KEGG   DRUG: Lenercept
Entry
D04690                      Drug                                   
Name
Lenercept (USAN/INN)
Formula
C1993H3112N562O624S34
Exact mass
45989.9562
Mol weight
46019.6354
Class
Anti-inflammatory
 DG01985  Disease modifying anti-rheumatic drug (DMARD)
  DG01936  TNF inhibitor
Efficacy
Anti-inflammatory, Immunomodulator, TNF inhibitor
Comment
recombinant humanised fusion protein of TNF-R1 and IgG1 heave chain
Target
TNF (TNFA, TNFSF2) [HSA:7124] [KO:K03156]
LTA (TNFB, TNFSF1) [HSA:4049] [KO:K05468]
LTB (TNFC, TNFSF3) [HSA:4050] [KO:K03157]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04064  NF-kappa B signaling pathway
hsa04668  TNF signaling pathway
Interaction
Brite
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01985  Disease modifying anti-rheumatic drug (DMARD)
   DG01936  TNF inhibitor
    D04690  Lenercept
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokines
   Tumor necrosis factors
    TNF (TNFA, TNFSF2)
     D04690  Lenercept (USAN/INN)
    LTA (TNFB, TNFSF1)
     D04690  Lenercept (USAN/INN)
    LTB (TNFC, TNFSF3)
     D04690  Lenercept (USAN/INN)
Other DBs
CAS: 156679-34-4
PubChem: 47206524
LinkDB

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