KEGG   DRUG: Alfentanil
Entry
D07122                      Drug                                   
Name
Alfentanil (INN);
Rapifen (TN)
Formula
C21H32N6O3
Exact mass
416.2536
Mol weight
416.52
Structure
Simcomp
Class
Neuropsychiatric agent
 DG02030  Anesthetics
  DG02027  General anesthetics
   DG02026  Opioid anesthetics
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Remark
Same as: C08005
ATC code: N01AH02
Chemical structure group: DG00792
Product (DG00792): D00835<US>
Efficacy
Analgesic (narcotic), Opioid receptor agonist
Comment
synthetic opioid
Phenylpiperidine derivative
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07039  Opioid analgesics
map07224  Opioid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01A ANESTHETICS, GENERAL
    N01AH Opioid anesthetics
     N01AH02 Alfentanil
      D07122  Alfentanil (INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG02030  Anesthetics
   DG02027  General anesthetics
    DG02026  Opioid anesthetics
     DG00792  Alfentanil
      D07122  Alfentanil
  DG01564  Opioid receptor agonist
   DG01563  mu-Opioid receptor agonist
    DG00792  Alfentanil
     D07122  Alfentanil
 Analgesic
  DG01984  Opioid analgesics
   DG00792  Alfentanil
    D07122  Alfentanil
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D07122  Alfentanil (INN)
Narcotics and psychotropics in Japan [br08308.html]
 Narcotics by Cabinet Order Article 1 (157 substances)
  D07122
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG02030  Anesthetics
   DG02027  General anesthetics
    DG02026  Opioid anesthetics
     DG00792  Alfentanil
  DG01564  Opioid receptor agonist
   DG01563  mu-Opioid receptor agonist
    DG00792  Alfentanil
 Analgesic
  DG01984  Opioid analgesics
   DG00792  Alfentanil
Other DBs
CAS: 71195-58-9
PubChem: 51091461
ChEBI: 2569
LigandBox: D07122
NIKKAJI: J330.279B
LinkDB
KCF data

ATOM        30
            1   C8x C    17.1500  -27.4400
            2   C8x C    17.1500  -28.8400
            3   C8x C    18.3400  -29.5400
            4   C8x C    19.6000  -28.8400
            5   C8y C    19.6000  -27.4400
            6   C8x C    18.3400  -26.7400
            7   N1c N    20.7900  -26.7400
            8   C1z C    22.0500  -27.4400
            9   C1x C    22.0500  -28.8400
            10  C1x C    23.2400  -29.5400
            11  N1y N    24.4300  -28.8400
            12  C1x C    24.4300  -27.4400
            13  C1x C    23.2400  -26.7400
            14  C1b C    25.6900  -29.5400
            15  C1b C    26.8800  -28.8400
            16  N4y N    28.0700  -29.5400
            17  N5x N    28.4200  -30.8700
            18  N5x N    29.8200  -30.8700
            19  N4y N    30.3100  -29.6100
            20  C8y C    29.1900  -28.7700
            21  C5a C    20.7900  -25.3400
            22  O5a O    19.6000  -24.6400
            23  C1b C    22.0500  -24.6400
            24  C1a C    23.2400  -25.3400
            25  C1b C    20.7900  -28.1400
            26  O2a O    20.7900  -29.5400
            27  C1a C    19.6000  -30.2400
            28  O5x O    29.1900  -27.3700
            29  C1b C    31.5000  -28.9100
            30  C1a C    32.6900  -29.6100
BOND        32
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14    8  13 1
            15   11  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 1
            22   16  20 1
            23    7  21 1
            24   21  22 2
            25   21  23 1
            26   23  24 1
            27    8  25 1
            28   25  26 1
            29   26  27 1
            30   20  28 2
            31   29  30 1
            32   29  19 1

» Japanese version   » Back

KEGG   DRUG: Alfentanil hydrochloride
Entry
D00835                      Drug                                   
Name
Alfentanil hydrochloride (USP);
Alfenta (TN)
Product
ALFENTANIL HYDROCHLORIDE (Akorn)
Formula
C21H32N6O3. HCl. H2O
Exact mass
470.2408
Mol weight
470.99
Structure
Simcomp
Class
Neuropsychiatric agent
 DG02030  Anesthetics
  DG02027  General anesthetics
   DG02026  Opioid anesthetics
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Remark
ATC code: N01AH02
Chemical structure group: DG00792
Product (DG00792): D00835<US>
Efficacy
Analgesic (narcotic), Opioid receptor agonist
Comment
synthetic opioid
Phenylpiperidine derivative
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07039  Opioid analgesics
map07224  Opioid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01A ANESTHETICS, GENERAL
    N01AH Opioid anesthetics
     N01AH02 Alfentanil
      D00835  Alfentanil hydrochloride (USP) <US>
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG02030  Anesthetics
   DG02027  General anesthetics
    DG02026  Opioid anesthetics
     DG00792  Alfentanil
      D00835  Alfentanil hydrochloride
  DG01564  Opioid receptor agonist
   DG01563  mu-Opioid receptor agonist
    DG00792  Alfentanil
     D00835  Alfentanil hydrochloride
 Analgesic
  DG01984  Opioid analgesics
   DG00792  Alfentanil
    D00835  Alfentanil hydrochloride
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D00835  Alfentanil hydrochloride (USP) <US>
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG02030  Anesthetics
   DG02027  General anesthetics
    DG02026  Opioid anesthetics
     DG00792  Alfentanil
  DG01564  Opioid receptor agonist
   DG01563  mu-Opioid receptor agonist
    DG00792  Alfentanil
 Analgesic
  DG01984  Opioid analgesics
   DG00792  Alfentanil
Other DBs
CAS: 69049-06-5
PubChem: 7847900
LigandBox: D00835
NIKKAJI: J334.451G
LinkDB
KCF data

ATOM        32
            1   X   Cl   28.3560  -24.6925
            2   O0  O    31.3257  -24.6656
            3   C8x C    15.9600  -27.4400
            4   C8x C    15.9600  -28.8400
            5   C8x C    17.1500  -29.5400
            6   C8x C    18.4100  -28.8400
            7   C8y C    18.4100  -27.4400
            8   C8x C    17.1500  -26.7400
            9   N1c N    19.6000  -26.7400
            10  C1z C    20.8600  -27.4400
            11  C1x C    20.8600  -28.8400
            12  C1x C    22.0500  -29.5400
            13  N1y N    23.2400  -28.8400
            14  C1x C    23.2400  -27.4400
            15  C1x C    22.0500  -26.7400
            16  C1b C    24.5000  -29.5400
            17  C1b C    25.6900  -28.8400
            18  N4y N    26.8800  -29.5400
            19  N5x N    27.2300  -30.8700
            20  N5x N    28.6300  -30.8700
            21  N4y N    29.1200  -29.6100
            22  C8y C    28.0000  -28.7700
            23  C5a C    19.6000  -25.3400
            24  O5a O    18.4100  -24.6400
            25  C1b C    20.8600  -24.6400
            26  C1a C    22.0500  -25.3400
            27  C1b C    19.6000  -28.1400
            28  O2a O    19.6000  -29.5400
            29  C1a C    18.4100  -30.2400
            30  O5x O    28.0000  -27.3700
            31  C1b C    30.3100  -28.9100
            32  C1a C    31.5000  -29.6100
BOND        32
            1     3   4 2
            2     4   5 1
            3     5   6 2
            4     6   7 1
            5     7   8 2
            6     3   8 1
            7     7   9 1
            8     9  10 1
            9    10  11 1
            10   11  12 1
            11   12  13 1
            12   13  14 1
            13   14  15 1
            14   10  15 1
            15   13  16 1
            16   16  17 1
            17   17  18 1
            18   18  19 1
            19   19  20 2
            20   20  21 1
            21   21  22 1
            22   18  22 1
            23    9  23 1
            24   23  24 2
            25   23  25 1
            26   25  26 1
            27   10  27 1
            28   27  28 1
            29   28  29 1
            30   22  30 2
            31   31  32 1
            32   31  21 1

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