1y C 20.6301 -20.3204
3 C1z C 21.8417 -18.2700
4 C1x C 24.2649 -19.6680
5 C1y C 19.4651 -19.6214
6 C1x C 20.6301 -21.7184
7 C1z C 23.0533 -17.6176
8 C1x C 20.6767 -17.5710
9 C1x C 24.2649 -18.3166
10 C1z C 18.2535 -20.3204
11 C1y C 19.4651 -18.2700
12 C1x C 19.4185 -22.4173
13 C5a C 23.0533 -15.8696
14 C2y C 18.2535 -21.7184
15 C2x C 17.0419 -19.6214
16 O1a O 18.2535 -17.5710
17 C1b C 24.2183 -15.1706
18 O5a O 21.8417 -15.1706
19 C2x C 17.0419 -22.4173
20 C2x C 15.8770 -20.3204
21 O7a O 25.4298 -15.8696
22 C5x C 15.8770 -21.7184
23 C7a C 26.5948 -15.1706
24 O5x O 14.6654 -22.4173
25 C1b C 27.8064 -15.8696
26 O6a O 26.5948 -13.7727
27 C1b C 29.0180 -15.1706
28 C6a C 30.2296 -15.8696
29 O6a O 31.3946 -15.1706
30 O6a O 30.2296 -17.2676
31 C1a C 21.8417 -16.8700
32 C1a C 18.2535 -18.9204
33 O1a O 24.2657 -16.9176
BOND 36
1 3 7 1
2 3 8 1
3 4 9 1
4 5 10 1
5 5 11 1
6 6 12 1
7 7 13 1 #Up
8 10 14 1
9 10 15 1
10 11 16 1 #Up
11 13 17 1
12 13 18 2
13 14 19 2
14 15 20 2
15 17 21 1
16 19 22 1
17 21 23 1
18 22 24 2
19 23 25 1
20 23 26 2
21 7 9 1
22 8 11 1
23 12 14 1
24 20 22 1
25 1 2 1
26 25 27 1
27 1 3 1
28 27 28 1
29 1 4 1
30 28 29 1
31 2 5 1
32 28 30 2
33 2 6 1
34 3 31 1 #Up
35 10 32 1 #Up
36 7 33 1 #Down
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