KEGG   DRUG: Atovaquone - proguanil hydrochloride mixtHelp
Entry
D02472            Mixture   Drug                                   

Name
Atovaquone - proguanil hydrochloride mixt;
Malarone (TN)
Product
  Generic
ATOVAQUONE AND PROGUANIL HYDROCHLORIDE (A-S Medication Solutions), ATOVAQUONE AND PROGUANIL HYDROCHLORIDE (Aidarex Pharmaceuticals LLC), ATOVAQUONE AND PROGUANIL HYDROCHLORIDE (Blenheim Pharmacal), ATOVAQUONE AND PROGUANIL HYDROCHLORIDE (BluePoint Laboratories), ATOVAQUONE AND PROGUANIL HCL (Bryant Ranch Prepack), ATOVAQUONE AND PROGUANIL HYDROCHLORIDE (Dispensing Solutions), ATOVAQUONE AND PROGUANIL HYDROCHLORIDE (Mylan Pharmaceuticals), ATOVAQUONE AND PROGUANIL HYDROCHLORIDE (PD-Rx Pharmaceuticals), ATOVAQUONE AND PROGUANIL HCL (PD-Rx Pharmaceuticals), ATOVAQUONE AND PROGUANIL HCL (Prasco Laboratories), ATOVAQUONE AND PROGUANIL HYDROCHLORIDE (Proficient Rx LP), ATOVAQUONE AND PROGUANIL HYDROCHLORIDE (Rebel Distributors Corp), ATOVAQUONE AND PROGUANIL HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), ATOVAQUONE AND PROGUANIL HYDROCHLORIDE PEDIATRIC (Glenmark Pharmaceuticals)
Formula
C22H19ClO3. C11H16ClN5. HCl
Exact mass
655.1884
Mol weight
657.0296
Structure
Mol fileKCF fileDB search
Component
Atovaquone [DR:D00236], Proguanil hydrochloride [DR:D02487]
Remark
Therapeutic category: 6419
ATC code: P01BB51
Product: D02472<JP/US>
Efficacy
Antimalarial
  Disease
Malaria [DS:H00361]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
  P01 ANTIPROTOZOALS
   P01B ANTIMALARIALS
    P01BB Biguanides
     P01BB51 Proguanil, combinations
      D02472  Atovaquone - proguanil hydrochloride mixt <JP/US>
USP drug classification [BR:br08302]
 Antiparasitics
  Antiprotozoals
   Atovaquone/Proguanil Hydrochloride
    D02472  Atovaquone - proguanil hydrochloride mixt
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  64  Parasitics (systemic)
   641  Antiprotozoans
    6419  Others
     D02472  Atovaquone - proguanil hydrochloride mixt
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D02472
BRITE hierarchy
Other DBs
CAS: 156879-69-5
PubChem: 17396658
LigandBox: D02472
LinkDB All DBs
KCF data Show

ATOM        44
            1   C8y C    32.0302  -19.1685
            2   N1b N    33.3493  -18.5207
            3   C8x C    32.0302  -20.5635
            4   C8x C    30.8278  -18.4681
            5   C2c C    34.5631  -19.2152
            6   C8x C    30.8278  -21.2640
            7   C8x C    29.6138  -19.1685
            8   N2b N    35.7714  -18.5207
            9   N1a N    34.5981  -20.6103
            10  C8y C    29.6138  -20.5635
            11  C2c C    35.7714  -17.1199
            12  X   Cl   28.3999  -21.2523
            13  N2b N    34.5631  -16.4253
            14  N1a N    36.9679  -16.4137
            15  C1c C    33.3493  -17.1199
            16  C1a C    32.1411  -16.4253
            17  C1a C    33.3434  -15.7251
            18  C2y C    18.6455  -18.4756
            19  C1y C    19.8509  -19.1803
            20  C5x C    17.4284  -19.1744
            21  C2y C    18.6512  -17.0722
            22  C1x C    19.8509  -20.5837
            23  C1x C    21.0680  -18.4756
            24  C8y C    16.2172  -18.4640
            25  O5x O    17.4225  -20.5720
            26  C5x C    17.4401  -16.3734
            27  O1a O    19.8626  -16.3792
            28  C1x C    21.0680  -21.2766
            29  C1x C    22.2734  -19.1803
            30  C8y C    16.2230  -17.0606
            31  C8x C    15.0175  -19.1687
            32  O5x O    17.4458  -14.9701
            33  C1y C    22.2734  -20.5837
            34  C8x C    15.0175  -16.3675
            35  C8x C    13.8004  -18.4640
            36  C8y C    23.4905  -21.2766
            37  C8x C    13.8004  -17.0606
            38  C8x C    23.4905  -22.6801
            39  C8x C    24.7074  -20.5837
            40  C8x C    24.7074  -23.3847
            41  C8x C    25.9128  -21.2766
            42  C8y C    25.9128  -22.6801
            43  X   Cl   27.1299  -23.3789
            44  X   Cl   35.1397  -23.1232
BOND        46
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 2
            8     5   9 1
            9     6  10 1
            10    8  11 1
            11   10  12 1
            12   11  13 2
            13   11  14 1
            14   13  15 1
            15   15  16 1
            16   15  17 1
            17    7  10 2
            18   18  19 1
            19   18  20 1
            20   18  21 2
            21   19  22 1
            22   19  23 1
            23   20  24 1
            24   20  25 2
            25   21  26 1
            26   21  27 1
            27   22  28 1
            28   23  29 1
            29   24  30 1
            30   24  31 2
            31   26  32 2
            32   28  33 1
            33   30  34 2
            34   31  35 1
            35   33  36 1
            36   34  37 1
            37   36  38 2
            38   36  39 1
            39   38  40 1
            40   39  41 2
            41   40  42 2
            42   42  43 1
            43   26  30 1
            44   29  33 1
            45   35  37 2
            46   41  42 1

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