| Entry |
|
|---|
| Name |
Alizapride (INN);
Plitican (TN) |
|---|
| Formula |
C16H21N5O2
|
|---|
| Exact mass |
315.1695
|
|---|
| Mol weight |
315.37
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
Gastrointestinal agent
DG01763 Propulsive
DG01762 Antiemetic
DG01783 Benzamide type antiemetic
|
|---|
| Remark |
|
|---|
| Efficacy |
Anti-emetic, Dopamine D2 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03F PROPULSIVES
A03FA Propulsives
A03FA05 Alizapride
D07102 Alizapride (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00058 Alizapride
D07102 Alizapride
Gastrointestinal agent
DG01763 Propulsive
DG00058 Alizapride
D07102 Alizapride
DG01762 Antiemetic
DG01783 Benzamide type antiemetic
DG00058 Alizapride
D07102 Alizapride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D07102 Alizapride (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00058 Alizapride
Gastrointestinal agent
DG01763 Propulsive
DG00058 Alizapride
DG01762 Antiemetic
DG01783 Benzamide type antiemetic
DG00058 Alizapride
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 23
1 C8y C 14.3500 -24.0100
2 C8y C 14.3500 -25.3400
3 C8x C 13.2300 -26.0400
4 C8y C 12.0400 -25.3400
5 C8y C 12.0400 -24.0100
6 C8x C 13.2300 -23.3800
7 N4x N 10.8500 -23.3100
8 N5x N 10.8500 -26.0400
9 N5x N 9.7300 -24.6400
10 O2a O 15.5400 -23.3800
11 C5a C 15.5400 -26.0400
12 N1b N 16.6600 -25.3400
13 C1b C 17.8500 -26.0400
14 O5a O 15.5400 -27.3700
15 C1a C 15.5400 -21.9800
16 C1y C 19.0681 -25.3499
17 N1y N 20.2021 -26.1207
18 C1x C 21.2820 -25.2771
19 C1x C 20.8133 -23.9893
20 C1x C 19.4438 -24.0371
21 C1b C 20.2483 -27.5099
22 C2b C 21.4691 -28.1617
23 C2a C 22.6825 -27.4066
BOND 25
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 4 8 1
9 7 9 1
10 9 8 2
11 1 10 1
12 2 11 1
13 11 12 1
14 12 13 1
15 11 14 2
16 10 15 1
17 13 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 16 20 1
23 17 21 1
24 21 22 1
25 22 23 2
|
|---|
