KEGG   DRUG: Cefbuperazone
Entry
D03423                      Drug                                   
Name
Cefbuperazone (USAN/INN)
Formula
C22H29N9O9S2
Exact mass
627.1530
Mol weight
627.66
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
 DG01775  Second-generation cephalosporin
Remark
ATC code: J01DC13
Chemical structure group: DG00568
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07012  Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DC Second-generation cephalosporins
     J01DC13 Cefbuperazone
      D03423  Cefbuperazone (USAN/INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00568  Cefbuperazone
      D03423  Cefbuperazone
  DG01775  Second-generation cephalosporin
   DG00568  Cefbuperazone
    D03423  Cefbuperazone
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Second-generation cephalosporin
    D03423  Cefbuperazone (USAN/INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00568  Cefbuperazone
  DG01775  Second-generation cephalosporin
   DG00568  Cefbuperazone
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Second-generation cephalosporin
    DG00568  Cefbuperazone
Other DBs
CAS: 76610-84-9
PubChem: 17397563
ChEBI: 135856
LigandBox: D03423
NIKKAJI: J34.489C
LinkDB
KCF data

ATOM        42
            1   C1y C    29.6623  -15.4821
            2   N1y N    29.6623  -16.8556
            3   C2y C    30.8518  -17.5422
            4   C2y C    32.0413  -16.8556
            5   C1x C    32.0413  -15.4821
            6   S2x S    30.8518  -14.7954
            7   C1z C    28.2888  -15.4821
            8   C5x C    28.2888  -16.8556
            9   N1b N    27.0995  -14.7954
            10  C5a C    25.9099  -15.4821
            11  O5a O    25.9099  -16.8556
            12  O5x O    27.0995  -17.5422
            13  C1c C    24.7205  -14.7954
            14  C1b C    33.2490  -17.5532
            15  C6a C    30.8518  -18.9154
            16  O6a O    29.6458  -19.6118
            17  O6a O    32.0246  -19.5926
            18  N1b N    23.5119  -15.4936
            19  C5a C    22.3239  -14.8076
            20  N1y N    21.1359  -15.4936
            21  C1c C    24.7205  -13.0740
            22  S2a S    34.4432  -16.8638
            23  C8y C    35.6324  -17.5507
            24  N5x N    36.0989  -18.8413
            25  N5x N    37.4726  -18.7996
            26  N5x N    37.8575  -17.4802
            27  N4y N    36.7217  -16.7065
            28  O2a O    28.2888  -13.2840
            29  C1a C    29.4757  -12.5987
            30  O1a O    25.9030  -12.3914
            31  C1a C    23.5383  -12.3915
            32  O5a O    22.3240  -13.4345
            33  C5x C    19.9564  -14.8125
            34  C5x C    18.7666  -15.4994
            35  N1y N    18.7665  -16.8733
            36  C1x C    19.9461  -17.5543
            37  C1x C    21.1358  -16.8675
            38  O5x O    19.9564  -13.4347
            39  O5x O    17.5585  -14.8016
            40  C1b C    17.5621  -17.5688
            41  C1a C    16.3777  -16.8851
            42  C1a C    36.7217  -15.3078
BOND        45
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 1
            21   19  20 1
            22   13  21 1
            23   14  22 1
            24   22  23 1
            25   23  24 2
            26   24  25 1
            27   25  26 2
            28   26  27 1
            29   23  27 1
            30    7  28 1 #Down
            31   28  29 1
            32   21  30 1 #Down
            33   21  31 1
            34   19  32 2
            35   20  33 1
            36   33  34 1
            37   34  35 1
            38   35  36 1
            39   36  37 1
            40   20  37 1
            41   33  38 2
            42   34  39 2
            43   35  40 1
            44   40  41 1
            45   27  42 1

» Japanese version   » Back

KEGG   DRUG: Cefbuperazone sodium
Entry
D01736                      Drug                                   
Name
Cefbuperazone sodium (JP18);
Keiperazon (TN)
Formula
C22H28N9O9S2. Na
Exact mass
649.1349
Mol weight
649.64
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
 DG01775  Second-generation cephalosporin
Remark
ATC code: J01DC13
Chemical structure group: DG00568
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07012  Cephalosporins - parenteral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DC Second-generation cephalosporins
     J01DC13 Cefbuperazone
      D01736  Cefbuperazone sodium (JP18)
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00568  Cefbuperazone
      D01736  Cefbuperazone sodium
  DG01775  Second-generation cephalosporin
   DG00568  Cefbuperazone
    D01736  Cefbuperazone sodium
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Second-generation cephalosporin
    D01736  Cefbuperazone sodium (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01736  Cefbuperazone sodium
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00568  Cefbuperazone
  DG01775  Second-generation cephalosporin
   DG00568  Cefbuperazone
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Second-generation cephalosporin
    DG00568  Cefbuperazone
Other DBs
CAS: 76648-01-6
PubChem: 7848799
ChEBI: 31365
LigandBox: D01736
NIKKAJI: J23.598I
LinkDB
KCF data

ATOM        43
            1   C1y C    29.6656  -15.4841
            2   N1y N    29.6656  -16.8577
            3   C2y C    30.8552  -17.5443
            4   C2y C    32.0448  -16.8577
            5   C1x C    32.0448  -15.4841
            6   S2x S    30.8552  -14.7973
            7   C1z C    28.2919  -15.4841
            8   C5x C    28.2919  -16.8577
            9   N1b N    27.1025  -14.7973
            10  C5a C    25.9127  -15.4841
            11  O5a O    25.9127  -16.8577
            12  O5x O    27.1025  -17.5443
            13  C1c C    24.7232  -14.7973
            14  C1b C    33.2526  -17.5553
            15  C6a C    30.8552  -18.9177
            16  O6a O    29.6491  -19.6142
            17  O6a O    32.0281  -19.5950 #-
            18  N1b N    23.5144  -15.4955
            19  C5a C    22.3263  -14.8095
            20  N1y N    21.1382  -15.4955
            21  C1c C    24.7232  -13.0757
            22  S2a S    34.4470  -16.8659
            23  C8y C    35.6363  -17.5528
            24  N5x N    36.0161  -18.8694
            25  N5x N    37.3897  -18.9193
            26  N5x N    37.8617  -17.6284
            27  N4y N    36.7797  -16.7807
            28  O2a O    28.2919  -13.2857
            29  C1a C    29.4789  -12.6004
            30  O1a O    25.9058  -12.3930
            31  C1a C    23.5408  -12.3931
            32  O5a O    22.3264  -13.4363
            33  C5x C    19.9586  -14.8144
            34  C5x C    18.7686  -15.5013
            35  N1y N    18.7685  -16.8754
            36  C1x C    19.9483  -17.5564
            37  C1x C    21.1381  -16.8696
            38  O5x O    19.9586  -13.4365
            39  O5x O    17.5604  -14.8035
            40  C1b C    17.5640  -17.5710
            41  C1a C    16.3794  -16.8872
            42  C1a C    36.7590  -15.3882
            43  Z   Na   33.4323  -19.5842 #+
BOND        45
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 1
            21   19  20 1
            22   13  21 1
            23   14  22 1
            24   22  23 1
            25   23  24 2
            26   24  25 1
            27   25  26 2
            28   26  27 1
            29   23  27 1
            30    7  28 1 #Down
            31   28  29 1
            32   21  30 1 #Down
            33   21  31 1
            34   19  32 2
            35   20  33 1
            36   33  34 1
            37   34  35 1
            38   35  36 1
            39   36  37 1
            40   20  37 1
            41   33  38 2
            42   34  39 2
            43   35  40 1
            44   40  41 1
            45   27  42 1

» Japanese version   » Back

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