KEGG   DRUG: Vidarabine
Entry
D06298                      Drug                                   

Name
Vidarabine (JAN);
Vidarabine anhydrous;
ARA-A;
Armes (TN)
Formula
C10H13N5O4
Exact mass
267.0968
Mol weight
267.2413
Structure
Simcomp
Class
Antiviral
 DG01440  Arabinofuranosyl type antiviral
 DG02840  Anti-herpesvirus agent
Remark
Therapeutic category: 6250
ATC code: J05AB03 S01AD06
Chemical structure group: DG00645
Product (DG00645): D06298<JP>
Efficacy
Antiviral, DNA polymerase inhibitor
Comment
Arabinofuranosyl derivative
Target
Herpesvirus DNA polymerase [KO:K18964]
Interaction
Structure map
map07041  Antineoplastics - antimetabolic agents
map07044  Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB03 Vidarabine
      D06298  Vidarabine (JAN) <JP>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AD Antivirals
     S01AD06 Vidarabine
      D06298  Vidarabine (JAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D06298  Vidarabine (JAN)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for integumentary system
  91 Antivirals
   D06298  Vidarabine (JAN)
Risk category of Japanese OTC drugs [BR:br08312]
 First-class OTC drugs
  Inorganic and organic chemicals
   Vidarabine
    D06298  Vidarabine (JAN)
Antimicrobials [BR:br08307]
 Antivirals
  Genome replication inhibitor
   Herpesvirus DNA polymerase inhibitor
    D06298  Vidarabine (JAN) <JP>
Rx-to-OTC switch list in Japan [br08314.html]
 D06298
Antimicrobials abbreviations [BR:br08327]
 Antivirals
  Genome replication inhibitor
   Herpesvirus DNA polymerase inhibitor
    DG00645  Vidarabine
Other DBs
CAS: 5536-17-4
PubChem: 47207955
ChEMBL: CHEMBL1090 CHEMBL20247
DrugBank: DB00194
PDB-CCD: RAB[PDBj]
LigandBox: D06298
NIKKAJI: J3.415K
LinkDB
KCF data

ATOM        19
            1   N4y N    24.4593  -17.9096
            2   C8y C    25.5947  -18.7423
            3   C1y C    23.1374  -18.3465
            4   C8x C    24.8960  -16.5880
            5   C8y C    26.7243  -17.9213
            6   N5x N    25.7286  -20.1282
            7   O2x O    22.0020  -17.5196
            8   C1y C    22.6949  -19.6798
            9   N5x N    26.2992  -16.5880
            10  C8y C    27.9995  -18.4978
            11  C8x C    27.0039  -20.6989
            12  C1y C    20.8606  -18.3465
            13  C1y C    21.2972  -19.6798
            14  O1a O    23.5218  -20.8095
            15  N5x N    28.1393  -19.8896
            16  N1a N    29.1409  -17.6768
            17  C1b C    19.5272  -17.9096
            18  O1a O    20.4762  -20.8095
            19  O1a O    18.4907  -18.8531
BOND        21
            1     1   2 1
            2     3   1 1 #Up
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 2
            11    7  12 1
            12    8  13 1
            13    8  14 1 #Up
            14   10  15 2
            15   10  16 1
            16   12  17 1 #Up
            17   13  18 1 #Down
            18   17  19 1
            19    5   9 1
            20   11  15 1
            21   12  13 1

» Japanese version   » Back

KEGG   DRUG: Vidarabine
Entry
D00406                      Drug                                   

Name
Vidarabine (USAN);
Vidarabine monohydrate;
Vira-A (TN)
Formula
C10H13N5O4. H2O
Exact mass
285.1073
Mol weight
285.2566
Structure
Simcomp
Class
Antiviral
 DG01440  Arabinofuranosyl type antiviral
 DG02840  Anti-herpesvirus agent
Remark
Same as: C07195
ATC code: J05AB03 S01AD06
Chemical structure group: DG00645
Product (DG00645): D06298<JP>
Efficacy
Antiviral, DNA polymerase inhibitor
Comment
Arabinofuranosyl derivative
Target
Herpesvirus DNA polymerase [KO:K18964]
Interaction
Structure map
map07041  Antineoplastics - antimetabolic agents
map07044  Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB03 Vidarabine
      D00406  Vidarabine (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AD Antivirals
     S01AD06 Vidarabine
      D00406  Vidarabine (USAN)
Antimicrobials [BR:br08307]
 Antivirals
  Genome replication inhibitor
   Herpesvirus DNA polymerase inhibitor
    D00406  Vidarabine (USAN)
Antimicrobials abbreviations [BR:br08327]
 Antivirals
  Genome replication inhibitor
   Herpesvirus DNA polymerase inhibitor
    DG00645  Vidarabine
Other DBs
CAS: 24356-66-9
PubChem: 7847472
ChEBI: 9978
DrugBank: DB00194
LigandBox: D00406
NIKKAJI: J1.592.461F
LinkDB
KCF data

ATOM        20
            1   N4y N    24.1094  -17.9097
            2   C8y C    25.2448  -18.7424
            3   C1y C    22.7875  -18.3466
            4   C8x C    24.5461  -16.5881
            5   C8y C    26.3744  -17.9214
            6   N5x N    25.3787  -20.1283
            7   O2x O    21.6521  -17.5197
            8   C1y C    22.3450  -19.6799
            9   N5x N    25.9493  -16.5881
            10  C8y C    27.6496  -18.4979
            11  C8x C    26.6540  -20.6990
            12  C1y C    20.5107  -18.3466
            13  C1y C    20.9473  -19.6799
            14  O1a O    23.1719  -20.8096
            15  N5x N    27.7894  -19.8897
            16  N1a N    28.7910  -17.6769
            17  C1b C    19.1773  -17.9097
            18  O1a O    20.1263  -20.8096
            19  O1a O    18.1408  -18.8532
            20  O0  O    30.8800  -19.5252
BOND        21
            1     1   2 1
            2     3   1 1 #Up
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 2
            11    7  12 1
            12    8  13 1
            13    8  14 1 #Up
            14   10  15 2
            15   10  16 1
            16   12  17 1 #Up
            17   13  18 1 #Down
            18   17  19 1
            19    5   9 1
            20   11  15 1
            21   12  13 1

» Japanese version   » Back

KEGG   DRUG: Vidarabine sodium phosphate
Entry
D06300                      Drug                                   

Name
Vidarabine sodium phosphate (USAN)
Formula
C10H12N5O7P. 2Na
Exact mass
391.027
Mol weight
391.1849
Structure
Simcomp
Class
Antiviral
 DG01440  Arabinofuranosyl type antiviral
 DG02840  Anti-herpesvirus agent
Remark
ATC code: J05AB03 S01AD06
Chemical structure group: DG00645
Product (DG00645): D06298<JP>
Efficacy
Antiviral, DNA polymerase ihibitor
Comment
Arabinofuranosyl derivative
Target
Herpesvirus DNA polymerase [KO:K18964]
Interaction
Structure map
map07041  Antineoplastics - antimetabolic agents
map07044  Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB03 Vidarabine
      D06300  Vidarabine sodium phosphate (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AD Antivirals
     S01AD06 Vidarabine
      D06300  Vidarabine sodium phosphate (USAN)
Antimicrobials [BR:br08307]
 Antivirals
  Genome replication inhibitor
   Herpesvirus DNA polymerase inhibitor
    D06300  Vidarabine sodium phosphate (USAN)
Antimicrobials abbreviations [BR:br08327]
 Antivirals
  Genome replication inhibitor
   Herpesvirus DNA polymerase inhibitor
    DG00645  Vidarabine
Other DBs
CAS: 71002-10-3
PubChem: 47207957
ChEMBL: CHEMBL3989651
DrugBank: DB00194
LigandBox: D06300
NIKKAJI: J19.191D
LinkDB
KCF data

ATOM        25
            1   N4y N    26.9305  -17.8935
            2   C8y C    27.9744  -18.6590
            3   C1y C    25.6084  -18.3110
            4   C8x C    27.3481  -16.5017
            5   C8y C    29.1574  -17.7544
            6   N5x N    28.1135  -20.0508
            7   O2x O    24.4950  -17.4760
            8   C1y C    25.1909  -19.5636
            9   N5x N    28.8094  -16.5017
            10  C8y C    30.4100  -18.3110
            11  C8x C    29.4358  -20.6075
            12  C1y C    23.3815  -18.2415
            13  C1y C    23.7991  -19.5636
            14  N5x N    30.6188  -19.7724
            15  N1a N    31.5234  -17.4760
            16  C1b C    22.0594  -17.8239
            17  O1a O    23.3815  -20.8858
            18  O2b O    21.0155  -18.7981
            19  P1b P    19.6238  -18.7981
            20  O1c O    18.2320  -18.7981 #-
            21  O1c O    19.6238  -20.1899 #-
            22  O1c O    19.6238  -17.3368
            23  O1a O    26.0185  -20.7126
            24  Z   Na   19.2500  -21.4900 #+
            25  Z   Na   15.8900  -18.7600 #+
BOND        25
            1     1   2 1
            2     3   1 1 #Up
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 2
            11    7  12 1
            12    8  13 1
            13   10  14 2
            14   10  15 1
            15   12  16 1 #Up
            16   13  17 1 #Down
            17   16  18 1
            18   18  19 1
            19   19  20 1
            20   19  21 1
            21   19  22 2
            22    5   9 1
            23   11  14 1
            24   12  13 1
            25    8  23 1 #Up

» Japanese version   » Back

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