KEGG   DRUG: AmfenacHelp
Entry
D07443                      Drug                                   

Name
Amfenac (INN)
Formula
C15H13NO3
Exact mass
255.0895
Mol weight
255.2686
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-inflammatory
 DG01906  Antiinflammatory drug, acetic acid derivatives
  DG01898  Antiinflammatory drug, phenylacetic acid derivatives
 DG01504  Nonsteroidal antiinflammatory drug (NSAID)
  DG01906  Antiinflammatory drug, acetic acid derivatives
   DG01898  Antiinflammatory drug, phenylacetic acid derivatives
Remark
Chemical structure group: DG01249
Product (DG01249): D01788<JP>
Efficacy
Analgesic, Anti-inflammatory, Antipyretic, COX inhibitor
Comment
Phenylacetic acid derivative
nonsteroidal antiinflammatory drugs (NSAIDs)
Target
PTGS1 (COX1) [HSA:5742] [KO:K00509]
PTGS2 (COX2) [HSA:5743] [KO:K11987]
  Pathway
hsa00590  Arachidonic acid metabolism
Interaction
Drug interaction
Structure map
map07219  Cyclooxygenase inhibitors
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Prostaglandin synthase
    PTGS1 (COX1)
     D07443  Amfenac (INN)
    PTGS2 (COX2)
     D07443  Amfenac (INN)
BRITE hierarchy
Other DBs
CAS: 51579-82-9
PubChem: 51091774
ChEBI: 75915
ChEMBL: CHEMBL25146
LigandBox: D07443
NIKKAJI: J11.225I
LinkDB All DBs
KCF data Show

ATOM        19
            1   C8x C    18.6900  -17.9200
            2   C8x C    18.6900  -19.3200
            3   C8x C    19.9500  -20.0200
            4   C8x C    21.1400  -19.3200
            5   C8y C    21.1400  -17.9200
            6   C8x C    19.9500  -17.2200
            7   C5a C    22.3300  -17.2200
            8   C8y C    23.5200  -17.9200
            9   O5a O    22.3300  -15.8200
            10  C8x C    23.5200  -19.3200
            11  C8x C    24.7800  -20.0200
            12  C8x C    25.9700  -19.3200
            13  C8y C    25.9700  -17.9200
            14  C8y C    24.7800  -17.2200
            15  N1a N    24.7800  -15.8200
            16  C1b C    27.1600  -17.2200
            17  C6a C    28.4200  -17.9200
            18  O6a O    29.6100  -17.2200
            19  O6a O    28.4200  -19.3200
BOND        20
            1     2   3 1
            2     3   4 2
            3     4   5 1
            4     5   6 2
            5     6   1 1
            6     8  10 2
            7    10  11 1
            8    11  12 2
            9    12  13 1
            10   13  14 2
            11   14   8 1
            12   14  15 1
            13    5   7 1
            14   13  16 1
            15   16  17 1
            16    7   8 1
            17   17  18 1
            18    1   2 2
            19   17  19 2
            20    7   9 2

» Japanese version   » Back

DBGET integrated database retrieval system