KEGG   DRUG: Cyclopentolate
Entry
D07759                      Drug                                   
Name
Cyclopentolate (INN);
Bell Pentolate (TN)
Formula
C17H25NO3
Exact mass
291.1834
Mol weight
291.3853
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Remark
Same as: C06932
ATC code: S01FA04
Chemical structure group: DG01141
Product (DG01141): D01002<JP/US>
Efficacy
Mydriatic, Muscarinic acetylcholine receptor antagonist
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Structure map
map07220  Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01F MYDRIATICS AND CYCLOPLEGICS
    S01FA Anticholinergics
     S01FA04 Cyclopentolate
      D07759  Cyclopentolate (INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01491  Muscarinic cholinergic receptor antagonist
   DG01141  Cyclopentolate
    D07759  Cyclopentolate
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D07759  Cyclopentolate (INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01491  Muscarinic cholinergic receptor antagonist
   DG01141  Cyclopentolate
Other DBs
CAS: 512-15-2
PubChem: 51092051
ChEBI: 4024
LigandBox: D07759
NIKKAJI: J6.274J
LinkDB
KCF data

ATOM        21
            1   C8x C    29.6100  -19.0400
            2   C8x C    29.6100  -20.4400
            3   C8x C    28.3500  -21.1400
            4   C8x C    27.1600  -20.4400
            5   C8y C    27.1600  -19.0400
            6   C8x C    28.3500  -18.3400
            7   C1c C    25.9000  -18.3400
            8   C7a C    24.7100  -19.0400
            9   C1z C    25.9000  -16.9400
            10  C1x C    24.7800  -16.1000
            11  C1x C    25.2000  -14.7700
            12  C1x C    26.6000  -14.7700
            13  C1x C    27.0200  -16.1000
            14  O7a O    23.5200  -18.3400
            15  C1b C    22.3300  -19.0400
            16  O6a O    24.7100  -20.4400
            17  C1b C    21.1400  -18.3400
            18  N1c N    19.9500  -19.0400
            19  C1a C    18.6900  -18.3400
            20  O1a O    27.3000  -16.9400
            21  C1a C    19.8800  -20.4400
BOND        22
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     7   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14    9  13 1
            15    8  14 1
            16   14  15 1
            17    8  16 2
            18   15  17 1
            19   17  18 1
            20   18  19 1
            21    9  20 1
            22   18  21 1

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KEGG   DRUG: Cyclopentolate hydrochloride
Entry
D01002                      Drug                                   
Name
Cyclopentolate hydrochloride (JP18/USP);
Cyclogyl (TN)
Product
  Generic
Formula
C17H25NO3. HCl
Exact mass
327.1601
Mol weight
327.8462
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Remark
Therapeutic category: 1311
ATC code: S01FA04
Chemical structure group: DG01141
Product (DG01141): D01002<JP/US>
Product (mixture): D11698<US>
Efficacy
Mydriatic, Muscarinic acetylcholine receptor antagonist
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Structure map
map07220  Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01F MYDRIATICS AND CYCLOPLEGICS
    S01FA Anticholinergics
     S01FA04 Cyclopentolate
      D01002  Cyclopentolate hydrochloride (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
 Ophthalmic Agents
  Ophthalmic Agents, Other
   Cycloplegic Mydriatics
    Cyclopentolate
     D01002  Cyclopentolate hydrochloride (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1311  Mydriatic agents
     D01002  Cyclopentolate hydrochloride (JP18/USP)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01491  Muscarinic cholinergic receptor antagonist
   DG01141  Cyclopentolate
    D01002  Cyclopentolate hydrochloride
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D01002  Cyclopentolate hydrochloride (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01002  Cyclopentolate hydrochloride
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01491  Muscarinic cholinergic receptor antagonist
   DG01141  Cyclopentolate
Other DBs
CAS: 5870-29-1
PubChem: 7848065
ChEBI: 4025
LigandBox: D01002
NIKKAJI: J220.042B
LinkDB
KCF data

ATOM        22
            1   X   Cl   29.4700  -22.1900
            2   C8x C    25.9700  -22.7500
            3   C8x C    25.9700  -24.1500
            4   C8x C    24.7100  -24.8500
            5   C8x C    23.5200  -24.1500
            6   C8y C    23.5200  -22.7500
            7   C8x C    24.7100  -22.0500
            8   C1c C    22.2600  -22.0500
            9   C7a C    21.0700  -22.7500
            10  C1z C    22.2600  -20.6500
            11  C1x C    21.1400  -19.8100
            12  C1x C    21.5600  -18.4800
            13  C1x C    22.9600  -18.4800
            14  C1x C    23.3800  -19.8100
            15  O7a O    19.8800  -22.0500
            16  C1b C    18.6900  -22.7500
            17  O6a O    21.0700  -24.1500
            18  C1b C    17.5000  -22.0500
            19  N1c N    16.2400  -22.7500
            20  C1a C    15.0500  -22.0500
            21  O1a O    23.6600  -20.6500
            22  C1a C    16.2400  -24.1500
BOND        22
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     6   8 1
            8     8   9 1
            9     8  10 1
            10   10  11 1
            11   11  12 1
            12   12  13 1
            13   13  14 1
            14   10  14 1
            15    9  15 1
            16   15  16 1
            17    9  17 2
            18   16  18 1
            19   18  19 1
            20   19  20 1
            21   10  21 1
            22   19  22 1

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