KEGG   DRUG: Rioprostil
Entry
D05732                      Drug                                   

Name
Rioprostil (USAN/INN)
Formula
C21H38O4
Exact mass
354.277
Mol weight
354.524
Structure
Simcomp
Class
Cardiovascular agent
 DG01611  Prostaglandin E1 derivative
Other
 DG01961  Prostaglandin derivative
  DG01611  Prostaglandin E1 derivative
 DG02573  Prostanoid derivative
  DG01961  Prostaglandin derivative
   DG01611  Prostaglandin E1 derivative
Efficacy
Antisecretory (gastric acid), Prostaglandin E2 receptor agonist
Comment
Prostaglandin derivative
Target
PTGER2 [HSA:5732] [KO:K04259]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07228  Eicosanoid receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Prostaglandin
    PTGER2
     D05732  Rioprostil (USAN/INN)
Other DBs
CAS: 77287-05-9
PubChem: 47207393
ChEMBL: CHEMBL3301679
LigandBox: D05732
NIKKAJI: J138.368J
LinkDB
KCF data

ATOM        25
            1   C1y C    19.4600  -21.8400
            2   C1y C    19.4600  -23.2400
            3   C5x C    18.1300  -21.4200
            4   C1b C    20.7200  -20.7900
            5   C1y C    18.1300  -23.7300
            6   C2b C    20.7200  -24.2900
            7   C1x C    17.3600  -22.6100
            8   O5x O    17.7100  -20.1600
            9   O1a O    17.7100  -24.9900
            10  C2b C    21.9100  -23.5900
            11  C1b C    23.1000  -24.2900
            12  C1d C    24.2900  -23.5900
            13  C1b C    25.4800  -24.2900
            14  C1b C    26.7400  -23.5900
            15  C1b C    27.9300  -24.2900
            16  C1a C    29.1200  -23.5900
            17  C1b C    21.9100  -21.4900
            18  C1b C    23.1000  -20.7900
            19  C1b C    24.2900  -21.4900
            20  C1b C    25.4800  -20.7900
            21  C1b C    26.6700  -21.4900
            22  C1b C    27.8600  -20.7900
            23  O1a O    29.1200  -21.4900
            24  O1a O    25.2700  -22.6100
            25  C1a C    23.3100  -22.6100
BOND        25
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     3   8 2
            8     5   9 1 #Down
            9     6  10 2
            10   10  11 1
            11   11  12 1
            12   12  13 1
            13   13  14 1
            14   14  15 1
            15   15  16 1
            16    5   7 1
            17    4  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1
            22   21  22 1
            23   22  23 1
            24   12  24 1
            25   12  25 1

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