KEGG   DRUG: Nasaruplase (cell culture)
Entry
D03324                      Drug                                   

Name
Nasaruplase (cell culture) (JAN);
Prourokinase (plasminogen activator prolyse)
Formula
C2031H3121N585O601S31
Exact mass
46313.2981
Mol weight
46343.0863
Class
Cardiovascular agent
 DG01950  Antithrombotic agent
  DG01707  Fibrinolytic
   DG01701  Urokinase-type plasminogen activator
 DG01707  Fibrinolytic
  DG01701  Urokinase-type plasminogen activator
Remark
Chemical structure group: DG01700
Efficacy
Thrombolytic, Urokinase plasminogen activator (u-PA)
Comment
urokinase plasminogen activator (u-PA) [HSA:5328] [KO:K01348] [EC:3.4.21.73]
Interaction
Structure map
map07049  Antithrombosis agents
Other DBs
CAS: 82657-92-9
PubChem: 17397474
LinkDB

» Japanese version   » Back

KEGG   DRUG: Nasaruplase beta
Entry
D05123                      Drug                                   

Name
Nasaruplase beta (USAN/INN);
Prolyse (TN)
Formula
C2031H3121N585O601S31
Exact mass
46313.2981
Mol weight
46343.0863
Sequence
SNELHQVPSN CDCLNGGTCV SNKYFSNIHW CNCPKKFGGQ HCEIDKSKTC YEGNGHFYRG
KASTDTMGRP CLPWNSATVL QQTYHAHRSD ALQLGLGKHN YCRNPDNRRR PWCYVQVGLK
PLVQECMVHD CADGKKPSSP PEELKFQCGQ KTLRPRFKII GGEFTTIENQ PWFAAIYRRH
RGGSVTYVCG GSLISPCWVI SATHCFIDYP KKEDYIVYLG RSRLNSNTQG EMKFEVENLI
LHKDYSADTL AHHNDIALLK IRSKEGRCAQ PSRTIQTICL PSMYNDPQFG TSCEITGFGK
ENSTDYLYPE QLKMTVVKLI SHRECQQPHY YGSEVTTKML CAADPQWKTD SCQGDSGGPL
VCSLQGRMTL TGIVSWGRGC ALKDKPGVYT RVSHFLPWIR SHTKEENGLA L
(Disulfide bridge: 11-19, 13-31, 33-42, 50-131, 71-113, 102-126, 148-279, 189-205, 197-268, 293-362, 325-341, 352-380; Glycosylation site: 18, 302)
  Type
Peptide
Class
Cardiovascular agent
 DG01950  Antithrombotic agent
  DG01707  Fibrinolytic
   DG01701  Urokinase-type plasminogen activator
 DG01707  Fibrinolytic
  DG01701  Urokinase-type plasminogen activator
Remark
Chemical structure group: DG01700
Efficacy
Fibrinolytic, Thrombolytic, Stroke treatment, Urokinase plasminogen activator (u-PA)
Comment
urokinase plasminogen activator (u-PA) [HSA:5328] [KO:K01348] [EC:3.4.21.73]
Treatment of acute ischemic stroke
Interaction
Structure map
map07049  Antithrombosis agents
Other DBs
CAS: 136653-69-5
PubChem: 47206848
LinkDB

» Japanese version   » Back

DBGET integrated database retrieval system